Projects per year
Personal profile
Chinese Name
關曉儀
Biography
Academic and Professional Qualifications
- B.Sc. (Hons.) degree in Biology, Hong Kong University.
- PhD degree in Physiology, Faculty of Medicine, The Chinese University of Hong Kong.
- Postdoctoral training, Department of Nutritional Sciences & Toxicology, University of California, Berkeley, USA.
- MA degree in Language Studies, The City University of Hong Kong.
Research Works
Dr. Kwan has published over 100 research papers, review articles, editorials, and book chapter in the areas of oncology, obesity, nutrition, and vascular biology in prestigious journals like Proceedings of the National Academy of Sciences of the United States of America (PNAS), Circulation Research, Cell Death and Disease, Journal of Biological Chemistry, Cellular and Molecular Life Sciences, FASEB Journal, Journal of Proteome Research, Molecular Cell, Nature Communication and Cell. Currently, she is an editorial board member for more than 10 international Journals.
Research Interests
Dr. Kwan develops various research platforms to study the roles of small extracellular vesicles (sEVs) in disease development, and the interplay between obesity and cancer. She also discovers novel sEV-based therapeutics to treat cancer, obesity and its comorbid conditions.
Keywords
- RM Therapeutics. Pharmacology
- Obesity
- Cancer
- Exosomes
- Medicinal Herbs
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Development of Zanthoxylum piperitum mature pericarp as health product to control body weight
15/11/21 → 31/08/22
Project: Research project
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WNT974 and artesunate exhibit synergy in inhibiting colorectal cancer growth by increasing KRAS protein degradation
18/02/22 → 17/02/25
Project: Research project
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Integration of Biochemistry and Chinese Medicine to Enhance Students' Learning Experiences
KWAN, H. Y., CHEUNG, K. & TONG, C. K. B.
Project: Teaching project
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Omics approach to reveal the effects of obesity on the protein profiles of the exosomes derived from different adipose depots
Chen, M., Zhang, F., Chen, B., Lau, C., Xu, K., Tong, T., Huo, C., Han, Q., Su, T. & Kwan, H. Y., Nov 2022, In: Cellular and Molecular Life Sciences. 79, 11, 570.Research output: Contribution to journal › Journal article › peer-review
4 Citations (Scopus) -
The impact of obesity on adipocyte-derived extracellular vesicles
Kwan, H. Y., Chen, M., Xu, K. & Chen, B., Dec 2021, In: Cellular and Molecular Life Sciences. 78, 23, p. 7275-7288 14 p.Research output: Contribution to journal › Review article › peer-review
Open Access23 Citations (Scopus) -
Baicalein is a novel TLR4-targeting therapeutics agent that inhibits TLR4/HIF-1α/VEGF signaling pathway in colorectal cancer
Chen, M., Zhong, K., Tan, J., Meng, M. M., Liu, C. M., Chen, B., Huang, C., Wong, H. L. X., Bian, Z., Su, T. & Kwan, H. Y., Nov 2021, In: Clinical and Translational Medicine. 11, 11, e564.Research output: Contribution to journal › Letter › peer-review
Open Access -
Palmitic acid is an intracellular signaling molecule involved in disease development
Fatima, S., Hu, X., Gong, R. H., Huang, C., Chen, M., Wong, H. L. X., Bian, Z. & Kwan, H. Y., 15 Jul 2019, In: Cellular and Molecular Life Sciences. 76, 13, p. 2547-2557 11 p.Research output: Contribution to journal › Review article › peer-review
73 Citations (Scopus) -
Regulation of canonical transient receptor potential isoform 3 (TRPC3) channel by protein kinase G
Kwan, H. Y., Huang, Y. & Yao, X., 24 Feb 2004, In: Proceedings of the National Academy of Sciences of the United States of America. 101, 8, p. 2625-2630 6 p.Research output: Contribution to journal › Journal article › peer-review
Open Access148 Citations (Scopus)
Prizes
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Faculty/ School of Chinese Medicine Performance Award in Teaching 2023
KWAN, Hiu Yee (Recipient), 2023
Prize: Award
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Asia Oceania Association for the Study of Obesity Travel Award
KWAN, Hiu Yee (Recipient), 2 Oct 2015
Prize: Award
Activities
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Role of serum exosomes in mediating enhanced colorectal cancer metastasis under obesity conditions
Hiu Yee KWAN (Speaker)
17 May 2023 → 21 May 2023Activity: Conference/talk/lecture/symposium/speech/workshop, etc › Event organized by non-HKBU units
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15,16-dihydrotanshinone-I-laden PLGA-co-PEG nanoparticles are potential therapeutic agents for the treatment of colorectal cancer by targeting the β-catenin/CD36 axis
Hiu Yee KWAN (Speaker)
13 Mar 2023Activity: Conference/talk/lecture/symposium/speech/workshop, etc › Event organized by non-HKBU units
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IPSCM Annual Meeting
Hiu Yee KWAN (Reviewer)
16 Aug 2022Activity: Conference/talk/lecture/symposium/speech/workshop, etc › Event organized by non-HKBU units
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IPSCM Annual Meeting
Hiu Yee KWAN (Reviewer)
16 Aug 2021Activity: Conference/talk/lecture/symposium/speech/workshop, etc › Event organized by non-HKBU units
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35th Annual Scientific Meeting of the Hong Kong Society of Endocrinology, Metabolism and Reproduction
Hiu Yee KWAN (Reviewer)
4 Nov 2018Activity: Conference/talk/lecture/symposium/speech/workshop, etc › Event organized by non-HKBU units