Projects per year
Personal profile
Biography
Dr. Iyaswamy Ashok, is currently a Research Assistant Professor at School of Chinese Medicine, HKBU. After graduated from India,he spent seven years of Research Fellow/Postdoc Fellow training at HKBU. His research interests focus on Neurodegenerative disease,Chinese medicine and Autophagy.
2020 – Present Research Assistant Professor, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR
2017 – 2020 Post-Doctoral Research Fellow, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR
2014 – 2017 Senior Research Assistant, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR
2013 - 2014 Senior Research Fellow, IBMS, University of Madras, India.
2009 - 2013 University Research Fellow, IBMS, University of Madras, India.
Research Interests
1. Understanding the molecular mechanisms and pathophysiology of Alzheimer’s disease and other neurodegenerative diseases.
2. Developing potential methods for brain drug delivery system and biomaterials for diagnosis of neurodegenerative diseases.
3. Identifying possible benefits of Chinese herbal medicine for prevention and treatment of neurodegenerative diseases.
Research Interests
Research Interests
1. Understanding the molecular mechanisms and pathophysiology of Alzheimer’s disease and other neurodegenerative diseases.
2. Developing potential methods for brain drug delivery system and biomaterials for diagnosis of neurodegenerative diseases.
3. Identifying possible benefits of Chinese herbal medicine for prevention and treatment of neurodegenerative diseases.
Chinese Name
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, Physiology- Biotechnology, Institute of Basic Medical Sciences, University of Madras
27 Jul 2009 → 27 Feb 2015
Award Date: 27 Feb 2015
Master, MSc Biotechnology, Loyola college, University of Madras
1 Apr 2005 → 30 May 2007
Award Date: 1 Jun 2007
Bachelor, BSc Biotechnology, ANJA college, Madurai Kamaraj University
1 Apr 2002 → 30 Mar 2005
Award Date: 30 Apr 2005
Keywords
- RM Therapeutics. Pharmacology
- RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
- QP Physiology
- RS Pharmacy and materia medica
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Collaborations and top research areas from the last five years
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Investigating the mechanism of (-)Schisandrin B on the treatment of Parkinson's disease via regulating ATG16L1/NLRP3 signalling pathway
LI, M., Song, J., IYASWAMY, A. & DENG, Z.
9/10/24 → 8/10/27
Project: Research project
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Neuroprotective effects Chinese medicine Corynoxine in experimental Alzheimer's disease via autophagy induction
1/09/20 → 31/08/23
Project: Research project
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Aspartame Causes Developmental Defects and Teratogenicity in Zebra Fish Embryo: Role of Impaired SIRT1/FOXO3a Axis in Neuron Cells
Pandaram, A., Paul, J., Wankhar, W., Thakur, A., Verma, S., Vasudevan, K., Wankhar, D., Kammala, A. K., Sharma, P., Jaganathan, R., Iyaswamy, A. & Rajan, R., Apr 2024, In: Biomedicines. 12, 4, 19 p., 855.Research output: Contribution to journal › Journal article › peer-review
Open Access3 Citations (Scopus) -
Corynoxine promotes TFEB/TFE3-mediated autophagy and alleviates Aβ pathology in Alzheimer’s disease models
Guan, X., Deng, Z., Liu, J., Su, C., Tong, B. C. K., Zhu, Z., Sreenivasmurthy, S. G., Kan, Y., Lu, K., Chu, C. P. K., Pi, R., Cheung, K., Iyaswamy, A., Song, J. & Li, M., May 2024, In: Acta Pharmacologica Sinica. 45, 5, p. 900–913 14 p.Research output: Contribution to journal › Journal article › peer-review
6 Citations (Scopus) -
EXOSOMAL COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASES
LI, M., IYASWAMY, A., Chen, H. J. & Thakur, A., 18 Jul 2024, IPC No. A61-LM-Fe65-PT01, 9 Jan 2024, Priority date 13 Jan 2023, Priority No. PCT/CN2024/071455Research output: Patent
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Insight into Tetrabromobisphenol A-Associated Liver Transcriptional Landscape via Single Cell RNA Sequencing
Bai, Y., Zhu, Z., Ou, J., Zhang, W., Iyaswamy, A., Jiang, Y., Wang, J., Zhang, W. & Yang, C., Feb 2024, In: Advanced Biology. 8, 2, 2300477.Research output: Contribution to journal › Journal article › peer-review
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Integrated RNA sequencing and biochemical studies reveal endoplasmic reticulum stress and autophagy dysregulation contribute to Tri (2-Ethylhexyl) phosphate (TEHP)-induced cell injury in Sertoli cells
Chen, P., Song, Y., Tang, L., Qiu, Z., Chen, J., Xia, S., Iyaswamy, A., Cai, J., Sun, Y., Yang, C. & Wang, J., 1 Nov 2024, In: Environmental Pollution. 360, 13 p., 124536.Research output: Contribution to journal › Journal article › peer-review
Prizes
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Activities
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Pharmaceutics (Journal)
Ashok IYASWAMY (Guest editor)
11 Jun 2025Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)
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European Journal of Medicinal Chemistry Reports (Journal)
Ashok IYASWAMY (Reviewer)
Mar 2024Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)
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iScience (Journal)
Ashok IYASWAMY (Reviewer)
Mar 2024Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)
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Plant Physiology and Biochemistry (Journal)
Ashok IYASWAMY (Reviewer)
Feb 2024 → Apr 2024Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)
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Engineering extracellular vesicles for Alzheimer's disease: An emerging approach for earlier diagnosis and treatment
Ashok IYASWAMY (Speaker)
8 Aug 2023Activity: Conference/talk/lecture/symposium/speech/workshop, etc › Event organized by non-HKBU units
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Press/Media
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HKBU-led research develops novel drug delivery system for Gouteng compound for Alzheimer’s disease treatment
6/12/23
1 item of Media coverage
Press/Media
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HKBU scientists develop versatile compound for treating Alzheimer’s disease
Ashok IYASWAMY, Min LI & Man Shing Wong
24/08/22
1 Media contribution
Press/Media
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HKBU researchers invent Chinese medicine formula for Alzheimer’s disease
3/02/21
1 Media contribution
Press/Media