Projects per year
Personal profile
Chinese Name
Biography
Dr. Cheung’s research interests are immunology and metabolic diseases. His research work has been published in internationally renowned journals including Immunity, Nature Communications, Cell Metabolism, Clinical Cancer Research, PNAS and British Journal of Pharmacology.
Research Interests
As an immunologist, I possess a deep passion for my field and extensive knowledge in cardiovascular, cancer, and immunology. Currently, my primary focus lies in T Cell therapy.
In our research program, we utilize a range of approaches including metabolomics, immunology, bioinformatics, and molecular biology to identify the causes of cancer in various tumor types and explore key metabolic pathways involved in carcinogenesis. Our laboratory operates a cutting-edge metabolomics program that quantitatively profiles endogenous small-molecule metabolites and trace elements from biological specimens such as blood, urine, saliva, cell lysates, and tissues from experimental animals and human subjects. This program involves unbiased metabolic profiling and data mining, metabolite annotation, and biological interpretation, as well as targeted analysis of metabolic flux and pathways using isotope-labeled metabolites and high sensitivity, high throughput LC-MS-MS and GC-MS platforms.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, Immunology, Queens Mary University (London)
Master, Medical Science, The University of Hong Kong
Bachelor, Biotechnology, with industrial placement at GSK (London), University College London
Keywords
- QR180 Immunology
- T cell
- Metabolism
- Vascular
- inflammation
- lipid
- R Medicine (General)
- metabolic syndromes
- cancer
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Collaborations and top research areas from the last five years
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Research on the construction of a comprehensive prevention and treatment system for the transformation of chronic atrophic gastritis to "inflammation-cancer" and the development of effective proprietary Chinese medicines
Li, P. (PI), CHEUNG, K. C. P. (CoI), Chen, X. (CoI) & Chen, Q. (CoI)
1/10/24 → 30/09/27
Project: Research project
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Investigating and examining the role of Hyocholic acid signalling in athero-immunometabolism
CHEUNG, K. C. P. (PI), JIA, W. (CoI) & Xiao, Q. (External CoI)
1/01/24 → 31/12/26
Project: Research project
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粵港澳新藥篩選聯合實驗室
Bi, H. (PI), CHEUNG, K. C. P. (CoI) & JIA, W. (CoI)
1/06/23 → 31/05/26
Project: Research project
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Dysregulated Host - Gut Microbiota Co-Metabolism in Metabolic Associated Fatty Liver Disease
JIA, W. (PI) & CHEUNG, K. C. P. (CoI)
1/01/24 → 31/12/24
Project: Research project
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Exploring fructose metabolism as a potential therapeutic approach for pancreatic cancer
Wang, C., Wang, L., Zhao, Q., Ma, J., Li, Y., Kuang, J., Yang, X., Lu, A., Cheung, K. C. P., Melino, G. & Jia, W., Dec 2024, In: Cell Death and Differentiation. 31, 12, p. 1625-1635 11 p.Research output: Contribution to journal › Journal article › peer-review
2 Citations (Scopus) -
Hyodeoxycholic acid alleviates non-alcoholic fatty liver disease through modulating the gut-liver axis
Kuang, J., Wang, J., Li, Y., Li, M., Zhao, M., Ge, K., Zheng, D., Cheung, K. C. P., Liao, B., Wang, S., Chen, T., Zhang, Y., Wang, C., Ji, G., Chen, P., Zhou, H., Xie, C., Zhao, A., Jia, W. & Zheng, X. & 1 others, , 3 Oct 2023, In: Cell Metabolism. 35, 10, p. 1752-1766.e8 24 p.Research output: Contribution to journal › Journal article › peer-review
Open Access126 Citations (Scopus) -
Regulatory T Cell Migration Is Dependent on Glucokinase-Mediated Glycolysis
Kishore, M., Cheung, K. C. P., Fu, H., Bonacina, F., Wang, G., Coe, D., Ward, E. J., Colamatteo, A., Jangani, M., Baragetti, A., Matarese, G., Smith, D. M., Haas, R., Mauro, C., Wraith, D. C., Okkenhaug, K., Catapano, A. L., De Rosa, V., Norata, G. D. & Marelli-Berg, F. M., 21 Nov 2017, In: Immunity. 47, 5, p. 875-889.e10 25 p.Research output: Contribution to journal › Journal article › peer-review
Open Access182 Citations (Scopus) -
Preservation of microvascular barrier function requires CD31 receptor-induced metabolic reprogramming
Cheung, K. C. P., Fanti, S., Mauro, C., Wang, G., Nair, A. S., Fu, H., Angeletti, S., Spoto, S., Fogolari, M., Romano, F., Aksentijevic, D., Liu, W., Li, B., Cheng, L., Jiang, L., Vuononvirta, J., Poobalasingam, T. R., Smith, D. M., Ciccozzi, M. & Solito, E. & 1 others, , 17 Jul 2020, In: Nature Communications. 11, 1, 18 p., 3595.Research output: Contribution to journal › Journal article › peer-review
Open Access37 Citations (Scopus) -
CD31 signals confer immune privilege to the vascular endothelium
Cheung, K. C. P., Ma, L., Wang, G., Coe, D., Ferro, R., Falasca, M., Buckley, C. D., Mauro, C. & Marelli-Berg, F. M., 27 Oct 2015, In: Proceedings of the National Academy of Sciences of the United States of America. 112, 43, p. E5815-5824 10 p.Research output: Contribution to journal › Journal article › peer-review
Open Access54 Citations (Scopus)
Activities
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Frontiers in Cell and Developmental Biology (Journal)
CHEUNG, K. C. P. (Associate editor)
1 Mar 2023Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)
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Frontiers in Immunology (Journal)
CHEUNG, K. C. P. (Reviewer)
1 Apr 2023Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)
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Biomedicine (Journal)
CHEUNG, K. C. P. (Reviewer)
1 Mar 2023Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)
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The London Inflammation Network (LIN) (External organisation)
CHEUNG, K. C. P. (General member)
1 Sept 2017Activity: Membership › Membership of societies
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British Society for Immunology (External organisation)
CHEUNG, K. C. P. (General member)
1 Jan 2012Activity: Membership › Membership of societies
Press/Media
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HKBU secures Theme-based Research Scheme funding to study metabolic associated fatty liver disease with metabolomics
13/07/23
1 Media contribution
Press/Media