Projects per year
Personal profile
Chinese Name
Biography
Dr. Li Fangfei graduated from Ocean University of China with a bachelor's degree in Chemistry in 2007. Following two years of master education in Ocean University, she started her PhD study in Australia under China Scholarship Council (CSC) scholarship in 2009. Dr. Li obtained her PhD degree in Chemistry from University of New South Wales in Australia in 2013. After postdoctoral training at Institute of Microbiology, Chinese Academy of Science in Beijing, she joined school of Chinese Medicine at Hong Kong Baptist University as a postdoctoral fellow in 2015, and then served as a research assistant professor since 2016. In 2021, Dr. Li was appointed as a tenure-track assistant professor.
簡歷
李芳菲教授2007年本科畢業於中國海洋大學化學系,同年保送本校碩士研究生。2009年獲得國家留學基金委(CSC)資助赴澳大利亞新南威爾斯大學攻讀博士學位,2013年取得化學博士學位。回國後在中國科學院北京微生物所進行博士後研究。2015年加入香港浸會大學中醫藥學院進行博士後研究,2016年任職研究助理教授,2021年晉升為助理教授。
李教授的研究致力於腫瘤微環境細胞互作機製及基於新型藥物靶點的創新藥物研發,主要包括以下三個方向:1)胰腺導管癌腫瘤神經侵襲中的腫瘤-神經交互機製;2)腫瘤微環境中炎癥誘導的動態變化;3)來源中藥小分子的新型抗腫瘤藥物研發。她的研究成果主要發表於Nature Communications, Biomaterials, Chemical Science 等國際高水平期刊。
Research Interests
novel anti-cancer therapies and targeted drug delivery.
Education/Academic qualification
PhD, UNSW Sydney
Award Date: 31 Dec 2013
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Collaborations and top research areas from the last five years
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體外培育牛黃的疾病治療基礎與創新應用研究
LYU, A. (PI), HAN, S. Q. B. (CoPI), Jia, W. (CoPI), LI, F. (CoPI), Liang, C. (CoPI), Liu, J. (CoPI) & XU, J. (CoPI)
5/09/25 → 4/09/30
Project: Research project
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Developing an online self-learning platform of Licensed Pharmacists of Traditional Chinese Medicine Qualification Examination for undergraduates of Pharmacy in Chinese Medicine
LI, F. (PI), XU, J. (CoI), ZHANG, H. (CoI), CHEN, H. (CoI), LI, C. (CoI) & SU, D. D. M. (CoI)
1/01/25 → 30/08/26
Project: Teaching project
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Targeted Degradation of Nuclear uPA to Inhibit Perineural Invasion in Pancreatic Cancer via PROTAC Strategy
LI, F. (PI)
1/01/27 → 31/12/29
Project: Research project
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Aptamer-Based Proteolysis Targeting Chimera to Degrade Intracellular Sclerostin for Triple-Negative Breast Cancer Therapy
ZHANG, G. (PI), Chen, Q. (CoI), LI, F. (CoI), Ma, Y. (CoI), Sun, M. (CoI), Yu, K. (CoI) & Zhang, B. (CoI)
1/09/26 → 31/08/28
Project: Research project
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Icariin Enhances the Enzymatic Activity of N-acetylgalactosaminidase to Augment Akkermansia Abundance in Gut Microbiota for Improved PD-1 Blockade Efficacy in Tumor Suppression
Qiao, S., Yang, L., Hao, H., Ding, Q., Ding, F., Chen, Z., Zhang, J., He, Y., Li, M., Xu, J., Wang, C., Lu, A. & Li, F., 22 Apr 2026, (E-pub ahead of print) In: Advanced Science. 24 p., e19942.Research output: Contribution to journal › Journal article › peer-review
Open Access -
Intracellular sclerostin promotes tumor progression and metastasis as a potential therapeutic target in triple-negative breast cancer
Sun, M., Luo, H., Qiao, S., Chen, Z., Jiang, H., Yang, X., Ding, S., Tian, Y., Wu, Y., Wu, P., Zhang, Y., Tao, X., Yu, Y., Wang, L., Tian, J., Kang, W., Ma, D., He, Y., Lu, A. & Yuan, F.-L. & 5 others, , 19 May 2026, In: Cell Reports Medicine. 7, 5, 25 p., 102763.Research output: Contribution to journal › Journal article › peer-review
Open Access -
Schwann like reprogramming of cancer associated fibroblasts remodels the tumor neural niche in pancreatic ductal adenocarcinoma
Yang, L., Cui, X., Qiao, S., He, Y., Su, Z., Chen, Z., Ding, F., Lu, A. & Li, F., 1 Apr 2026, In: Cancer Research. 86, 7 Supplement, p. 6231-6231 1 p.Research output: Contribution to journal › Conference article › peer-review
Open Access -
Tumor nuclear uPA: A transcriptional modulator of perineural invasion in PDAC
He, Y., Su, Z., Ding, F., Chen, Z., Cui, X., Yang, L., Qiao, S., Hou, Y., Lu, A. & Li, F., 1 Apr 2026, In: Cancer Research. 86, 7 Supplement, p. 6230-6230 1 p.Research output: Contribution to journal › Conference article › peer-review
Open Access -
Abstract A021: Cancer-associated fibroblast-derived CXCL12 as a potential therapeutic target for pancreatic ductal adenocarcinoma immunotherapy
Yang, L., Lu, A. & Li, F., 1 Mar 2025, In: Cancer Research. 85, 5, Supplement, 1 p., A021.Research output: Contribution to journal › Conference article › peer-review
Prizes
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The 8th Hong Kong University Student Innovation and Entrepreneurship Competition
LI, F. (Recipient), 2022
Prize: Award
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Activities
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Experimental Cell Research (Journal)
LI, F. (Reviewer)
18 Jun 2024Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)
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Heliyon (Journal)
LI, F. (Reviewer)
16 Apr 2024Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)
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External Reviewer of University of Macau Multi-year Research Grant ( General Research Grant )
LI, F. (Advisor)
16 Apr 2024 → 20 Apr 2024Activity: Consultancy
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International Journal of Molecular Sciences (Journal)
LI, F. (Reviewer)
19 Apr 2024Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)
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Frontiers in Immunology (Journal)
LI, F. (Associate editor)
2024 → …Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)