Research output per year
Research output per year
- 34 results
Search results
-
2024
A cross-disease, pleiotropy-driven approach for therapeutic target prioritization and evaluation
Bao, C., Tan, T., Wang, S., Gao, C., Lu, C., Yang, S., Diao, Y., Jiang, L., Jing, D., Chen, L., Lv, H. & Fang, H., 22 Apr 2024, In: Cell Reports Methods. 4, 4, 21 p., 100757.Research output: Contribution to journal › Journal article › peer-review
Open AccessFile1 Citation (Scopus)37 Downloads (Pure) -
Artificial intelligence with mass spectrometry-based multimodal molecular profiling methods for advancing therapeutic discovery of infectious diseases
Liu, J., Bao, C., Zhang, J., Han, Z., Fang, H. & Lu, H., Nov 2024, In: Pharmacology and Therapeutics. 263, 108712.Research output: Contribution to journal › Journal article › peer-review
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Mineral crude drug mirabilite (Mangxiao) inhibits the occurrence of colorectal cancer by regulating the Lactobacillus–bile acid–intestinal farnesoid X receptor axis based on multiomics integration analysis
Zhou, X., Sun, H., Ren, J., Yan, G., Yang, L., Zhang, H., Lu, H., Li, X., Makino, T., Yin, F., Li, J. & Wang, X., May 2024, In: MedComm. 5, 5, p. e556 18 p., e556.Research output: Contribution to journal › Journal article › peer-review
Open AccessFile25 Downloads (Pure) -
2023
Functional metabolomics revealed the dual-activation of cAMP-AMP axis is a novel therapeutic target of pancreatic cancer
Liu, J., Jing, W., Wang, T., Hu, Z. & Lu, H., Jan 2023, In: Pharmacological Research. 187, 11 p., 106554.Research output: Contribution to journal › Journal article › peer-review
Open Access8 Citations (Scopus) -
2022
Functional metabolomics revealed functional metabolic-characteristics of chronic hepatitis that is significantly differentiated from acute hepatitis in mice
Wang, T., Hu, L., Lu, J., Xiao, M., Liu, J., Xia, H. & Lu, H., Jun 2022, In: Pharmacological Research. 180, 106248.Research output: Contribution to journal › Journal article › peer-review
9 Citations (Scopus) -
Mass Spectrometry-Based Targeted Metabolomics Revealed the Regulatory Roles of Magnesium on Biofilm Formation in Escherichia coli by Targeting Functional Metabolites
Wang, T-Y., Guo, R., Hu, L-L., Liu, J-J. & Lu, H-T., Jun 2022, In: Journal of Analysis and Testing. 6, 2, p. 89-97 9 p.Research output: Contribution to journal › Journal article › peer-review
6 Citations (Scopus) -
2021
Berberine improves colitis by triggering AhR activation by microbial tryptophan catabolites
Jing, W., Dong, S., Luo, X., Liu, J., Wei, B., Du, W., Yang, L., Luo, H., WANG, Y., Wang, S. & Lu, H., Feb 2021, In: Pharmacological Research. 164, 105358.Research output: Contribution to journal › Journal article › peer-review
113 Citations (Scopus) -
Dihydromyricetin improves DSS-induced colitis in mice via modulation of fecal-bacteria-related bile acid metabolism
Dong, S., Zhu, M., Wang, K., Zhao, X., Hu, L., Jing, W., Lu, H. & Wang, S., Sept 2021, In: Pharmacological Research. 171, 105767.Research output: Contribution to journal › Journal article › peer-review
97 Citations (Scopus) -
Functional metabolomics innovates therapeutic discovery of traditional Chinese medicine derived functional compounds
Wang, T., Liu, J., Luo, X., Hu, L. & Lu, H., Aug 2021, In: Pharmacology and Therapeutics. 224, 107824.Research output: Contribution to journal › Journal article › peer-review
49 Citations (Scopus) -
Mass spectrometry based targeted metabolomics precisely characterized new functional metabolites that regulate biofilm formation in Escherichia coli
Guo, R., Luo, X., Liu, J. & Lu, H., 8 Feb 2021, In: Analytica Chimica Acta. 1145, p. 26-36 11 p.Research output: Contribution to journal › Journal article › peer-review
25 Citations (Scopus) -
Precision-characterization and quantitative determination of main compounds in Si-Ni-San with UHPLC-MS/MS based targeted-profiling method
Tian, T., Xu, X., Li, X., Zhang, W. & Lu, H., 5 Feb 2021, In: Journal of Pharmaceutical and Biomedical Analysis. 194, 113816.Research output: Contribution to journal › Journal article › peer-review
8 Citations (Scopus) -
2020
Cell Metabolomics Reveals Berberine-Inhibited Pancreatic Cancer Cell Viability and Metastasis by Regulating Citrate Metabolism
Liu, J., Luo, X., Guo, R., Jing, W. & Lu, H., 4 Sept 2020, In: Journal of Proteome Research. 19, 9, p. 3825-3836 12 p.Research output: Contribution to journal › Journal article › peer-review
44 Citations (Scopus) -
Functional Metabolomics Decipher Biochemical Functions And Associated Mechanisms Underlie Small-Molecule Metabolism
Hu, L., Liu, J., Zhang, W., Wang, T., Zhang, N., Lee, Y. H. & LYU, H., Sept 2020, In: Mass Spectrometry Reviews. 39, 5-6, p. 417-433 17 p.Research output: Contribution to journal › Journal article › peer-review
54 Citations (Scopus) -
Metabolomics identified new biomarkers for the precise diagnosis of pancreatic cancer and associated tissue metastasis
Luo, X., Liu, J., Wang, H. & Lu, H., Jun 2020, In: Pharmacological Research. 156, 104805.Research output: Contribution to journal › Journal article › peer-review
61 Citations (Scopus) -
Targeted Metabolomics Revealed the Regulatory Role of Manganese on Small-Molecule Metabolism of Biofilm Formation in Escherichia coli
Guo, R. & Lu, H., Jul 2020, In: Journal of Analysis and Testing. 4, 3, p. 226-237 12 p.Research output: Contribution to journal › Journal article › peer-review
11 Citations (Scopus) -
2019
Metabolomics Assay Identified a Novel Virulence-Associated Siderophore Encoded by the High-Pathogenicity Island in Uropathogenic Escherichia coli
Xu, G., Guo, H. & Lv, H., May 2019, In: Journal of Proteome Research. 18, 5, p. 2331-2336 6 p.Research output: Contribution to journal › Journal article › peer-review
10 Citations (Scopus) -
Metabolomics Deciphered Metabolic Reprogramming Required for Biofilm Formation
Lu, H., Que, Y., Wu, X., Guan, T. & Guo, H., Sept 2019, In: Scientific Reports. 9, 7 p., 13160.Research output: Contribution to journal › Journal article › peer-review
Open Access43 Citations (Scopus) -
2018
Mass spectrometry-derived systems biology technologies delineate the system's biochemical applications of siderophores.
Su, Q., Xu, G., Guan, T., Que, Y. & Lu, H., Mar 2018, In: Mass Spectrometry Reviews. 37, 2, p. 188-201 13 p.Research output: Contribution to journal › Journal article › peer-review
8 Citations (Scopus) -
2016
Siderophore biosynthesis coordinately modulated the virulence-associated interactive metabolome of uropathogenic Escherichia coli and human urine
Su, Q., Guan, T. & Lv, H., 14 Apr 2016, In: Scientific Reports. 6, 11 p., 24099.Research output: Contribution to journal › Journal article › peer-review
Open Access23 Citations (Scopus) -
Siderophore Biosynthesis Governs the Virulence of Uropathogenic Escherichia coli by Coordinately Modulating the Differential Metabolism
Su, Q., Guan, T., He, Y. & Lv, H., Apr 2016, In: Journal of Proteome Research. 15, 4, p. 1323-1332 10 p.Research output: Contribution to journal › Journal article › peer-review
20 Citations (Scopus) -
2015
Metabolic phenotyping of the Yersinia high-pathogenicity island that regulates central carbon metabolism
Yan, L., Nie, W. & Lv, H., May 2015, In: Analyst. 140, 10, p. 3356-3361 6 p.Research output: Contribution to journal › Journal article › peer-review
17 Citations (Scopus) -
Prediction and Characterisation of the System Effects of Aristolochic Acid: A Novel Joint Network Analysis towards Therapeutic and Toxicological Mechanisms
Nie, W., Lv, Y., Yan, L., Chen, X. & Lv, H., Dec 2015, In: Scientific Reports. 5, 13 p., 17646.Research output: Contribution to journal › Journal article › peer-review
Open Access14 Citations (Scopus) -
2014
Metabolite profiling and pathway analysis of acute hepatitis rats by UPLC-ESI MS combined with pattern recognition methods
Wang, X., Lv, H., Zhang, A., Sun, W., Liu, L., Wang, P., Wu, Z., Zou, D. & Sun, H., May 2014, In: Liver International. 34, 5, p. 759-770 12 p.Research output: Contribution to journal › Journal article › peer-review
30 Citations (Scopus) -
Metabolomic Analysis of Siderophore Cheater Mutants Reveals Metabolic Costs of Expression in Uropathogenic Escherichia coli
Lv, H., Hung, C. S. & Henderson, J. P., Mar 2014, In: Journal of Proteome Research. 13, 3, p. 1397-1404 8 p.Research output: Contribution to journal › Journal article › peer-review
41 Citations (Scopus) -
2013
Improved ultra-performance liquid chromatography with electrospray ionization quadrupole-time-of-flight high-definition mass spectrometry method for the rapid analysis of the chemical constituents of a typical medical formula: Liuwei Dihuang Wan
Wang, P., Lv, H. T., Zhang, A. H., Sun, H., Yan, G. L., Han, Y., Wu, X. H. & Wang, X. J., Nov 2013, In: Journal of Separation Science. 36, 21-22, p. 3511-3516 6 p.Research output: Contribution to journal › Journal article › peer-review
27 Citations (Scopus) -
Metabolomics coupled with proteomics advancing drug discovery toward more agile development of targeted combination therapies
Wang, X., Zhang, A., Wang, P., Sun, H., Wu, G., Sun, W., Lv, H., Jiao, G., Xu, H., Yuan, Y., Liu, L., Zou, D., Wu, Z., Han, Y., Yan, G., Dong, W., Wu, F., Dong, T., Yu, Y., Zhang, S., & 3 others, May 2013, In: Molecular and Cellular Proteomics. 12, 5, p. 1226-1238 13 p.Research output: Contribution to journal › Journal article › peer-review
Open Access144 Citations (Scopus) -
2011
Advantages of Tandem LC−MS for the Rapid Assessment of Tissue-Specific Metabolic Complexity Using a Pentafluorophenylpropyl Stationary Phase
Lv, H., Palacios, G., Hartil, K. & Kurland, I. J., Apr 2011, In: Journal of Proteome Research. 10, 4, p. 2104-2112 9 p.Research output: Contribution to journal › Journal article › peer-review
31 Citations (Scopus) -
Development of an integrated metabolomic profiling approach for infectious diseases research
Lv, H., Hung, C. S., Chaturvedi, K. S., Hooton, T. M. & Henderson, J. P., 21 Nov 2011, In: Analyst. 136, 22, p. 4752-4763 12 p.Research output: Contribution to journal › Journal article › peer-review
39 Citations (Scopus) -
Metabolomic analysis characterizes tissue specific indomethacin-induced metabolic perturbations of rats
Lv, H., Liu, L., Palacios, G. & Chen, X., Jun 2011, In: Analyst. 136, 11, p. 2260-2269 10 p.Research output: Contribution to journal › Journal article › peer-review
7 Citations (Scopus) -
Yersinia high pathogenicity Island genes modify the Escherichia coli primary metabolome independently of siderophore production
Lv, H. & Henderson, J. P., Dec 2011, In: Journal of Proteome Research. 10, 12, p. 5547-5554 8 p.Research output: Contribution to journal › Journal article › peer-review
24 Citations (Scopus) -
2010
Pharmacokinetics-based elucidation on disparity in clinical effectiveness between varieties of Zhi Zhu Wan, a Traditional Chinese Medical formula
Cao, H., Chen, X., Sun, H., Sakurai, T., Zhou, J., Sun, W., Lv, H. & Wang, X., Apr 2010, In: Journal of Ethnopharmacology. 128, 3, p. 606-610 5 p.Research output: Contribution to journal › Journal article › peer-review
17 Citations (Scopus) -
Plasma metabolomics reveals biomarkers of the atherosclerosis
Chen, X., Liu, L., Palacios, G., Gao, J., Zhang, N., Li, G., Lu, J., Song, T., Zhang, Y. & Lv, H., Sept 2010, In: Journal of Separation Science. 33, 17-18, p. 2776-2783 8 p.Research output: Contribution to journal › Journal article › peer-review
73 Citations (Scopus) -
Thyroxine and reserpine-induced changes in metabolic profiles of rat urine and the therapeutic effect of Liu Wei Di Huang Wan detected by UPLC-HDMS
Wang, P., Sun, H., Lv, H., Sun, W., Yuan, Y., Han, Y., Wang, D., Zhang, A. & Wang, X., Nov 2010, In: Journal of Pharmaceutical and Biomedical Analysis. 53, 3, p. 631-645 15 p.Research output: Contribution to journal › Journal article › peer-review
86 Citations (Scopus) -
2008
Pharmacokinetic studies of a Chinese triple herbal drug formula
Lv, H., Sun, H., Sun, W., Liu, L., Wang, P., Wang, X. & Cao, H., Nov 2008, In: Phytomedicine. 15, 11, p. 993 - 1001 9 p.Research output: Contribution to journal › Journal article › peer-review
34 Citations (Scopus)