Projects per year
Personal profile
Chinese Name
Biography
Professor Bian Zhaoxiang is a leading expert in Chinese Medicine clinical studies, a respected research scientist in the field of gut dysbiosis, and a relentless advocate for incorporating Chinese Medicine into a holistic healthcare system. Currently, Professor Bian Zhaoxiang holds these positions in the School of Chinese Medicine at HKBU: Associate Vice-President for Chinese Medicine Development; Director and Chair Professor of the Clinical Division; Director, Centre for Chinese Herbal Medicine Drug Development; Director, Chinese EQUATOR Centre; and Director, Hong Kong Chinese Medicine Clinical Study Centre. He also serves as an associate editor and editorial board member for many international peer review journals, including Trials, BMC-Complementary and Alternative Medicine, and Chinese Medicine.
Professor Bian’s academic training includes: BS (Chinese Medicine) and MPhil (Chinese Medicine), from both Nanjing University of Traditional Chinese Medicine and Beijing University of Traditional Chinese Medicine, PhD (Integrative Medicine), Guangzhou University of Traditional Chinese Medicine. Professor Bian joined HKBU in 2001. His research focuses on digestive diseases, especially colorectal cancer, irritable bowel syndrome (IBS)functional constipation (FC) and inflammatory bowel disease (IBD), and on related new drug discovery.
Another thrust of his professional interests is the design, implementation and reporting of clinical trials with Chinese Medicine. Realizing the imperative need for conducting rigorous, accurate Chinese Medicine clinical studies, Professor Bian initiated the establishment, and later became Director, of the Hong Kong Chinese Medicine Clinical Study Centre, the first and only centre focusing on Chinese Medicine clinical trials in Hong Kong. Prof. Bian has been instrumental in developing reporting guidelines for various aspects of Chinese Medicine, from protocol development, trial registration, and outcome reporting to systematic review. Further, Prof Bian has established the Chinese EQUATOR Centre, a center devoted to enhancing the quality and transparency of health research in general and of clinical research in Chinese Medicine in particular.
Prof Bian has been, and is a long-time advocate for the establishment of a Chinese Medicine Hospital (CMH) in Hong Kong. In June 2021, Hong Kong Baptist University was selected by the HKSAR Government as the contractor for the service deed of Hong Kong’s first CMH. Prof Bian will continue his efforts to make this historical project a big success.
As of August 2021, Professor Bian has registered 72 patents, and presented and/or published over 500 papers in journals, books and conferences. In collaboration with researchers at the Chinese University of Hong Kong, he led a research team that developed a new herbal medicine for IBS. In 2014, the NMPA of China granted a clinical trial license for the drug; in 2016 the formula was licensed to a drug company. For his outstanding research, Prof Bian has received local, national and international awards including second prize in the National Science and Technology Advancement Award of China.
Research Interests
- Basic mechanism of visceral hyperalgesia and gastrointestinal motility disorder and its associated depression.
- The design, implementation and reporting of clinical trial with Chinese medicine for digestive diseases, especially colorectal cancer, irritable bowel syndrome (IBS), functional constipation (FC), and inflammatory bowel disease (IBD).
- New drug development based on Chinese herbal medicine and its active fraction for digestive diseases.
- Reporting guidelines for various aspects of Chinese Medicine, from protocol development, trial registration, and outcome reporting to systematic review.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Visiting Research Fellow, China Academy of Chinese Medical Science
Honorary Professor, Guangzhou University of Traditional Chinese Medicine
Honorary Professor, Shanghai University of Traditional Chinese Medicine
Honorary Professor, Tianjin University of Traditional Chinese Medicine
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Collaborations and top research areas from the last five years
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User-Controlled Secure Data Sharing and Analytics with Blockchain and Trusted Computing Technologies
XU, J., Cao, J., Chen, L., CHU, X., Hu, H., Wang, C., BIAN, Z. & Zhang, K.
1/05/22 → 30/04/25
Project: Research project
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Investigating the regulatory role of phenethylamine for serotonin production in the pathogenesis of diarrhea-predominant Irritable Bowel Syndrome
1/01/22 → 31/12/24
Project: Research project
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Gut dysbiosis disrupts stem cell functions via NGF/TrkA signaling pathway in diarrhea-predominant irritable bowel syndrome
1/01/21 → 31/12/23
Project: Research project
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Investigation of abdominal pain management in diarrhea-predominant irritable bowel syndrome via short-chain fatty acids/GLP-1 axis
BIAN, Z., ZHANG, L. & WONG, H. L. X.
1/01/24 → 31/12/26
Project: Research project
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A cross-sectional study of the endorsement proportion of reporting guidelines in 1039 Chinese medical journals
Duan, Y., Zhao, L., Ma, Y., Luo, J., Chen, J., Miao, J., Zhang, X., Moher, D. & Bian, Z., 21 Jan 2023, In: BMC Medical Research Methodology. 23, 10 p., 20.Research output: Contribution to journal › Journal article › peer-review
Open Access1 Citation (Scopus) -
Acupuncture for olfactory dysfunction in infected COVID-19 patients: Study protocol for a randomized, sham-controlled clinical trial
Zhong, L. L., Wong, Y., Leung, C., Choy, C., Cho, H., Wong, A. Y., Yau, K., Wong, R. H., Ng, B. F. & Bian, Z., Jan 2023, In: Journal of Traditional Chinese Medical Sciences. 10, 1, p. 118-124 7 p.Research output: Contribution to journal › Journal article › peer-review
Open Access -
Altered gut microbiota–host bile acid metabolism in IBS-D patients with liver depression and spleen deficiency pattern
Du, L., Zhang, Z., Zhai, L., Xu, S., Yang, W., Huang, C., Lin, C., Zhong, L. L. D., Bian, Z. & Zhao, L., 19 Jul 2023, In: Chinese Medicine (United Kingdom). 18, 13 p., 87.Research output: Contribution to journal › Journal article › peer-review
Open Access -
Aqueous cinnamon extract ameliorates bowel dysfunction and enteric 5-HT synthesis in IBS rats
Yu, L., Huang, C., Yang, W., Ren, Z., Li, L., Cheng, H., Lin, C., Zhai, L., Ning, Z., Wong, H. X., Han, Q., Jia, W., Bian, Z. & Zhao, L., 9 Jan 2023, In: Frontiers in Pharmacology. 13, 11 p., 1010484.Research output: Contribution to journal › Journal article › peer-review
Open Access1 Citation (Scopus) -
Detecting the skewness of data from the five-number summary and its application in meta-analysis
Shi, J., Luo, D., Wan, X., Liu, Y., Liu, J., Bian, Z. & Tong, T., Jul 2023, In: Statistical Methods in Medical Research. 32, 7, p. 1338-1360 23 p.Research output: Contribution to journal › Journal article › peer-review
5 Citations (Scopus)
Prizes
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4th internal conference of integrated digestive disease
BIAN, Zhaoxiang (Recipient), 2013
Prize: Award
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International Award for Contribution to Chinese Medicine -achievement Award in Medical Science
BIAN, Zhaoxiang (Recipient), 2018
Prize: Award
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Activities
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GI research with Chinese herbal medicine, from clinical research to new drug discovery
Zhaoxiang BIAN (Speaker)
11 Aug 2022 → 12 Aug 2022Activity: Conference/talk/lecture/symposium/speech/workshop, etc › Event organized by non-HKBU units
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Application of Intelligent Research Methods in TCM Auxiliary Diagnosis and Treatment
Zhaoxiang BIAN (Plenary/keynote speaker)
24 Sept 2020 → 25 Sept 2020Activity: Conference/talk/lecture/symposium/speech/workshop, etc › Event organized by non-HKBU units
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Clostridium-enriched enterotype contribute to bile acid over-synthesis in patients with diarrhea-predominant irritable bowel syndrome
Zhaoxiang BIAN (Plenary/keynote speaker)
19 Aug 2019Activity: Conference/talk/lecture/symposium/speech/workshop, etc › Event organized by non-HKBU units
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Digital Chinese Medicine (Journal)
Zhaoxiang BIAN (Member of editorial board)
2018Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)
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Traditional Chinese and Western Medicine, What can we learn from each other?
Zhaoxiang BIAN (Speaker)
20 Jun 2017 → 21 Jun 2017Activity: Conference/talk/lecture/symposium/speech/workshop, etc › Event organized by non-HKBU units
Press/Media
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Press conference on the new regulatory mechanism of satiety and therapeutic target for obesity research
Hoi Leong Xavier WONG & Zhaoxiang BIAN
30/05/22 → 31/05/22
5 items of Media coverage, 1 Media contribution
Press/Media