Projects per year
Personal profile
Chinese Name
關曉儀
Biography
Academic and Professional Qualifications
- B.Sc. (Hons.) degree in Biology, Hong Kong University.
- PhD degree in Physiology, Faculty of Medicine, The Chinese University of Hong Kong.
- Postdoctoral training, Department of Nutritional Sciences & Toxicology, University of California, Berkeley, USA.
- MA degree in Language Studies, The City University of Hong Kong.
- FHEA, HE Advance Fellow
Research Works
Dr. Kwan has published over 100 research papers, review articles, editorials, and book chapter in the areas of oncology, obesity, nutrition, and vascular biology in prestigious journals like Nature Communications, Proceedings of the National Academy of Sciences of the United States of America (PNAS), Cell, Circulation Research, Cell Death and Disease, Journal of Biological Chemistry, Cellular and Molecular Life Sciences, FASEB Journal, Journal of Proteome Research and Molecular Cell. Currently, she is an editorial board member for more than 10 international Journals.
Research Interests
Dr. Kwan is actively involved in developing multiple research platforms dedicated to investigating the roles of small extracellular vesicles (sEVs) in disease development, as well as exploring the intricate relationship between obesity and cancer. Additionally, she has made significant contributions in discovering innovative sEV-based therapeutics for the treatment of cancer, obesity, and related comorbid conditions.
Awards
Dr. Kwan's remarkable achievements have been recognized through several prestigious awards. These include the 中华医学科技奖二等奖 (2020), the HKBU School Performance Award for Young Researcher (2019), as well as Travel Awards to various international conferences in 2015 and 2005. Furthermore, Dr. Kwan was one of the four finalists for the Young Scientist Awards (Life Science) presented by the Institute of Science, Hong Kong in 2005.
Keywords
- RM Therapeutics. Pharmacology
- Obesity
- Cancer
- Exosomes
- Liver disesaes
- Medicinal Herbs
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Development of Zanthoxylum piperitum mature pericarp as health product to control body weight
15/11/21 → 31/08/22
Project: Research project
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Equipment Matching Fund - High-performance Slide Scanner
LIU, J., LI, F., YU, Y., XU, J., FU, X., WONG, H. L. X., KWAN, H. Y. & CHONG, W. P.
26/03/24 → 25/03/26
Project: Research project
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Elevated extracellular matrix protein 1 in circulating extracellular vesicles supports breast cancer progression under obesity conditions
Xu, K., Fu, A., Li, Z., Miao, L., Lou, Z., Jiang, K., Lau, C., Su, T., Tong, T., Bao, J., Lu, A. & Kwan, H. Y., 24 Feb 2024, In: Nature Communications. 15, 1, 17 p., 1685.Research output: Contribution to journal › Journal article › peer-review
Open Access1 Citation (Scopus) -
Omics approach to reveal the effects of obesity on the protein profiles of the exosomes derived from different adipose depots
Chen, M., Zhang, F., Chen, B., Lau, C., Xu, K., Tong, T., Huo, C., Han, Q., Su, T. & Kwan, H. Y., Nov 2022, In: Cellular and Molecular Life Sciences. 79, 11, 570.Research output: Contribution to journal › Journal article › peer-review
8 Citations (Scopus) -
The impact of obesity on adipocyte-derived extracellular vesicles
Kwan, H. Y., Chen, M., Xu, K. & Chen, B., Dec 2021, In: Cellular and Molecular Life Sciences. 78, 23, p. 7275-7288 14 p.Research output: Contribution to journal › Review article › peer-review
Open Access40 Citations (Scopus) -
Baicalein is a novel TLR4-targeting therapeutics agent that inhibits TLR4/HIF-1α/VEGF signaling pathway in colorectal cancer
Chen, M., Zhong, K., Tan, J., Meng, M. M., Liu, C. M., Chen, B., Huang, C., Wong, H. L. X., Bian, Z., Su, T. & Kwan, H. Y., Nov 2021, In: Clinical and Translational Medicine. 11, 11, e564.Research output: Contribution to journal › Letter › peer-review
Open Access -
Signal transducer and activator of transcription-3 drives the high-fat diet-associated prostate cancer growth
Kwan, H. Y., Liu, B., Huang, C., Fatima, S., Su, T., Zhao, X., Ho, A. H. M., Han, Q., Hu, X., Gong, R-H., Chen, M., Wong, H. L. X. & Bian, Z., 2 Sept 2019, In: Cell Death and Disease. 10, 9, 16 p., 637.Research output: Contribution to journal › Journal article › peer-review
Open Access20 Citations (Scopus)
Prizes
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Faculty/ School of Chinese Medicine Performance Award in Teaching 2023
KWAN, Hiu Yee (Recipient), 2023
Prize: Award
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Asia Oceania Association for the Study of Obesity Travel Award
KWAN, Hiu Yee (Recipient), 2 Oct 2015
Prize: Award
Activities
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Role of serum exosomes in mediating enhanced colorectal cancer metastasis under obesity conditions
Hiu Yee KWAN (Speaker)
17 May 2023 → 21 May 2023Activity: Conference/talk/lecture/symposium/speech/workshop, etc › Event organized by non-HKBU units
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15,16-dihydrotanshinone-I-laden PLGA-co-PEG nanoparticles are potential therapeutic agents for the treatment of colorectal cancer by targeting the β-catenin/CD36 axis
Hiu Yee KWAN (Speaker)
13 Mar 2023Activity: Conference/talk/lecture/symposium/speech/workshop, etc › Event organized by non-HKBU units
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IPSCM Annual Meeting
Hiu Yee KWAN (Reviewer)
16 Aug 2022Activity: Conference/talk/lecture/symposium/speech/workshop, etc › Event organized by non-HKBU units
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IPSCM Annual Meeting
Hiu Yee KWAN (Reviewer)
16 Aug 2021Activity: Conference/talk/lecture/symposium/speech/workshop, etc › Event organized by non-HKBU units
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35th Annual Scientific Meeting of the Hong Kong Society of Endocrinology, Metabolism and Reproduction
Hiu Yee KWAN (Reviewer)
4 Nov 2018Activity: Conference/talk/lecture/symposium/speech/workshop, etc › Event organized by non-HKBU units