Projects per year
Personal profile
Chinese Name
Research Interests
Development of anti-Epstein-Barr virus (EBV) inhibitors and imaging agents for nasopharyngeal carcinoma (NPC); Cancer immunology, cancer cachexia and metabolism, and tumor metastasis of NPC; Identification of therapeutic targets and potential drugs for NPC and esophageal squamous cell carcinoma using normal and cancer organoid models.
Biography
Dr. Lung has more than 20 years research experience on translational cancer biology and genomics of nasopharyngeal carcinoma and esophageal squamous cell carcinoma. He has published more than 50 scientific articles and received > 15M research and related grants. As the first and/or corresponding author, he has published 25 scientific articles (which include 21 research papers, 2 review articles, and 2 book chapters) in high impact international journals including Advanced Science (Impact Factor, IF = 15.8, 1 article), Cancer Research (IF = 12.7, 2 articles), JACS Au (IF = 12.35, 1 article), Proc Natl Acad Sci U S A. (IF = 11.2, 1 article), Journal of Experimental & Clinical Cancer Research (IF = 11.16, 1 article), Seminars in Cancer Biology (IF = 9.955, 1 article), Oncogene (IF = 9.867, 3 articles), Nanoscale (IF = 7.79, 1 article), International Journal of Cancer (IF = 7.396, 4 articles), Cancers (IF = 6.639, 1 article), Frontiers in Oncology (IF = 5.66, 1 article), etc.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Mid-stream Development Of A New Therapeutic Inhibitor For EBV-associated Malignancies
21/03/24 → 31/12/25
Project: Research project
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The application of the EBV-encoded nuclear antigen 1-targeting bioprobe in nasopharyngeal carcinoma diagnosis
LUNG, H. L. & Cho, W. C.
16/03/24 → 15/03/27
Project: Research project
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The use of natural killer cells as therapeutic agents in nasopharyngeal carcinoma
6/04/20 → 5/04/23
Project: Research project
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BP InnoMed Limited
LI, W. S., LUNG, H. L. & WONG, K.
1/04/19 → 31/03/22
Project: Knowledge transfer project
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The epithelial SAA1 protein regulates Epithelial-Mesenchymal-Transition (EMT) in normal esophageal epithelium and esophageal carcinoma
1/07/17 → 31/12/20
Project: Research project
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EBV latent membrane protein 1 augments γδ T cell cytotoxicity against nasopharyngeal carcinoma by induction of butyrophilin molecules
Liu, Y., Lui, K. S., Ye, Z., Fung, T. Y., Chen, L., Sit, P. Y., Leung, C. Y., Mak, N. K., Wong, K. L., Lung, H. L., Tanaka, Y. & Cheung, A. K. L., Jan 2023, In: Theranostics. 13, 2, p. 458-471 14 p.Research output: Contribution to journal › Journal article › peer-review
Open Access5 Citations (Scopus) -
THY1 (CD90) Maintains the Adherens Junctions in Nasopharyngeal Carcinoma via Inhibition of SRC Activation
Chen, L., Chau, W. Y., Yuen, H. T., Liu, X. H., Qi, R. Z., Lung, M. L. & Lung, H. L., 1 Apr 2023, In: Cancers. 15, 7, 17 p., 2189.Research output: Contribution to journal › Journal article › peer-review
Open Access1 Citation (Scopus) -
The CBP/β-Catenin Antagonist, ICG-001, Inhibits Tumor Metastasis via Blocking of the miR-134/ITGB1 Axis-Mediated Cell Adhesion in Nasopharyngeal Carcinoma
Chen, L., Chiang, Y. C., Chan, L. S., Chau, W. Y., Lung, M. L., Kahn, M., Lo, K. W., Mak, N. K. & Lung, H. L., 1 Jul 2022, In: Cancers. 14, 13, 3125.Research output: Contribution to journal › Journal article › peer-review
Open AccessFile6 Citations (Scopus)65 Downloads (Pure) -
Design, synthesis and comparison of water-soluble phthalocyanine/porphyrin analogues and their inhibition effects on Aβ42fibrillization
Xu, W., Gao, C., Sun, X., Tai, W. C. S., Lung, H. L. & Law, G. L., 21 Jul 2021, In: Inorganic Chemistry Frontiers. 8, 14, p. 3501-3513 13 p.Research output: Contribution to journal › Journal article › peer-review
6 Citations (Scopus) -
Dual-Targeting Peptide-Guided Approach for Precision Delivery and Cancer Monitoring by Using a Safe Upconversion Nanoplatform
Zha, S., Chau, H. F., Chau, W. Y., Chan, L. S., Lin, J., Lo, K. W., Chi-Shing Cho, W., Yip, Y. L., Tsao, S. W., Farrell, P. J., Feng, L., Di, J. M., Law, G. L., Lung, H. L. & Wong, K-L., 3 Mar 2021, In: Advanced Science. 8, 5, 15 p., 2002919.Research output: Contribution to journal › Journal article › peer-review
Open Access57 Citations (Scopus)