Projects per year
Personal profile
Chinese Name
Biography
Professor Li Min (李敏教授) is an acclaimed scholar in the treatment of neurodegenerative diseases using Chinese medicine. She is a research scientist in the field of autophagy, Chinese medicinal pharmacology in treating and prevention of Parkinson’s disease (PD), Alzheimer's disease (AD) and Amyotrophic lateral sclerosis (ALS). Professor Li was named the First National Outstanding Female Chinese Medicine Practitioner (全國首屆傑出女中醫師) in 2007 and has consistently been ranked among the world’s top 2% scientists by Stanford University in recent years.
Joining Hong Kong Baptist University (HKBU) in 2001, Professor Li currently holds several positions in the School of Chinese Medicine (SCM): Chair Professor of Chinese Medicine, Ma Pak Leung Endowed Professor in Innovative Neuromedicine, Programme Director of Bachelor of Chinese Medicine & Bachelor of Science (Hons) in Biomedical Science, and also the Director of Mr. & Mrs. Ko Chi Ming Centre for Parkinson's Disease Research (CPDR) and Golden Meditech Centre for NeuroRegeneration Sciences (GCNS). Professor Li officially succeeds Professor Lyu Aiping as the Dean of School of Chinese Medicine effective 1 April 2025.
Professor Li obtained her bachelor’s degree in Chinese medicine from Henan University of Chinese Medicine in Zhengzhou, China, in 1985. She also earned a master’s degree in Chinese medicine from Guangzhou University of Chinese Medicine in Guangzhou, China, in 1988, and completed her PhD in Cardiology at the School of Medicine, Tokai University, Kanagawa, Japan, in 2001. Prof. Li joined the School of Chinese Medicine in Hong Kong Baptist University (HKBU) in 2001 as an Assistant Professor. She was promoted to Full Professor in 2014, appointed as the Endowed Professor in Innovative Neuromedicine in 2024, and became a Chair Professor in 2025.
Research Interests
Prof. Li's long-term research interests include:
- The relationship between autophagy regulation and neurodegenerative diseases such as Parkinson's Disease (PD), Alzheimer's Disease (AD), and Amyotrophic Lateral Sclerosis (ALS).
- The use of Traditional Chinese Medicine (TCM) for the prevention and treatment of neurodegenerative diseases.
- The development of molecular targets for new drug discovery from TCM for neurodegenerative diseases.
Prof. Li's current research directions focus on:
- Autophagy regulation in neurodegenerative diseases, including Alzheimer's Disease (AD), Parkinson's Disease (PD), and Amyotrophic Lateral Sclerosis (ALS).
- Understanding the neuroprotective effects and underlying mechanisms of TCM on neurodegenerative diseases, including AD, PD, and ALS.
- Investigating the efficacy and safety of TCM in the treatment of neurodegenerative diseases, such as AD and PD, through randomized controlled clinical trials, as well as exploring the interaction between TCM and Western medicine.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
-, PhD, PhD Program in Medicine, School of Medicine, Tokai University, Japan
1 Apr 1998 → 31 Mar 2001
Award Date: 31 Mar 2001
Master, Master Program of Chinese Medicine, Guangzhou University of Chinese Medicine
1 Sept 1985 → 30 Jun 1988
Award Date: 30 Jun 1988
Bachelor, Bachelor Program of Chinese Medicine , Henan University of Chinese Medicine
1 Sept 1980 → 31 Jul 1985
Award Date: 31 Jul 1985
Keywords
- RZ Other systems of medicine
- Internal medicine of Chinese medicine
- Neurodegenerative diseases
- Autophagy
- Neuropharmacology
- Parkinson's disease
- Alzheimer's disease
- Higher education in Chinese medicine
- Clinical study of Chinese medicine
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Collaborations and top research areas from the last five years
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Investigating the mechanism of (-)Schisandrin B on the treatment of Parkinson's disease via regulating ATG16L1/NLRP3 signalling pathway
LI, M. (PI), Song, J.-X. (CoI), IYASWAMY, A. (CoI) & DENG, Z. (CoI)
9/10/24 → 8/10/27
Project: Research project
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代謝類疾病證候特點及中醫療效前瞻觀察性先導研究 [Clinical characterization of metabolic diseases and prospective pilot cohort]
CHAN, K. W. (PI), LI, M. (CoI), HUANG, X.-Z. (CoI) & LYU, H. (CoI)
1/07/24 → 30/06/26
Project: Research project
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Incorporating emerging technologies to healthcare education: Using Public Health and Family Medicine as a pilot
CHAN, K. W. (PI), LI, M. (CoI), CHEN, H. (CoI), XU, J. (CoI) & QIN, S. (CoI)
1/12/23 → 30/06/26
Project: Teaching project
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Impairment of autophagy-lysosomal pathway in Parkinson's disease: Novel roles of HMGB1-TFEB interplay and therapeutic implication of Chinese medicine compounds
LI, M. (PI) & Song, J. (CoI)
1/01/23 → 31/12/25
Project: Research project
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From Adipose to Action: Reprogramming Stem Cells for Functional Neural Progenitors for Neural Regenerative Therapy
Peng, J., Zhang, Z., Li, M., Yung, K. K. L. & Cheung, K. H., 9 Jul 2025, In: International Journal of Molecular Sciences. 26, 14, 21 p., 6599.Research output: Contribution to journal › Journal article › peer-review
Open Access1 Citation (Scopus) -
MT1-MMP inhibition rejuvenates ageing brain and rescues cognitive deficits in obesity
Asthana, P. (Co-first author), Li, L. (Co-first author), Lu, L. (Co-first author), Wu, J. (Co-first author), Zhang, S., Li, N., Wong, S. K. K., Gurung, S., Zhang, Y., Lin, Y., Peng, Y., Xu, Z., Chan, K. M., Zhai, L., Lyu, A., Bian, Z.-X., Ge, X., Iyaswamy, A., Li, M. & Su, Y. & 3 others, , 23 Sept 2025, In: Cell Discovery. 11, 1, 17 p., 76.Research output: Contribution to journal › Journal article › peer-review
Open Access -
Nanomaterial-based synergistic strategies for combating dental caries: progress and perspectives
Xu, K., Huang, R., Li, X., Jin, L., Ko, C.-N., Li, M., Wong, H. M. & Leung, K.C.-F., 28 Jan 2025, In: Nanoscale. 17, 4, p. 1874-1888 15 p.Research output: Contribution to journal › Journal article › peer-review
Open Access2 Citations (Scopus) -
Rational Design of Palladium and Platinum Chemosensors for Bio-Applications
Tritton, D. N., Kwan, C.-S., Tang, F.-K., Cai, Z., Li, M. & Leung, K.C.-F., Feb 2025, In: Advanced Sensor Research. 4, 2, 38 p., 2400150.Research output: Contribution to journal › Journal article › peer-review
Open Access -
Smart Hydrogels in Wearable Electronics for Wound Treatments
Li, B., Li, M. & Wang, Y., 29 Sept 2025, (E-pub ahead of print) In: Small. 31 p., e07368.Research output: Contribution to journal › Journal article › peer-review
Open Access
Prizes
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Best Poster Prize (“NRBF2 is involved in the degradation process of APP-CTFs in Alzheimer disease models”)
LI, M. (Recipient), 5 Sept 2017
Prize
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President’s Award for Outstanding Performance in Research Supervision
LI, M. (Recipient), 2 May 2024
Prize: Award
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Activities
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TFE3 deficiency aggravates tauopathy and impairs memory in mice involving CAPON accumulation
LI, M. (Speaker)
26 Mar 2023 → 29 Mar 2023Activity: Conference/talk/lecture/symposium/speech/workshop, etc › Event organized by non-HKBU units
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Studying the mechanism of (-)Schisandrin B on the treatment of Parkinson's disease via ATG16L1/NLRP3 signaling pathway
LI, M. (Participant)
26 Mar 2023 → 29 Mar 2023Activity: Conference/talk/lecture/symposium/speech/workshop, etc › Event organized by non-HKBU units
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Corynoxine has neuroprotective effects in experimental Alzheimer’s disease models via TFEB/TFE3-mediated autophagy induction
LI, M. (Speaker)
26 Mar 2023 → 29 Mar 2023Activity: Conference/talk/lecture/symposium/speech/workshop, etc › Event organized by non-HKBU units
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以中醫經典為導向的中醫臨床專科研修教學
LI, M. (Speaker)
28 Aug 2022Activity: Conference/talk/lecture/symposium/speech/workshop, etc › Event organized by non-HKBU units
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Targeting autophagy for novel Chinese medicine development for Parkinson’s disease treatment
LI, M. (Plenary/keynote speaker)
27 Aug 2022Activity: Conference/talk/lecture/symposium/speech/workshop, etc › Event organized by non-HKBU units
Press/Media
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HKBU scientists develop versatile compound for treating Alzheimer’s disease
IYASWAMY, A., LI, M. & Wong, M. S.
24/08/22
1 Media contribution
Press/Media
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HKBU develops versatile compound F-SLOH for Alzheimer’s disease treatment
24/08/22
1 item of Media coverage
Press/Media
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HKBU researchers invent Chinese medicine formula for Alzheimer’s disease
IYASWAMY, A. & LI, M.
3/02/21
1 Media contribution
Press/Media
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