Personal profile
Chinese Name
Biography
Professor Li Min (李敏教授) is an acclaimed scholar in the treatment of neurodegenerative diseases using Chinese medicine. She is a research scientist in the field of autophagy, Chinese medicinal pharmacology in treating and prevention of Parkinson’s disease (PD), Alzheimer's disease (AD) and Amyotrophic lateral sclerosis (ALS). Professor Li was named the First National Outstanding Female Chinese Medicine Practitioner (全國首屆傑出女中醫師) in 2007 and has consistently been ranked among the world’s top 2% scientists by Stanford University in recent years.
Joining Hong Kong Baptist University (HKBU) in 2001, Professor Li currently holds several positions in the School of Chinese Medicine (SCM): Chair Professor of Chinese Medicine, Ma Pak Leung Endowed Professor in Innovative Neuromedicine, Programme Director of Bachelor of Chinese Medicine & Bachelor of Science (Hons) in Biomedical Science, and also the Director of Mr. & Mrs. Ko Chi Ming Centre for Parkinson's Disease Research (CPDR) and Golden Meditech Centre for NeuroRegeneration Sciences (GCNS). Professor Li officially succeeds Professor Lyu Aiping as the Dean of School of Chinese Medicine effective 1 April 2025.
Professor Li obtained her bachelor’s degree in Chinese medicine from Henan University of Chinese Medicine in Zhengzhou, China, in 1985. She also earned a master’s degree in Chinese medicine from Guangzhou University of Chinese Medicine in Guangzhou, China, in 1988, and completed her PhD in Cardiology at the School of Medicine, Tokai University, Kanagawa, Japan, in 2001. Prof. Li joined the School of Chinese Medicine in Hong Kong Baptist University (HKBU) in 2001 as an Assistant Professor. She was promoted to Full Professor in 2014, appointed as the Endowed Professor in Innovative Neuromedicine in 2024, and became a Chair Professor in 2025.
Research Interests
Prof. Li's long-term research interests include:
- The relationship between autophagy regulation and neurodegenerative diseases such as Parkinson's Disease (PD), Alzheimer's Disease (AD), and Amyotrophic Lateral Sclerosis (ALS).
- The use of Traditional Chinese Medicine (TCM) for the prevention and treatment of neurodegenerative diseases.
- The development of molecular targets for new drug discovery from TCM for neurodegenerative diseases.
Prof. Li's current research directions focus on:
- Autophagy regulation in neurodegenerative diseases, including Alzheimer's Disease (AD), Parkinson's Disease (PD), and Amyotrophic Lateral Sclerosis (ALS).
- Understanding the neuroprotective effects and underlying mechanisms of TCM on neurodegenerative diseases, including AD, PD, and ALS.
- Investigating the efficacy and safety of TCM in the treatment of neurodegenerative diseases, such as AD and PD, through randomized controlled clinical trials, as well as exploring the interaction between TCM and Western medicine.
Education/Academic qualification
-, PhD, PhD Program in Medicine, School of Medicine, Tokai University, Japan
1 Apr 1998 → 31 Mar 2001
Award Date: 31 Mar 2001
Master, Master Program of Chinese Medicine, Guangzhou University of Chinese Medicine
1 Sept 1985 → 30 Jun 1988
Award Date: 30 Jun 1988
Bachelor, Bachelor Program of Chinese Medicine , Henan University of Chinese Medicine
1 Sept 1980 → 31 Jul 1985
Award Date: 31 Jul 1985
Keywords
- RZ Other systems of medicine
- Internal medicine of Chinese medicine
- Neurodegenerative diseases
- Autophagy
- Neuropharmacology
- Parkinson's disease
- Alzheimer's disease
- Higher education in Chinese medicine
- Clinical study of Chinese medicine
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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A novel mechanism of autophagy-lysosome pathway impairment in Alzheimer disease-associated neuropathogenesis: Role of AKAP11-mediated autophagy and PKA signaling
DENG, Z. (PI), Yue, Z. (CoI) & LI, M. (CoI)
1/01/26 → 31/12/28
Project: Research project
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基于TFEB介导的自噬通路探究AKAP11基因缺失导致精神分裂症的发病机制
DENG, Z. (PI), LI, M. (Collaborator), Kan , Y. (Collaborator), LIU, J. (Collaborator), GUAN, X. (Collaborator), LU, J. (Collaborator) & XU, X. (Collaborator)
1/01/26 → 31/12/28
Project: Research project
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Investigating the mechanism of (-)Schisandrin B on the treatment of Parkinson's disease via regulating ATG16L1/NLRP3 signalling pathway
LI, M. (PI), Song, J.-X. (CoI), IYASWAMY, A. (CoI) & DENG, Z. (CoI)
9/10/24 → 8/10/27
Project: Research project
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Development of an explainable machine learning model for predicting poststroke anxiety: A multicenter study using Shapley Additive Explanations and nomogram visualization
Lyu, M., Xie, Y., Li, M., Hölscher, C. & Shen, X., 8 Jan 2026, In: Digital Health. 12, 21 p.Research output: Contribution to journal › Journal article › peer-review
Open Access -
30th Anniversary of Phytomedicine: Looking Back and Forth
Efferth, T., Zacchino, S., Georgiev, M., He, R.-R., Shen, X., Albrecht, U., Belwal , T., Bhutia, S. K., Chatterjee, M., Chen, J., Chen, Z.-Y., Cho, W., Devi, S. I., Eid, A. H., Orhan, I. E., Gao, Y., Hosseinzadeh, H., Hua, Q., Khan, H. & Kuete, V. & 22 others, , Dec 2025, In: Phytomedicine. 149, 4 p., 157525.Research output: Contribution to journal › Journal article
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Discovery of S1P/SPHK1 dysregulation in Parkinson's disease and its role in pathological α-synuclein-induced neurodegeneration
Fang, J. (Co-first author), Wang, X. (Co-first author), Su, X., Li, D., Wang, F., Wang, P., Yuan, C., Ji, F., Zhang, D., Cai, X., Liu, W., Li, M., Hu, S. & Cai, Z., 24 Nov 2025, In: Innovation Life. 3, 4, 12 p., 100164.Research output: Contribution to journal › Journal article › peer-review
Open Access -
Electroacupuncture ameliorates tau-driven cognitive decline by modulating NF-κB/NLRP3 inflammasome signaling in P301S mice
Zheng, R., Liu, X., Liao, Z., Wan, R., Qiu, G., Li, M., Tang, C., Zhou, R. & Song, J., Apr 2026, In: Experimental Neurology. 398, 11 p., 115637.Research output: Contribution to journal › Journal article › peer-review
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From Adipose to Action: Reprogramming Stem Cells for Functional Neural Progenitors for Neural Regenerative Therapy
Peng, J., Zhang, Z., Li, M., Yung, K. K. L. & Cheung, K. H., 9 Jul 2025, In: International Journal of Molecular Sciences. 26, 14, 21 p., 6599.Research output: Contribution to journal › Journal article › peer-review
Open Access1 Citation (Scopus)
Prizes
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Best Poster Prize (“NRBF2 is involved in the degradation process of APP-CTFs in Alzheimer disease models”)
LI, M. (Recipient), 5 Sept 2017
Prize
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President’s Award for Outstanding Performance in Research Supervision
LI, M. (Recipient), 2 May 2024
Prize: Award
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Activities
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TFE3 deficiency aggravates tauopathy and impairs memory in mice involving CAPON accumulation
LI, M. (Speaker)
26 Mar 2023 → 29 Mar 2023Activity: Conference/talk/lecture/symposium/speech/workshop, etc › Event organized by non-HKBU units
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Studying the mechanism of (-)Schisandrin B on the treatment of Parkinson's disease via ATG16L1/NLRP3 signaling pathway
LI, M. (Participant)
26 Mar 2023 → 29 Mar 2023Activity: Conference/talk/lecture/symposium/speech/workshop, etc › Event organized by non-HKBU units
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Corynoxine has neuroprotective effects in experimental Alzheimer’s disease models via TFEB/TFE3-mediated autophagy induction
LI, M. (Speaker)
26 Mar 2023 → 29 Mar 2023Activity: Conference/talk/lecture/symposium/speech/workshop, etc › Event organized by non-HKBU units
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以中醫經典為導向的中醫臨床專科研修教學
LI, M. (Speaker)
28 Aug 2022Activity: Conference/talk/lecture/symposium/speech/workshop, etc › Event organized by non-HKBU units
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Targeting autophagy for novel Chinese medicine development for Parkinson’s disease treatment
LI, M. (Plenary/keynote speaker)
27 Aug 2022Activity: Conference/talk/lecture/symposium/speech/workshop, etc › Event organized by non-HKBU units
Press/Media
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HKBU scientists develop versatile compound for treating Alzheimer’s disease
IYASWAMY, A., LI, M. & Wong, M. S.
24/08/22
1 Media contribution
Press/Media
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HKBU develops versatile compound F-SLOH for Alzheimer’s disease treatment
24/08/22
1 item of Media coverage
Press/Media
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HKBU researchers invent Chinese medicine formula for Alzheimer’s disease
IYASWAMY, A. & LI, M.
3/02/21
1 Media contribution
Press/Media