Research output per year
Research output per year
- 50 results
Search results
-
2025
Development of a liquid chromatography–mass spectrometry based targeted metabolomics method for discovering diagnostic biomarkers in Kawasaki disease
Luo, X., Tian, J., Li, Q., Jin, Z., Fan, X., Zhang, H., Lv, H. & Ju, Y., 25 Jan 2025, In: Journal of Chromatography A. 1741, 9 p., 465619.Research output: Contribution to journal › Journal article › peer-review
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Gut Microbiota-associated Metabolites Affected the Susceptibility to Heart Health Abnormality in Young Migrants at High-altitude
Zhou, Y., Ni, Z., Liu, J., Sun, D., Chen, X., Shen, P., Li, G., Bai, Z., Hu, Y., Wang, N., Wang, R., Guan, L., Wang, Y., Tang, X., He, B., Lu, H., Zhou, W. & Gao, Y., 28 Jan 2025, (Accepted/In press) In: Exploration.Research output: Contribution to journal › Journal article › peer-review
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Gut microbiota-derived tryptophan metabolites regulated by Wuji Wan to attenuate colitis through AhR signaling activation
Jing, W., Dong, S., Xu, Y., Liu, J., Ren, J., Liu, X., Zhu, M., Zhang, M., Shi, H., Li, N., Xia, P., Lu, H. & Wang, S., Jan 2025, In: Acta Pharmaceutica Sinica B. 15, 1, p. 205-223 19 p.Research output: Contribution to journal › Journal article › peer-review
Open Access2 Citations (Scopus) -
Plasma Proteomic Profiling Reveals ITGA2B as A Key Regulator of Heart Health in High-altitude Settlers
Wang, Y., Shen, P., Wu, Z., Tu, B., Zhang, C., Zhou, Y., Liu, Y., Wang, G., Bai, Z., Tang, X., Lai, C., Lu, H., Zhou, W. & Gao, Y., 8 Apr 2025, (E-pub ahead of print) In: Genomics, Proteomics and Bioinformatics. 44 p., qzaf030.Research output: Contribution to journal › Journal article › peer-review
Open Access -
2024
A cross-disease, pleiotropy-driven approach for therapeutic target prioritization and evaluation
Bao, C., Tan, T., Wang, S., Gao, C., Lu, C., Yang, S., Diao, Y., Jiang, L., Jing, D., Chen, L., Lv, H. & Fang, H., 22 Apr 2024, In: Cell Reports Methods. 4, 4, 21 p., 100757.Research output: Contribution to journal › Journal article › peer-review
Open AccessFile3 Citations (Scopus)39 Downloads (Pure) -
Artificial intelligence with mass spectrometry-based multimodal molecular profiling methods for advancing therapeutic discovery of infectious diseases
Liu, J., Bao, C., Zhang, J., Han, Z., Fang, H. & Lu, H., Nov 2024, In: Pharmacology and Therapeutics. 263, 108712.Research output: Contribution to journal › Journal article › peer-review
1 Citation (Scopus) -
Mineral crude drug mirabilite (Mangxiao) inhibits the occurrence of colorectal cancer by regulating the Lactobacillus–bile acid–intestinal farnesoid X receptor axis based on multiomics integration analysis
Zhou, X., Sun, H., Ren, J., Yan, G., Yang, L., Zhang, H., Lu, H., Li, X., Makino, T., Yin, F., Li, J. & Wang, X., May 2024, In: MedComm. 5, 5, p. e556 18 p., e556.Research output: Contribution to journal › Journal article › peer-review
Open AccessFile2 Citations (Scopus)31 Downloads (Pure) -
Zhishi Xiebai Guizhi Decoction modulates hypoxia and lipid toxicity to alleviate pulmonary vascular remodeling of pulmonary hypertension in rats
Fu, M., Li, Y., Liu, J., Liu, J., Wei, J., Qiao, Y., Zhong, H., Han, D., Lu, H. & Yao, L., Dec 2024, In: Chinese Medicine. 19, 1, 18 p., 173.Research output: Contribution to journal › Journal article › peer-review
Open Access -
2023
Functional metabolomics revealed the dual-activation of cAMP-AMP axis is a novel therapeutic target of pancreatic cancer
Liu, J., Jing, W., Wang, T., Hu, Z. & Lu, H., Jan 2023, In: Pharmacological Research. 187, 11 p., 106554.Research output: Contribution to journal › Journal article › peer-review
Open Access11 Citations (Scopus) -
2022
Emerging pharmacotherapy for inflammatory bowel diseases
Luo, H., Cao, G., Luo, C., Tan, D., Vong, C. T., Xu, Y., Wang, S., Lu, H., Wang, Y. & Jing, W., Apr 2022, In: Pharmacological Research. 178, 106146.Research output: Contribution to journal › Review article › peer-review
68 Citations (Scopus) -
Functional metabolomics revealed functional metabolic-characteristics of chronic hepatitis that is significantly differentiated from acute hepatitis in mice
Wang, T., Hu, L., Lu, J., Xiao, M., Liu, J., Xia, H. & Lu, H., Jun 2022, In: Pharmacological Research. 180, 106248.Research output: Contribution to journal › Journal article › peer-review
11 Citations (Scopus) -
Mass Spectrometry-Based Targeted Metabolomics Revealed the Regulatory Roles of Magnesium on Biofilm Formation in Escherichia coli by Targeting Functional Metabolites
Wang, T.-Y., Guo, R., Hu, L.-L., Liu, J.-J. & Lu, H.-T., Jun 2022, In: Journal of Analysis and Testing. 6, 2, p. 89-97 9 p.Research output: Contribution to journal › Journal article › peer-review
9 Citations (Scopus) -
2021
Berberine improves colitis by triggering AhR activation by microbial tryptophan catabolites
Jing, W., Dong, S., Luo, X., Liu, J., Wei, B., Du, W., Yang, L., Luo, H., WANG, Y., Wang, S. & Lu, H., Feb 2021, In: Pharmacological Research. 164, 105358.Research output: Contribution to journal › Journal article › peer-review
144 Citations (Scopus) -
Dihydromyricetin improves DSS-induced colitis in mice via modulation of fecal-bacteria-related bile acid metabolism
Dong, S., Zhu, M., Wang, K., Zhao, X., Hu, L., Jing, W., Lu, H. & Wang, S., Sept 2021, In: Pharmacological Research. 171, 105767.Research output: Contribution to journal › Journal article › peer-review
132 Citations (Scopus) -
Functional metabolomics innovates therapeutic discovery of traditional Chinese medicine derived functional compounds
Wang, T., Liu, J., Luo, X., Hu, L. & Lu, H., Aug 2021, In: Pharmacology and Therapeutics. 224, 107824.Research output: Contribution to journal › Journal article › peer-review
59 Citations (Scopus) -
Mass spectrometry based targeted metabolomics precisely characterized new functional metabolites that regulate biofilm formation in Escherichia coli
Guo, R., Luo, X., Liu, J. & Lu, H., 8 Feb 2021, In: Analytica Chimica Acta. 1145, p. 26-36 11 p.Research output: Contribution to journal › Journal article › peer-review
29 Citations (Scopus) -
Microbial Metabolomics: From Methods to Translational Applications
Guo, R., Luo, X., Xin, X., Liu, L., Wang, X. & Lu, H., 1 Apr 2021, Cancer Metabolomics: Methods and Applications. Hu, S. (ed.). 1 ed. Springer Cham, p. 97-113 17 p. (Advances in Experimental Medicine and Biology; vol. 1280).Research output: Chapter in book/report/conference proceeding › Chapter › peer-review
4 Citations (Scopus) -
Precision-characterization and quantitative determination of main compounds in Si-Ni-San with UHPLC-MS/MS based targeted-profiling method
Tian, T., Xu, X., Li, X., Zhang, W. & Lu, H., 5 Feb 2021, In: Journal of Pharmaceutical and Biomedical Analysis. 194, 113816.Research output: Contribution to journal › Journal article › peer-review
10 Citations (Scopus) -
2020
Cell Metabolomics Reveals Berberine-Inhibited Pancreatic Cancer Cell Viability and Metastasis by Regulating Citrate Metabolism
Liu, J., Luo, X., Guo, R., Jing, W. & Lu, H., 4 Sept 2020, In: Journal of Proteome Research. 19, 9, p. 3825-3836 12 p.Research output: Contribution to journal › Journal article › peer-review
53 Citations (Scopus) -
Functional Metabolomics Decipher Biochemical Functions And Associated Mechanisms Underlie Small-Molecule Metabolism
Hu, L., Liu, J., Zhang, W., Wang, T., Zhang, N., Lee, Y. H. & LYU, H., Sept 2020, In: Mass Spectrometry Reviews. 39, 5-6, p. 417-433 17 p.Research output: Contribution to journal › Journal article › peer-review
59 Citations (Scopus) -
Metabolomics identified new biomarkers for the precise diagnosis of pancreatic cancer and associated tissue metastasis
Luo, X., Liu, J., Wang, H. & Lu, H., Jun 2020, In: Pharmacological Research. 156, 104805.Research output: Contribution to journal › Journal article › peer-review
72 Citations (Scopus) -
Omics strategies decipher therapeutic discoveries of traditional Chinese medicine against different diseases at multiple layers molecular-level
Guo, R., Luo, X., Liu, J., Liu, L., Wang, X. & Lu, H., Feb 2020, In: Pharmacological Research. 152, 104627.Research output: Contribution to journal › Review article › peer-review
89 Citations (Scopus) -
Targeted Metabolomics Revealed the Regulatory Role of Manganese on Small-Molecule Metabolism of Biofilm Formation in Escherichia coli
Guo, R. & Lu, H., Jul 2020, In: Journal of Analysis and Testing. 4, 3, p. 226-237 12 p.Research output: Contribution to journal › Journal article › peer-review
11 Citations (Scopus) -
2019
Mass spectrometry and associated technologies delineate the advantageously biomedical capacity of siderophores in different pathogenic contexts
Luo, X., Guo, R., Xu, X., Li, X., Yao, L., Wang, X. & Lu, H., 1 May 2019, In: Mass Spectrometry Reviews. 38, 3, p. 239-252 14 p.Research output: Contribution to journal › Review article › peer-review
10 Citations (Scopus) -
Metabolomics Assay Identified a Novel Virulence-Associated Siderophore Encoded by the High-Pathogenicity Island in Uropathogenic Escherichia coli
Xu, G., Guo, H. & Lv, H., May 2019, In: Journal of Proteome Research. 18, 5, p. 2331-2336 6 p.Research output: Contribution to journal › Journal article › peer-review
11 Citations (Scopus) -
Metabolomics Deciphered Metabolic Reprogramming Required for Biofilm Formation
Lu, H., Que, Y., Wu, X., Guan, T. & Guo, H., Sept 2019, In: Scientific Reports. 9, 7 p., 13160.Research output: Contribution to journal › Journal article › peer-review
Open Access48 Citations (Scopus) -
2018
Challenges and emergent solutions for LC-MS/MS based untargeted metabolomics in diseases
Cui, L., Lu, H. & Lee, Y. H., Nov 2018, In: Mass Spectrometry Reviews. 37, 6, p. 772-792 21 p.Research output: Contribution to journal › Review article › peer-review
290 Citations (Scopus) -
Mass spectrometry-derived systems biology technologies delineate the system's biochemical applications of siderophores.
Su, Q., Xu, G., Guan, T., Que, Y. & Lu, H., Mar 2018, In: Mass Spectrometry Reviews. 37, 2, p. 188-201 13 p.Research output: Contribution to journal › Journal article › peer-review
8 Citations (Scopus) -
2016
Advanced mass spectrometry-based multi-omics technologies for exploring the pathogenesis of hepatocellular carcinoma
Nie, W., Yan, L., Lee, Y. H., Guha, C., Kurland, I. J. & Lu, H., May 2016, In: Mass Spectrometry Reviews. 35, 3, p. 331-349 19 p.Research output: Contribution to journal › Review article › peer-review
38 Citations (Scopus) -
Siderophore biosynthesis coordinately modulated the virulence-associated interactive metabolome of uropathogenic Escherichia coli and human urine
Su, Q., Guan, T. & Lv, H., 14 Apr 2016, In: Scientific Reports. 6, 11 p., 24099.Research output: Contribution to journal › Journal article › peer-review
Open Access25 Citations (Scopus) -
Siderophore Biosynthesis Governs the Virulence of Uropathogenic Escherichia coli by Coordinately Modulating the Differential Metabolism
Su, Q., Guan, T., He, Y. & Lv, H., Apr 2016, In: Journal of Proteome Research. 15, 4, p. 1323-1332 10 p.Research output: Contribution to journal › Journal article › peer-review
20 Citations (Scopus) -
The biochemistry of blister fluid from pediatric burn injuries: Proteomics and metabolomics aspects
Zang, T., Broszczak, D. A., Broadbent, J. A., Cuttle, L., Lu, H. & Parker, T. J., Jan 2016, In: Expert Review of Proteomics. 13, 1, p. 35-53 19 p.Research output: Contribution to journal › Review article › peer-review
13 Citations (Scopus) -
2015
Metabolic Biomarkers of Alcohol Liver Damage and the Intervention Effect of Yinchenhao Tang
Sun, H., Lv, H., Zhang, A. & Wang, X., 17 Jul 2015, Chinmedomics: The Integration of Serum Pharmacochemistry and Metabolomics to Elucidate the Scientific Value of Traditional Chinese Medicine. Wang, X., Zhang, A. & Sun, H. (eds.). Academic Press, p. 293-304 12 p.Research output: Chapter in book/report/conference proceeding › Chapter › peer-review
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Metabolic phenotyping of the Yersinia high-pathogenicity island that regulates central carbon metabolism
Yan, L., Nie, W. & Lv, H., May 2015, In: Analyst. 140, 10, p. 3356-3361 6 p.Research output: Contribution to journal › Journal article › peer-review
17 Citations (Scopus) -
Metabolic Profiling of Healthy Persons Treated with Liuweidihuang Wan
Wang, X., Lv, H., Sun, H. & Zhang, A., 17 Jul 2015, Chinmedomics: The Integration of Serum Pharmacochemistry and Metabolomics to Elucidate the Scientific Value of Traditional Chinese Medicine. Wang, X., Zhang, A. & Sun, H. (eds.). Academic Press, p. 195-205 11 p.Research output: Chapter in book/report/conference proceeding › Chapter › peer-review
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Prediction and Characterisation of the System Effects of Aristolochic Acid: A Novel Joint Network Analysis towards Therapeutic and Toxicological Mechanisms
Nie, W., Lv, Y., Yan, L., Chen, X. & Lv, H., Dec 2015, In: Scientific Reports. 5, 13 p., 17646.Research output: Contribution to journal › Journal article › peer-review
Open Access14 Citations (Scopus) -
2014
Metabolite profiling and pathway analysis of acute hepatitis rats by UPLC-ESI MS combined with pattern recognition methods
Wang, X., Lv, H., Zhang, A., Sun, W., Liu, L., Wang, P., Wu, Z., Zou, D. & Sun, H., May 2014, In: Liver International. 34, 5, p. 759-770 12 p.Research output: Contribution to journal › Journal article › peer-review
31 Citations (Scopus) -
Metabolomic Analysis of Siderophore Cheater Mutants Reveals Metabolic Costs of Expression in Uropathogenic Escherichia coli
Lv, H., Hung, C. S. & Henderson, J. P., Mar 2014, In: Journal of Proteome Research. 13, 3, p. 1397-1404 8 p.Research output: Contribution to journal › Journal article › peer-review
42 Citations (Scopus) -
2013
Improved ultra-performance liquid chromatography with electrospray ionization quadrupole-time-of-flight high-definition mass spectrometry method for the rapid analysis of the chemical constituents of a typical medical formula: Liuwei Dihuang Wan
Wang, P., Lv, H. T., Zhang, A. H., Sun, H., Yan, G. L., Han, Y., Wu, X. H. & Wang, X. J., Nov 2013, In: Journal of Separation Science. 36, 21-22, p. 3511-3516 6 p.Research output: Contribution to journal › Journal article › peer-review
27 Citations (Scopus) -
Mass spectrometry-based metabolomics towards understanding of gene functions with a diversity of biological contexts
Lv, H., Mar 2013, In: Mass Spectrometry Reviews. 32, 2, p. 118-128 11 p.Research output: Contribution to journal › Review article › peer-review
26 Citations (Scopus) -
Metabolomics coupled with proteomics advancing drug discovery toward more agile development of targeted combination therapies
Wang, X., Zhang, A., Wang, P., Sun, H., Wu, G., Sun, W., Lv, H., Jiao, G., Xu, H., Yuan, Y., Liu, L., Zou, D., Wu, Z., Han, Y., Yan, G., Dong, W., Wu, F., Dong, T., Yu, Y. & Zhang, S. & 3 others, , May 2013, In: Molecular and Cellular Proteomics. 12, 5, p. 1226-1238 13 p.Research output: Contribution to journal › Journal article › peer-review
Open Access146 Citations (Scopus) -
MS-based metabolomics facilitates the discovery of in vivo functional small molecules with a diversity of biological contexts
Yan, L., Nie, W., Parker, T., Upton, Z. & Lu, H., Oct 2013, In: Future Medicinal Chemistry. 5, 16, p. 1953-1965 13 p.Research output: Contribution to journal › Review article › peer-review
12 Citations (Scopus) -
2011
Advantages of Tandem LC−MS for the Rapid Assessment of Tissue-Specific Metabolic Complexity Using a Pentafluorophenylpropyl Stationary Phase
Lv, H., Palacios, G., Hartil, K. & Kurland, I. J., Apr 2011, In: Journal of Proteome Research. 10, 4, p. 2104-2112 9 p.Research output: Contribution to journal › Journal article › peer-review
31 Citations (Scopus) -
Development of an integrated metabolomic profiling approach for infectious diseases research
Lv, H., Hung, C. S., Chaturvedi, K. S., Hooton, T. M. & Henderson, J. P., 21 Nov 2011, In: Analyst. 136, 22, p. 4752-4763 12 p.Research output: Contribution to journal › Journal article › peer-review
40 Citations (Scopus) -
Metabolomic analysis characterizes tissue specific indomethacin-induced metabolic perturbations of rats
Lv, H., Liu, L., Palacios, G. & Chen, X., Jun 2011, In: Analyst. 136, 11, p. 2260-2269 10 p.Research output: Contribution to journal › Journal article › peer-review
7 Citations (Scopus) -
Yersinia high pathogenicity Island genes modify the Escherichia coli primary metabolome independently of siderophore production
Lv, H. & Henderson, J. P., Dec 2011, In: Journal of Proteome Research. 10, 12, p. 5547-5554 8 p.Research output: Contribution to journal › Journal article › peer-review
24 Citations (Scopus) -
2010
Pharmacokinetics-based elucidation on disparity in clinical effectiveness between varieties of Zhi Zhu Wan, a Traditional Chinese Medical formula
Cao, H., Chen, X., Sun, H., Sakurai, T., Zhou, J., Sun, W., Lv, H. & Wang, X., Apr 2010, In: Journal of Ethnopharmacology. 128, 3, p. 606-610 5 p.Research output: Contribution to journal › Journal article › peer-review
17 Citations (Scopus) -
Plasma metabolomics reveals biomarkers of the atherosclerosis
Chen, X., Liu, L., Palacios, G., Gao, J., Zhang, N., Li, G., Lu, J., Song, T., Zhang, Y. & Lv, H., Sept 2010, In: Journal of Separation Science. 33, 17-18, p. 2776-2783 8 p.Research output: Contribution to journal › Journal article › peer-review
78 Citations (Scopus) -
Thyroxine and reserpine-induced changes in metabolic profiles of rat urine and the therapeutic effect of Liu Wei Di Huang Wan detected by UPLC-HDMS
Wang, P., Sun, H., Lv, H., Sun, W., Yuan, Y., Han, Y., Wang, D., Zhang, A. & Wang, X., Nov 2010, In: Journal of Pharmaceutical and Biomedical Analysis. 53, 3, p. 631-645 15 p.Research output: Contribution to journal › Journal article › peer-review
86 Citations (Scopus) -
2008
Pharmacokinetic studies of a Chinese triple herbal drug formula
Lv, H., Sun, H., Sun, W., Liu, L., Wang, P., Wang, X. & Cao, H., Nov 2008, In: Phytomedicine. 15, 11, p. 993 - 1001 9 p.Research output: Contribution to journal › Journal article › peer-review
34 Citations (Scopus)