Projects per year
Personal profile
Chinese Name
Research Interests
Development of anti-Epstein-Barr virus (EBV) inhibitors and imaging agents for nasopharyngeal carcinoma (NPC); Cancer immunology, cancer cachexia and metabolism, and tumor metastasis of NPC; Identification of therapeutic targets and potential drugs for NPC and esophageal squamous cell carcinoma using normal and cancer organoid models.
Biography
Dr. Lung has more than 20 years research experience on translational cancer biology and genomics of nasopharyngeal carcinoma and esophageal squamous cell carcinoma. He has published more than 50 scientific articles and received > 15M research and related grants. As the first and/or corresponding author, he has published 25 scientific articles (which include 21 research papers, 2 review articles, and 2 book chapters) in high impact international journals including Advanced Science (Impact Factor, IF = 15.8, 1 article), Cancer Research (IF = 12.7, 2 articles), JACS Au (IF = 12.35, 1 article), Proc Natl Acad Sci U S A. (IF = 11.2, 1 article), Journal of Experimental & Clinical Cancer Research (IF = 11.16, 1 article), Seminars in Cancer Biology (IF = 9.955, 1 article), Oncogene (IF = 9.867, 3 articles), Nanoscale (IF = 7.79, 1 article), International Journal of Cancer (IF = 7.396, 4 articles), Cancers (IF = 6.639, 1 article), Frontiers in Oncology (IF = 5.66, 1 article), etc.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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ITC Research Talent Hub: related project: Mid-stream Development Of A New Therapeutic (MRP/005/21) Inhibitor For EBV-associated Malignancies
LUNG, H. L. (PI)
2/10/24 → 31/12/25
Project: Research project
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Mid-stream Development Of A New Therapeutic Inhibitor For EBV-associated Malignancies
LUNG, H. L. (PI)
21/03/24 → 31/12/25
Project: Research project
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The application of the EBV-encoded nuclear antigen 1-targeting bioprobe in nasopharyngeal carcinoma diagnosis
LUNG, H. L. (PI) & Cho, W.C.-S. (CoI)
16/03/24 → 15/03/27
Project: Research project
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ITC Research Talent Hub: related project: Mid-stream Development Of A New Therapeutic (MRP/005/21) Inhibitor For EBV-associated Malignancies
LUNG, H. L. (PI)
20/03/23 → 31/12/25
Project: Research project
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ITC Research Talent Hub: related project: Mid-stream Development Of A New Therapeutic (MRP/005/21) Inhibitor For EBV-associated Malignancies
LUNG, H. L. (PI)
20/03/23 → 31/12/25
Project: Research project
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Development of a Modular Ribonucleoprotein Complex as a General Strategy to Deliver RNAi Therapeutics
Tam, N. Y., Wang, X., Chan, G. C. Y., Kong, W. P., Chau, W. Y., Fu, X., Wong, K. Y., Lung, H. L., Yu, Z. L. & Aik, W. S., 26 Sept 2025, In: Advanced Healthcare Materials. 14, 25, 13 p., e03281.Research output: Contribution to journal › Journal article › peer-review
Open Access -
Hypomethylation of thrombospondin-1 promoter region is associated with reduced aqueous humor flow
Choy, K. Y., Yang, W. Y., Ling, C. Y., Li, K. K., Li, H. L., Lung, H. L., To, C. H., Do, C. W., Stamer, W. D. & Shan, S. S. W., 6 Oct 2025, In: Communications Biology. 8, 1, 10 p., 1430.Research output: Contribution to journal › Journal article › peer-review
Open Access -
Abstract 5786: Epstein-Barr virus nuclear antigen 1 (EBNA1)-targeting probes stimulate interferon-β production by nasopharyngeal carcinoma (NPC) cells to enhance the natural killer cell-mediated cytotoxicity against NPC
Chen, L., Liu, X. H., Yuen, H. T., Cho, W. C., Wong, K.-L. & Lung, H. L., 15 Mar 2024, In: Cancer Research. 84, 6, Supplement, 1 p., 5786.Research output: Contribution to journal › Conference article › peer-review
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EBNA1-targeting probes stimulate interferon-β production by NPC cells to enhance the natural killer cell-mediated cytotoxicity against NPC
Lung, H. L., Liu, X., Yuen, H. T., Cho, W.C.-S. & Wong, K.-L., 1 Jun 2024.Research output: Contribution to conference › Conference paper › peer-review
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EBNA1 inhibitors with lytic induction activity can sensitize natural killer cells to mediate the killing of nasopharyngeal carcinoma cells
Lung, H. L. & Chen, L., 15 Apr 2023.Research output: Contribution to conference › Conference paper
Prizes
Activities
- 2 Editor/reviewer for publications (incl. CDCF T61 Journal Editor)
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Experimental Cell Research (Journal)
LUNG, H. L. (Reviewer)
2025 → …Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)
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Bio-protocol (Journal)
LUNG, H. L. (Associate editor)
2013Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)