Projects per year
Personal profile
Chinese Name
張璐
Biography
Dr. Lu (Eric) Zhang is an Associate Professor of Computer Science at Hong Kong Baptist University (HKBU). Before joining HKBU, he was a postdoctoral fellow in the Department of Computer Science and Pathology at Stanford University, supervised by Prof. Serafim Batzoglou and Prof. Arend Sidow. He received an MPhil degree from Li Ka Shing Faculty of Medicine at The University of Hong Kong and a Ph.D. degree in Computer Science from City University of Hong Kong in 2012 and 2016, respectively. In 2008, he received a B.Eng in Software Engineering from Tianjin University. In 2015, he was a visiting scholar in the Department of Mathematics at UC Berkeley and worked with Prof. Stephen Smale. He has an interdisciplinary background in genomics, statistics and computer science. His primary research interests are computational genomics, bioinformatics and AI for Genomics. His team works specifically on 1. Develop computational tools to support advanced high-throughput sequencing technologies on human gut metagenome. 2. Develop foundation models on metagenomics and single-cell multiomics data. 3. Explore the application of Large Language Models on modern healthcare problems. His work has been published in several top-tier journals, such as PNAS, Briefings in Nature Machine Intellgence, Bioinformatics, NAR Genomics and Bioinformatics, GigaScience, Nature Communications, Nature Genetics, Genome Biology, Bioinformatics, etc
Research Interests
His primary research interests are computational genomics, bioinformatics, AI for genomics and machine learning.
Education/Academic qualification
Postdoctoral Fellow, Stanford University
18 Jun 2016 → 31 Jan 2019
Award Date: 31 Jan 2019
PhD student, City University of Hong Kong
1 Sept 2012 → 15 Feb 2016
Award Date: 15 Feb 2016
Mphil Student, The University of Hong Kong
1 Sept 2010 → 31 Aug 2012
Award Date: 31 Aug 2012
Undergraduate student, Tianjin University
1 Sept 2004 → 15 Jul 2008
Award Date: 15 Jul 2008
Keywords
- QA75 Electronic computers. Computer science
- Bioinformatics
- Computational Genomics
- AI for Science
Fingerprint
Dive into the research topics where Lu ZHANG is active. Topic labels come from the works of this scholar.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Towards Trustworthy Foundation Models under Imperfect Scenarios
HAN, B. (PI), ZHANG, L. (CoPI), CHEUNG, Y. M. (CoPI), Cheng, J. (CoPI) & Zhu, L. (CoPI)
1/06/25 → 31/05/28
Project: Research project
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Advancing clinical differentiation between constipation-predominant irritable bowel syndrome and functional constipation using machine learning models
ZHANG, L. (PI), VELDSMAN, W. P. (CoI), BIAN, Z. (CoI) & Lam, Y. Y. (CoI)
14/09/24 → 13/09/27
Project: Research project
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Improved Metabolic Network Reconstruction and Metabolite Profiles Prediction using Complete and Strain-Resolved Microbial Genomes
ZHANG, L. (PI), BIAN, Z. (CoPI), ZHAI, L. (CoPI), Li, S. (CoPI) & Li, J. (CoPI)
30/06/24 → 31/05/27
Project: Research project
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AI Models Helping Combat Antibiotic Resistance in ICU – Personalized Decision Support for Empirical Antibiotic Therapy
YIN, K. (PI), CHEUNG, K. W. (CoI), ZHANG, L. (CoI), Tong, T. M. C. (CoI) & SIN, C. T. E. (CoI)
1/04/24 → 31/03/27
Project: Research project
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Investigation of abdominal pain management in diarrhea-predominant irritable bowel syndrome via short-chain fatty acids/GLP-1 axis
BIAN, Z. (PI), ZHANG, L. (CoI) & WONG, H. L. X. (CoI)
1/01/24 → 31/12/26
Project: Research project
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AI-Empowered Evidence-Based Research and Clinical Decision-Making
Luo, X., Ge, L., Zhang, L., Chen, Y., Du, L. & ADVANCED Working Group, Mar 2025, In: Journal of Evidence-Based Medicine. 18, 1, e70014.Research output: Contribution to journal › Editorial
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A multimodal framework for early detection and classification of social isolation and loneliness among Chinese older adults
Song, H., Lyu, J., Zhang, L. & Cheung, C. M. K., Dec 2025, In: Briefings in Bioinformatics. 26, Supplement 1, p. i20 1 p.Research output: Contribution to journal › Conference article › peer-review
Open Access -
Causal Transformer for Learning Embeddings from Structured Medical History Records and Multi-Source Data Integration for Complex Disease Risk Prediction
Li, Z., Xu, Y., Chowdhury, D., Yip, H. F., Wang, C. & Zhang, L., 17 Sept 2025, (E-pub ahead of print) In: Interdisciplinary Sciences - Computational Life Sciences. 14 p.Research output: Contribution to journal › Journal article › peer-review
Open Access -
Cross-tissue multi-omics analyses reveal the gut microbiota's absence impacts organ morphology, immune homeostasis, bile acid and lipid metabolism
Shen, J., Liang, W., Zhao, R., Chen, Y., Liu, Y., Cheng, W., Chai, T., Zhang, Y., Chen, S., Liu, J., Chen, X., Deng, Y., Zhang, Z., Huang, Y., Yang, H., Pang, L., Qiu, Q., Deng, H., Pan, S. & Wang, L. & 16 others, , Feb 2025, In: iMeta. 4, 1, 27 p., e272.Research output: Contribution to journal › Journal article › peer-review
Open Access8 Citations (Scopus) -
DBNX: A Machine Learning Method for Ensembling Polygenic Risk Scores and Non-Genetic Factors
Yuan, X., Wang, C., Zhu, S. & Zhang, L., Sept 2025, In: IEEE Transactions on Computational Biology and Bioinformatics. 22, 5, p. 2031-2042 12 p.Research output: Contribution to journal › Journal article › peer-review
Open Access
Prizes
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President’s Award for Outstanding Performance as Early Career Researcher
ZHANG, L. (Recipient), 2023
Prize: Award
Activities
- 8 Editor/reviewer for publications (incl. CDCF T61 Journal Editor)
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BMC Methods (Journal)
ZHANG, L. (Member of editorial board)
2023 → …Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)
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Health Information Science and Systems (Journal)
ZHANG, L. (Guest editor)
Apr 2023Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)
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Frontiers in Genetics (Journal)
ZHANG, L. (Guest editor)
2022Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)
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Life (Journal)
ZHANG, L. (Guest editor)
2022Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)
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Current Gene Therapy (Journal)
ZHANG, L. (Member of editorial board)
14 Nov 2022 → 30 Jun 2023Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)