Research output per year
Research output per year
- 1 - 50 out of 93 results
Search results
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2024
Connective Tissue Growth Factor: Regulation, Diseases, and Drug Discovery
Ren, M., Yao, S., Chen, T., Luo, H., Tao, X., Jiang, H., Yang, X., Zhang, H., Yu, S., Wang, Y., Lu, A. & Zhang, G., 1 May 2024, In: International Journal of Molecular Sciences. 25, 9, 23 p., 4692.Research output: Contribution to journal › Review article › peer-review
Open Access -
Inflammatory Processes: Key Mediators of Oncogenesis and Progression in Pancreatic Ductal Adenocarcinoma (PDAC)
Yang, L., Qiao, S., Zhang, G., Lu, A. & Li, F., 12 Oct 2024, In: International Journal of Molecular Sciences. 25, 20, 16 p., 10991.Research output: Contribution to journal › Review article › peer-review
Open Access -
2023
Apolipoproteins as potential communicators play an essential role in the pathogenesis and treatment of early atherosclerosis
Li, Y., Luo, X., Hua, Z., Xue, X., Wang, X., Pang, M., Wang, T., Lyu, A. & Liu, Y., 21 Aug 2023, In: International Journal of Biological Sciences. 19, 14, p. 4493-4510 18 p.Research output: Contribution to journal › Review article › peer-review
Open Access8 Citations (Scopus) -
Exosomes-mediated tumor metastasis through reshaping tumor microenvironment and distant niche
Luo, X., Li, Y., Hua, Z., Xue, X., Wang, X., Pang, M., Xiao, C., Zhao, H., Lyu, A. & Liu, Y., Jan 2023, In: Journal of Controlled Release. 353, p. 327-336 10 p.Research output: Contribution to journal › Review article › peer-review
31 Citations (Scopus) -
Inappropriate treatment response to DMARDs: A pathway to difficult-to-treat rheumatoid arthritis
Guo, H., Li, L., Liu, B., Lu, P., Cao, Z., Ji, X., Li, L., Ouyang, G., Nie, Z., Lyu, A. & Lu, C., Sept 2023, In: International Immunopharmacology. 122, 110655.Research output: Contribution to journal › Review article › peer-review
Open Access6 Citations (Scopus) -
Lipid metabolism and rheumatoid arthritis
Lei, Q., Yang, J., Li, L., Zhao, N., Lu, C., Lu, A. & He, X., 31 May 2023, In: Frontiers in Immunology. 14, 14 p., 1190607.Research output: Contribution to journal › Review article › peer-review
Open Access22 Citations (Scopus) -
Natural Compounds Targeting the Autophagy Pathway in the Treatment of Colorectal Cancer
Du, Y-X., Mamun, A. A., Lyu, A-P. & Zhang, H-J., Apr 2023, In: International Journal of Molecular Sciences. 24, 8, 28 p., 7310.Research output: Contribution to journal › Review article › peer-review
Open Access10 Citations (Scopus) -
Organoids as Innovative Models for Bone and Joint Diseases
Huang, J., Zhang, L., Lu, A. & Liang, C., 2 Jun 2023, In: Cells. 12, 12, 22 p., 1590.Research output: Contribution to journal › Review article › peer-review
Open Access11 Citations (Scopus) -
Targeted protein degradation in cancers: Orthodox PROTACs and beyond
Li, J., Chen, X., Lu, A. & Liang, C., 15 May 2023, In: The Innovation. 4, 3, 15 p., 100413.Research output: Contribution to journal › Review article › peer-review
Open Access24 Citations (Scopus) -
The molecular insights of bile acid homeostasis in host diseases
Zhang, J., Lyu, A. & Wang, C., 1 Oct 2023, In: Life Sciences. 330, 121919.Research output: Contribution to journal › Review article › peer-review
2 Citations (Scopus) -
The roles of hepatokine and osteokine in liver-bone crosstalk: Advance in basic and clinical aspects
LI, Z., Wen, X., LI, N., ZHONG, C., Chen, L., Zhang, F., Zhang, G., Lu, A. & LIU, J., 6 Apr 2023, In: Frontiers in Endocrinology. 14, 1149233.Research output: Contribution to journal › Review article › peer-review
Open Access4 Citations (Scopus) -
2022
CRISPR/Cas systems: Delivery and application in gene therapy
Huang, J., Zhou, Y., Li, J., Lu, A. & Liang, C., 22 Nov 2022, In: Frontiers in Bioengineering and Biotechnology. 10, 21 p., 942325.Research output: Contribution to journal › Review article › peer-review
Open Access34 Citations (Scopus) -
Drug discovery of sclerostin inhibitors
Yu, S., Li, D., Zhang, N., Ni, S., Sun, M., Wang, L., Xiao, H., Liu, D., Liu, J., Yu, Y., Zhang, Z., Yeung, S. T. Y., Zhang, S., Lu, A., Zhang, Z., Zhang, B. & Zhang, G., May 2022, In: Acta Pharmaceutica Sinica B. 12, 5, p. 2150-2170 21 p.Research output: Contribution to journal › Review article › peer-review
Open Access25 Citations (Scopus) -
Featurization strategies for protein–ligand interactions and their applications in scoring function development
Xiong, G., Shen, C., Yang, Z., Jiang, D., Liu, S., Lu, A., Chen, X., Hou, T. & Cao, D., Mar 2022, In: Wiley Interdisciplinary Reviews: Computational Molecular Science. 12, 2, e1567.Research output: Contribution to journal › Review article › peer-review
35 Citations (Scopus) -
Natural products for infectious microbes and diseases: an overview of sources, compounds, and chemical diversities
Luo, L., Yang, J., Wang, C., Wu, J., Li, Y., Zhang, X., Li, H., Zhang, H., Zhou, Y., Lu, A. & Chen, S., Jun 2022, In: Science China Life Sciences. 65, 6, p. 1123–1145 23 p.Research output: Contribution to journal › Review article › peer-review
Open Access23 Citations (Scopus) -
Pu-erh tea: A review of a healthful brew
Jia, W., Rajani, C., Lv, A., Fan, T. P. & Zheng, X., Apr 2022, In: Journal of Traditional Chinese Medical Sciences. 9, 2, p. 95-99 5 p.Research output: Contribution to journal › Review article › peer-review
Open Access9 Citations (Scopus) -
Strategies for developing long-lasting therapeutic nucleic acid aptamer targeting circulating protein: The present and the future
Zhang, Y., Zhang, H., Chan, D. W. H., Ma, Y., Lu, A., Yu, S., Zhang, B. & Zhang, G., 1 Nov 2022, In: Frontiers in Cell and Developmental Biology. 10, 11 p., 1048148.Research output: Contribution to journal › Review article › peer-review
Open Access11 Citations (Scopus) -
The effect of long non-coding RNAs in joint destruction of rheumatoid arthritis
Zhao, H., Li, L., Zhao, N., Lu, A., Lu, C. & He, X., 3 Oct 2022, In: Frontiers in Cell and Developmental Biology. 10, 10 p., 1011371.Research output: Contribution to journal › Review article › peer-review
Open Access2 Citations (Scopus) -
The endoplasmic reticulum participated in drug metabolic toxicity
Huang, Q., Chen, Y., Zhang, Z., Xue, Z., Hua, Z., Luo, X., Li, Y., Lu, C., Lu, A. & Liu, Y., Dec 2022, In: Cell Biology and Toxicology. 38, 6, p. 945-961 17 p.Research output: Contribution to journal › Review article › peer-review
6 Citations (Scopus) -
2021
A review of computational tools for generating metagenome-assembled genomes from metagenomic sequencing data
YANG, C., CHOWDHURY, D., ZHANG, Z., CHEUNG, W. K. W., LYU, A., BIAN, Z. & ZHANG, L., 29 Nov 2021, In: Computational and Structural Biotechnology Journal. 19, p. 6301-6314 14 p.Research output: Contribution to journal › Review article › peer-review
Open Access102 Citations (Scopus) -
Artificial Intelligence in Aptamer–Target Binding Prediction
Chen, Z., Hu, L., Zhang, B-T., Lu, A., Wang, Y., Yu, Y. & Zhang, G., 1 Apr 2021, In: International Journal of Molecular Sciences. 22, 7, 3605.Research output: Contribution to journal › Review article › peer-review
Open Access59 Citations (Scopus) -
Cis-Regulatory Logic Produces Gene-Expression Noise Describing Phenotypic Heterogeneity in Bacteria
Chowdhury, D., Wang, C., Lu, A. & Zhu, H., 28 Sept 2021, In: Frontiers in Genetics. 12, 698910.Research output: Contribution to journal › Review article › peer-review
Open Access2 Citations (Scopus) -
Current advances in ligand-based target prediction
Yang, S. Q., Ye, Q., Ding, J. J., Ming-Zhu, Y., Lyu, A., Chen, X., Hou, T. J. & Cao, D. S., 1 May 2021, In: Wiley Interdisciplinary Reviews: Computational Molecular Science. 11, 3, e1504.Research output: Contribution to journal › Review article › peer-review
23 Citations (Scopus) -
Dickkopf-1: A Promising Target for Cancer Immunotherapy
Chu, H. Y., Chen, Z., Wang, L., Zhang, Z. K., Tan, X., Liu, S., Zhang, B. T., Lu, A., Yu, Y. & Zhang, G., 20 May 2021, In: Frontiers in Immunology. 12, 14 p., 658097.Research output: Contribution to journal › Review article › peer-review
Open Access46 Citations (Scopus) -
How Perturbated Metabolites in Diabetes Mellitus Affect the Pathogenesis of Hypertension?
Ning, Z., Song, Z., Wang, C., Peng, S., Wan, X., Liu, Z. & Lu, A., 18 Aug 2021, In: Frontiers in Physiology. 12, 705588.Research output: Contribution to journal › Review article › peer-review
Open Access4 Citations (Scopus) -
Nab-paclitaxel promotes the cancer-immunity cycle as a potential immunomodulator
Chen, Y., Liu, R., Li, C., Song, Y., Liu, G., Huang, Q., Yu, L., Zhu, D., Lu, C., Lu, A., Li, L. & Liu, Y., 30 Jul 2021, In: American Journal of Cancer Research. 11, 7, p. 3445-3460 16 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
Natural products in drug discovery: advances and opportunities
Atanasov, A. G., Zotchev, S. B., Dirsch, V. M., Orhan, I. E., Banach, M., Rollinger, J. M., Barreca, D., Weckwerth, W., Bauer, R., Bayer, E. A., Majeed, M., Bishayee, A., Bochkov, V., Bonn, G. K., Braidy, N., Bucar, F., Cifuentes, A., D’Onofrio, G., Bodkin, M., Diederich, M., & 54 others, Mar 2021, In: Nature Reviews Drug Discovery. 20, 3, p. 200-216 17 p.Research output: Contribution to journal › Review article › peer-review
Open Access2621 Citations (Scopus) -
Structural Biology for the Molecular Insight between Aptamers and Target Proteins
Zhang, N., Chen, Z., Liu, D., Jiang, H., Zhang, Z-K., Lu, A., Zhang, B-T., Yu, Y. & Zhang, G., 15 Apr 2021, In: International Journal of Molecular Sciences. 22, 8, 27 p., 4093.Research output: Contribution to journal › Review article › peer-review
Open Access42 Citations (Scopus) -
Targeting Strategies for Enhancing Paclitaxel Specificity in Chemotherapy
Ma, Y., Yu, S., Ni, S., Zhang, B., Kung, A. C. F., Gao, J., Lu, A. & Zhang, G., 29 Mar 2021, In: Frontiers in Cell and Developmental Biology. 9, 17 p., 626910.Research output: Contribution to journal › Review article › peer-review
Open Access27 Citations (Scopus) -
The Application of Microfluidic Technologies in Aptamer Selection
Liu, Y., Wang, N., Chan, C-W., Lu, A., Yu, Y., Zhang, G. & Ren, K., 17 Sept 2021, In: Frontiers in Cell and Developmental Biology. 9, 11 p., 730035.Research output: Contribution to journal › Review article › peer-review
Open Access27 Citations (Scopus) -
Triptolide delivery: Nanotechnology-based carrier systems to enhance efficacy and limit toxicity
Ren, Q., Li, M., Deng, Y., Lu, A. & Lu, J., Mar 2021, In: Pharmacological Research. 165, 105377.Research output: Contribution to journal › Review article › peer-review
40 Citations (Scopus) -
2020
Advances in the discovery of exosome inhibitors in cancer
Zhang, H., Lu, J., Liu, J., Zhang, G. & Lu, A., 16 Jun 2020, In: Journal of Enzyme Inhibition and Medicinal Chemistry. 35, 1, p. 1322-1330 9 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile83 Citations (Scopus)41 Downloads (Pure) -
Application of negative design to design a more desirable virtual screening library
Yang, Z. Y., He, J. H., Lu, A. P., Hou, T. J. & Cao, D. S., 14 May 2020, In: Journal of Medicinal Chemistry. 63, 9, p. 4411-4429 19 p.Research output: Contribution to journal › Review article › peer-review
23 Citations (Scopus) -
Cathepsin K: The Action in and Beyond Bone
Dai, R., Wu, Z., Chu, H. Y., Lu, J., Lyu, A., Liu, J. & Zhang, G., 4 Jun 2020, In: Frontiers in Cell and Developmental Biology. 8, 13 p., 433.Research output: Contribution to journal › Review article › peer-review
Open AccessFile116 Citations (Scopus)73 Downloads (Pure) -
Frequent hitters: nuisance artifacts in high-throughput screening
Yang, Z. Y., He, J. H., Lu, A. P., Hou, T. J. & Cao, D. S., Apr 2020, In: Drug Discovery Today. 25, 4, p. 657-667 11 p.Research output: Contribution to journal › Review article › peer-review
40 Citations (Scopus) -
Natural ingredient-based polymeric nanoparticles for cancer treatment
Wong, K. H., Lu, A., Chen, X. & Yang, Z., 2 Aug 2020, In: Molecules. 25, 16, 3620.Research output: Contribution to journal › Review article › peer-review
Open Access76 Citations (Scopus) -
Potential Advantages of Bioactive Compounds Extracted From Traditional Chinese Medicine to Inhibit Bone Destructions in Rheumatoid Arthritis
Shi, Y., Shu, H., Wang, X., Zhao, H., Lu, C., Lu, A. & He, X., 7 Oct 2020, In: Frontiers in Pharmacology. 11, 16 p., 561962.Research output: Contribution to journal › Review article › peer-review
Open Access23 Citations (Scopus) -
Progress in 11β-HSD1 inhibitors for the treatment of metabolic diseases: A comprehensive guide to their chemical structure diversity in drug development
Chuanxin, Z., Shengzheng, W., Lei, D., Duoli, X., Jin, L., Fuzeng, R., Lu, A. & Zhang, G., 1 Apr 2020, In: European Journal of Medicinal Chemistry. 191, 20 p., 112134.Research output: Contribution to journal › Review article › peer-review
Open AccessFile19 Citations (Scopus)100 Downloads (Pure) -
Roles of MicroRNAs in Bone Destruction of Rheumatoid Arthritis
Zhao, H., Lu, A. & He, X., 19 Nov 2020, In: Frontiers in Cell and Developmental Biology. 8, 9 p., 600867.Research output: Contribution to journal › Review article › peer-review
Open Access20 Citations (Scopus) -
The ups and downs of Poly(ADP-ribose) Polymerase-1 inhibitors in cancer therapy–Current progress and future direction
Zhao, Y., Zhang, L. X., Jiang, T., Long, J., Ma, Z. Y., Lu, A. P., Cheng, Y. & Cao, D. S., 1 Oct 2020, In: European Journal of Medicinal Chemistry. 203, 112570.Research output: Contribution to journal › Review article › peer-review
48 Citations (Scopus) -
2019
microRNA-Mediated Regulation of Bone Remodeling: A Brief Review
Liu, J., Dang, L., Wu, X., Li, D., Ren, Q., Lu, A. & Zhang, G., Sept 2019, In: JBMR Plus. 3, 9, 9 p., e10213.Research output: Contribution to journal › Review article › peer-review
Open Access27 Citations (Scopus) -
Review of Current Strategies for Delivering Alzheimer’s Disease Drugs across the Blood-Brain Barrier
Wong, K. H., Riaz, M. K., Xie, Y., Zhang, X., Liu, Q., Chen, H., Bian, Z., Chen, X., Lu, A. & Yang, Z., 17 Jan 2019, In: International Journal of Molecular Sciences. 20, 2, 26 p., 381.Research output: Contribution to journal › Review article › peer-review
Open Access154 Citations (Scopus) -
Targeting Approaches of Nanomedicines in Acute Myeloid Leukemia
Huang, X., Lin, H., Huang, F., Xie, Y., Wong, K. H., Chen, X., Wu, D., Lu, A. & Yang, Z., 1 Oct 2019, In: Dose-Response. 17, 4, p. 1-14 14 p.Research output: Contribution to journal › Review article › peer-review
Open Access19 Citations (Scopus) -
Understanding quantitative circadian regulations are crucial towards advancing chronotherapy
Chowdhury, D., Wang, C., Lu, A. P. & Zhu, H. L., Aug 2019, In: Cells. 8, 8, 883.Research output: Contribution to journal › Review article › peer-review
Open Access14 Citations (Scopus) -
雷公藤甲素毒性作用及减毒研究的整合探析
Translated title of the contribution :Side Effect and Attenuation of Triptolide Research output: Contribution to journal › Review article › peer-review
4 Citations (Scopus) -
2018
Advances in the discovery of cathepsin K inhibitors on bone resorption
Lu, J., Wang, M., Wang, Z., Fu, Z., LYU, A. & ZHANG, G., 1 Jan 2018, In: Journal of Enzyme Inhibition and Medicinal Chemistry. 33, 1, p. 890-904 15 p.Research output: Contribution to journal › Review article › peer-review
Open Access56 Citations (Scopus) -
Appraisal of the Quality and Contents of Clinical Practice Guidelines for Hypertension Management in Chinese Medicine: A Systematic Review
Yuwen, Y., Han, X. J., Weng, W. L., Zhao, X. Y., Liu, Y. Q., Li, W. Q., Liu, D. S., Wang, Y. P. & Lyu, A., 1 Jul 2018, In: Chinese Journal of Integrative Medicine. 24, 7, p. 545-550 6 p.Research output: Contribution to journal › Review article › peer-review
6 Citations (Scopus) -
Surface functionalization and targeting strategies of liposomes in solid tumor therapy: A review
Riaz, M. K., Riaz, M. A., Zhang, X., Lin, C., Wong, K. H., Chen, X., Zhang, G., Lu, A. & Yang, Z., 9 Jan 2018, In: International Journal of Molecular Sciences. 19, 1, 27 p., 195.Research output: Contribution to journal › Review article › peer-review
Open Access377 Citations (Scopus) -
The effect of triptolide in rheumatoid arthritis: From basic research towards clinical translation
Fan, D., Guo, Q., Shen, J., Zheng, K., Lu, C., Zhang, G., Lu, A. & He, X., Feb 2018, In: International Journal of Molecular Sciences. 19, 2, 17 p., 376.Research output: Contribution to journal › Review article › peer-review
Open Access97 Citations (Scopus) -
2017
Aptamer-assembled nanomaterials for fluorescent sensing and imaging
Lu, D., He, L., ZHANG, G., LYU, A., Wang, R., Zhang, X. & Tan, W., 1 Jan 2017, In: Nanophotonics. 6, 1, p. 109-121 13 p.Research output: Contribution to journal › Review article › peer-review
Open Access45 Citations (Scopus)