School of Chinese Medicine

Research Output

Research output per year 1984 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025

• 3134 Journal article
• 402 Review article
• 211 Patent
• 99 Conference paper
• 413 More
  • 76 Book or report
  • 63 Conference proceeding
  • 63 Conference article
  • 62 Conference abstract
  • 57 Chapter
  • 47 Editorial
  • 20 Letter
  • 18 Conference poster
  • 7 Preprint

Research output per year

Research output per year

Search results

• 2024

  Discovery of a core inflammatory gene network associated with poor prognosis and characterized immune infiltration pattern in pancreatic ductal adenocarcinoma

  Yang, L., Chen, Z., Sheng, Y., Chowdhury, D., Yip, H. F., Qiao, S., Sun, M., Lu, A. & Li, F., 15 Jan 2024, In: Cancer Research. 84, 2 (Supplement), C042.

  Research output: Contribution to journal › Conference article › peer-review

• Inflammatory gene-based subtyping of osteosarcoma patients reveals the association of inflammation in tumor microenvironment with better survival

  Yang, L., Sheng, Y., Qiao, S., Hu, D., Chowdhury, D., Yip, H. F., Chen, Z., He, Y., Lu, A. & Li, F., 15 Mar 2024, In: Cancer Research. 84, 6 (Supplement), 5459.

  Research output: Contribution to journal › Conference article › peer-review

• Intracellular sclerostin plays a vital role in tumor progression and metastasis in triple-negative breast cancer

  Sun, M., Qiao, S., Luo, H., Yang, X., Yang, L., Zhang, H., Chen, Z., Wang, L., Tao, X., Yu, Y., Ma, Y., Yuan, F., Ma, D., Chen, Q., Lu, A., Zhang, B. T., Zhang, G. & Li, F., 1 Feb 2024, In: Cancer Research. 84, 3, Supplement 1, B044.

  Research output: Contribution to journal › Conference article › peer-review

  • Triple Negative Breast Neoplasms 100%
  • Neoplasm Metastasis 51%
  • Neoplasms 26%
  • Growth 17%
  • In Vitro Techniques 12%
• 2023

  A core inflammatory gene network associated with poor prognosis serves chemokine production in cancer associated fibroblasts in pancreatic ductal adenocarcinoma

  Li, F., Yang, L., Chen, Z., Qiao, S., Sheng, Y., Chowdhury, D., Yip, H. F., Sun, M. & Lu, A., 1 Dec 2023, In: Cancer Immunology Research. 11, 12, Supplement, B043.

  Research output: Contribution to journal › Conference article › peer-review

  • Cancer-Associated Fibroblasts 100%
  • Gene Regulatory Networks 77%
  • Chemokines 67%
  • Adenocarcinoma 56%
  • RNA-Seq 34%

• BCKDK, a novel hypoxia-responsive factor/kinase that exacerbates cerebral ischemia injury (Abstract)

  Liao, B., Geng, L., Jia, W. & Hoo, R. L. C., 10 Oct 2023, In: International Journal of Stroke. 18, 3, suppl., p. 345-346 2 p.

  Research output: Contribution to journal › Conference article

  Open Access

  • Branched Chain Amino Acids 100%
  • Brain Ischemia 76%
  • Hypoxia 60%
  • Phosphotransferases 59%
  • Wounds and Injuries 37%

• Establishment of isoliquiritigenin as a novel autophagy-ferritinophagy regulator in pancreatic cancer adjuvant chemotherapy (Abstract)

  Ko, J. & Zhang, Z., 8 Jun 2023, In: Molecular Oncology. 17, Supplement 1, p. 120-121 2 p.

  Research output: Contribution to journal › Conference article › peer-review

  Open Access

• How can herbal medicine be well developed under the current regulatory system? (Abstract)

  Bian, Z. X., Nov 2023, In: Planta Medica. 89, 14, p. 1377-1377 1 p.

  Research output: Contribution to journal › Conference article › peer-review

• Macrophagic Sclerostin Loop2-ApoER2 Interaction Required by Sclerostin for Suppressing Inflammatory Responses (Abstract)

  Wang, L., Zhang, N., Liu, J., Yang, X., Yu, Y., Li, D., Jiang, H., Sun, M., Li, N., Ma, D., Huang, Y., Lu, A., Zhang, B. & Zhang, G., May 2023, In: Metabolism: Clinical and Experimental. 142, Supplement, 1 p., 155427.

  Research output: Contribution to journal › Conference article › peer-review

• Sclerostin loop3-LRP4 Interaction Required by Sclerostin for Lipid and Glucose Metabolism Impairment in Adipocyte

  Jiang, H., Li, D., Wang, L., Zhang, N., Yu, S., Zhang, H., Liu, J., Ma, D., Lu, A., Sheng, H., Zhang, B. & Zhang, G., May 2023, In: Metabolism: Clinical and Experimental. 142, Supplement, 1 p., 155432.

  Research output: Contribution to journal › Conference article › peer-review

  • Lipid Metabolism 100%
  • Adipocytes 98%
  • Glucose 65%
  • Cardiovascular System 34%
  • Safety 20%

• Sclerostin Loop3 Participates in Whole-body Lipid and Glucose Metabolism Impairment Effects of Sclerostin (Abstract)

  Li, D., Jiang, H., Wang, L., Zhang, N., Yu, S., Zhang, H., LI, N., Liu, J., Ma, D., Lu, A., Sheng, H., Zhang, B. T. & Zhang, G., May 2023, In: Metabolism: Clinical and Experimental. 142, Supplement, 1 p., 155439.

  Research output: Contribution to journal › Conference article › peer-review

  • Lipid Metabolism 100%
  • Glucose 65%
  • Postmenopausal Osteoporosis 54%
  • Antibodies 24%
  • Type 2 Diabetes Mellitus 22%
• 2022

  Long Noncoding RNA Lnc-mar Contributes to the Maintenance of Skeletal Muscle Mass and Strength during Aging (abstract)

  Zhang, Z., Zhang, N., Yao, S., Jiang, H., Zhang, G. & Zhang, B., Feb 2022, In: Journal of Bone and Mineral Research. 37, Suppl 1, p. 182 1 p.

  Research output: Contribution to journal › Conference article › peer-review

  • Long Noncoding RNA 100%
  • Muscle Strength 94%
  • Sarcopenia 76%
  • Skeletal Muscle 73%
  • Maintenance 64%

• Pathogenetic Role of Gut Microbiota Shunting of Dietary Phenylalanine to Phenethylamine in Diarrhea-predominant Irritable Bowel Syndrome

  Zhai, L., Huang, C., Ning, Z., Zhang, Y., Zhuang, M., Yang, W., Wang, X., Wang, J., Zhang, E. L., Xiao, H., Zhao, L., Lam, Y. Y., Chow, C-F. W., Huang, J., Yuan, S., Chan, K-M., Yuan, C-S., Lau, J. Y-N., Wong, H-L. X. & Bian, Z-X., Sept 2022, In: Gut. 71, Suppl. 2, p. A33-A37 5 p.

  Research output: Contribution to journal › Conference article › peer-review

  • phenethylamine 100%
  • Irritable Bowel Syndrome 74%
  • Phenylalanine 71%
  • Gastrointestinal Microbiome 64%
  • Serotonin 55%

• Targeting 11β-HSD1 in osteoblasts reduces fat mass and prevents bone loss in mice with high-fat diet-induced obesity (abstract)

  Zhong, C., Li, N., Li, D., Wang, S., Zhang, H., Sun, M., Wang, Z., Xie, D., Wu, X., Li, F., Yu, S., Ma, Y., Dai, H., Amu, G., Lyu, A., Ren, F., Liu, J. & Zhang, G., Feb 2022, In: Journal of Bone and Mineral Research. 37, Suppl 1, p. 105 1 p.

  Research output: Contribution to journal › Conference article › peer-review
• 2020

  Elevated mature osteoblastic 11β-HSD1 contributes to high-fat-diet induced obesity (Abstract)

  Zhong, C., Wang, S., Liu, J., Dang, L., Li, D., Li, N., Dai, R., Zhang, H., Liang, C., Ni, S., Lyu, A., Ren, F., Zhou, H. & Zhang, G., Nov 2020, In: Journal of Bone and Mineral Research. 35, S1, p. 20 1 p., 1054.

  Research output: Contribution to journal › Conference article › peer-review

  Open Access

• Sclerostin loop3: a potential target for developing a next generation sclerostin inhibitor for bone anabolic therapy with low cardiovascular concern (Abstract)

  Yu, Y., Wang, L., Ni, S., Zhuo, Z., Chu, H. Y., Zhang, N., Li, D., Liu, J., Lyu, A., Zhang, B. T. & Zhang, G., Nov 2020, In: Journal of Bone and Mineral Research. 35, S1, p. 252 1 p., P-657.

  Research output: Contribution to journal › Conference article › peer-review

  Open Access

• Synthesis and in vitro evaluation of a bispecific aptamer targeting both Sclerostin and Dickkopf-1 (Abstract)

  Zhuo, Z., Ni, S., Zhang, Z., Zhang, N., Yu, Y., Lu, A., Zhang, G. & Zhang, B. T., Nov 2020, In: Journal of Bone and Mineral Research. 35, SI, p. 238 1 p., P-615.

  Research output: Contribution to journal › Conference article › peer-review

  Open Access
  1 Citation (Scopus)
• 2019

  625 – Donor Fungi and Bacteria Engraftment After Successful Eradication of Carbapenem-Resistant Enterobacteriaceae with Fecal Microbiota Transplantation: Serial Fecal Metagenomics Analysis (Extended Abstract)

  Liu, Q., Yang, K., Xu, Z., Zuo, T., Tang, W., Zhang, F., Lau, L. H. S., Lui, R. N. S., Wong, R., Chin, M. L., Chan, P. K., Chan, F. K., Lui, G. C. & Ng, S. C., May 2019, In: Gastroenterology. 156, 6, Supplement 1, p. S-131 1 p.

  Research output: Contribution to journal › Conference article › peer-review

• Altered Gut Microbiota Induce the Increased Excretion of Bile Acids in Patients with Diarrhea-Predominant Irritable Bowel Syndrome (Abstract)

  Zhao, L., Yang, W., Lu, L., Zhai, L., Zhong, L., Lam, W., Cheng, C. & Bian, Z., 18 May 2019, In: Gastroenterology. 156, 6, Supplement 1, p. S198-S198 1 p.

  Research output: Contribution to journal › Conference article › peer-review

  Open Access

• A potential next generation sclerostin inhibitor specifically targets sclerostin monomer for bone anabolic therapy with low ardiovascular risk in osteogenesis imperfecta mice (Abstract)

  Ren, Q., Xie, D., Yu, Y., Tang, Y., Ni, S., Lu, J., Lu, A., Zhang, G., Chan, S. Y. & Zhang, B. T., Dec 2019, In: Journal of Bone and Mineral Research. 34, S1, p. 47-48 2 p.

  Research output: Contribution to journal › Conference article › peer-review

• A Potential Next Generation Sclerostin Inhibitor Specifically Targets Sclerostin Monomer for Bone Anabolic Therapy with Low Cardiovascular Risk to Reverse Established Osteoporosis in Ovariectomized Rats (Abstract)

  Yu, Y., Ren, Q., Ni, S., Liu, J., Zhong, C., Lu, J., Tang, Y., Li, D., Xie, D., Dai, R., Zhang, H., Dang, L., Lyu, A., Zhang, G., Zhuo, Z., Zhang, Z-K., Zhang, B. T., Wang, L., Li, Y., Wong, K. K., & 1 othersZhai, J., Dec 2019, In: Journal of Bone and Mineral Research. 34, S1, p. 264 1 p.

  Research output: Contribution to journal › Conference article › peer-review

• Berberine Regulates Lysophosphatidylcholine to Protect Dss-Induced Murine Colitis Through Inhibition of Cytosolic Phospholipase A2 Activities (Abstract)

  Zhai, L., Lin, C., Zhao, L., Huang, T., Xiao, H. & Bian, Z., 18 May 2019, In: Gastroenterology. 156, 6, Supplement 1, p. S619-S620 2 p.

  Research output: Contribution to journal › Conference article › peer-review

  Open Access

• Diethyl Aminoethyl Hexanoate Increases Chicoric Acid Accumulation in Purple Coneflower (Echinacea purpurea L.) (Abstract)

  Chen, X., Li, D., Chen, H., Chen, Y., Yang, Y. & Wu, H., 22 Nov 2019, In: Basic and Clinical Pharmacology and Toxicology. 134, 3

  Research output: Contribution to journal › Conference article › peer-review

  Open Access

  • chicoric acid 100%
  • Chicoric Acid 99%
  • Echinacea 84%
  • Hexanoate 76%
  • Drop 18%

• From cytotoxic tumor-targeting to regulation of the tumor microenvironment: new considerations in pancreatic cancer chemotherapy (Abstract)

  Ko, J. K-S., May 2019, In: Journal of Cancer Science & Therapy. 11, p. 16 1 p.

  Research output: Contribution to journal › Conference article › peer-review

  Open Access

• LL-37 inhibits pancreatic cancer development through inhibition of autophagy and reprogramming of the tumor microenvironment (Poster, Extended abstract)

  Ko, J. K-S. & Zhang, Z., Mar 2019, In: European Journal of Cancer. 110, Supplement 1, p. S5-S6 2 p.

  Research output: Contribution to journal › Conference article › peer-review

  Open Access

• Long-term osteoblast-specific Plekho1 silencing by RNA interference prevents bone formation reduction during aging in safety in both genders (Abstract)

  Zhang, Z., Zhuo, Z., Zhang, B-T., Liu, J., Liang, C., Lu, A. & Zhang, G., 23 Sept 2019, In: Journal of Bone and Mineral Research. 34, S1, p. 370-370 1 p.

  Research output: Contribution to journal › Conference article › peer-review

  Open Access

  • RNA Interference 100%
  • Osteoblasts 99%
  • Osteogenesis 91%
  • Safety 60%
  • Osteoporosis 27%
  3 Citations (Scopus)

• PARP1 interacts with ezrin contributing to metastasis in osteosarcoma

  Li, F., Wu, X., Fu, X., Lu, A., Zhang, G. & Lim, N. J., Dec 2019, In: Journal of Bone and Mineral Research. 34, S1, p. 133 1 p.

  Research output: Contribution to journal › Conference article › peer-review

• Targeting a newly identified lncRNA and its interaction with HuR to promote osteogenic cells migration to bone formation surface for reversing established age-related osteoporosis (Abstract)

  Li, D., Yang, C., Zhihao, C., Zhao, F., Qian, A., Liu, J., Liang, C., Guan, D., Ni, S., Ren, Q., Tang, Y., Wu, X., Lu, A. & Zhang, G., Dec 2019, In: Journal of Bone and Mineral Research. 34, S1, p. 333-333 1 p.

  Research output: Contribution to journal › Conference article › peer-review

  Open Access

  • Ficus 100%
  • Long Noncoding RNA 85%
  • Osteoporosis 69%
  • Osteogenesis 69%
  • Cell Movement 64%

• Therapeutic potential of henryin in the treatment of pancreatic cancer (Abstract)

  Ko, J. K-S., May 2019, In: Journal of Cancer Science & Therapy. 11, p. 32 1 p.

  Research output: Contribution to journal › Conference article › peer-review

  Open Access
• 2017

  Combating Colon Cancer through Modulation of the Tumor Microenvironment and Gut Microbiota (Abstract)

  Ko, J. K., Apr 2017, In: FASEB Journal. 31, S1, p. 824.14 1 p.

  Research output: Contribution to journal › Conference article › peer-review

  • Tumor Microenvironment 100%
  • Gastrointestinal Microbiome 95%
  • Colonic Neoplasms 87%
  • Antineoplastic Agent 85%
  • Cancer-Associated Fibroblasts 74%

• Inhibitors of store-operated calcium entry (SOCE) attenuate S100A4-mediated metastatic progression in liver metastases of colon cancer (Abstract)

  Ko, J., Dec 2017, In: Clinical and Experimental Metastasis. 34, 8, p. 507 1 p.

  Research output: Contribution to journal › Conference article › peer-review
• 2016

  A study in general education: How a field trip for Chinese tea tasting motivates students’ learning

  Nie, S., Chong, K. & Li, M., Jan 2016, In: International Journal of Humanities, Social Sciences and Education. 3, 1, p. 125-135 11 p.

  Research output: Contribution to journal › Conference article › peer-review

  Open Access

  • general education 100%
  • learning motivation 42%
  • learning 33%
  • student 24%
  • Hong Kong 10%
• 2015

  AST is a novel anti-carcinogenic regimen against gastrointestinal cancer development with unique molecular targets (Abstract)

  Ko, J. & Auyeung, K. K. W., 21 Jul 2015, In: Journal of Gastrointestinal and Digestive System. 5, 3, p. 50 1 p.

  Research output: Contribution to journal › Conference article › peer-review

  Open Access

  • Anticarcinogenic 100%
  • Antineoplastic Agent 61%
  • Immunomodulating Agent 40%
  • Antimetastatic 35%
  • Tumor Marker 30%

• Protopine, a promising novel histone deacetylase 6 inhibitor reduces tauopathy in in vitro and in vivo

  Durairajan, S. S. K., Li, M., Malampatti, S., Zhang, Y., Liu, L. F., Song, J., Chen, L. L., Zeng, Y. & Senapati, S., Mar 2015, In: Neurodegenerative Diseases. 15, Suppl. 1, p. 1579 1 p.

  Research output: Contribution to journal › Conference article

  Open Access

• Tanshinones modulate the development of colon cancer through regulation of calpains and calcium homeostasis (Extended Abstract)

  Ko, J., Au Yeung, K. & Wang, Y., Sept 2015, In: European Journal of Cancer. 51, Supplement 3, p. S334 1 p.

  Research output: Contribution to journal › Conference article › peer-review
• 2014

  Anticancer Drug Discovery Based on Plant Biodiversity (Abstract)

  Zhang, H., Liu, K. & Guan, Y., 6 Oct 2014, In: Anticancer Research. 34, 10, p. 6253-6254 2 p.

  Research output: Contribution to journal › Conference article › peer-review

  Open Access

  • Biodiversity 100%
  • Plant Extracts 85%
  • Drug Discovery 75%
  • Inhibitory Concentration 50 65%
  • Biological Products 53%

• Bilirubin Increased by Heme Oxygenase-1 Induction Improves Endothelial Function in Diabetic Mice

  Liu, J., Wang, L., Tian, X-Y., Liu, L., Wong, W-T., Zhang, Y., Han, Q., Ho, H-M., Wang, N., Wong, S-L., Chen, Z., Yu, J., Yao, X. & Huang, Y., 24 Sept 2014, In: Journal of Atherosclerosis and Thrombosis. 21, Supplement 3, p. S34 1 p.

  Research output: Contribution to journal › Conference article › peer-review

  Open Access

• Ckip-1 in osteoblasts plays an inhibition role in bone formation in aged male osteoporosis

  Guo, B., Liu, J., Lyu, A., Zhang, B. & Zhang, G., May 2014, In: Molecular Therapy. 22, Supplement 1, p. S39-S40 2 p.

  Research output: Contribution to journal › Conference article

  Open Access

• Regulation of calpain-mediated glucose-regulated protein modulates colon cancer development (Abstract)

  Ko, J. K., Auyeung, K. K. & Wang, Y., 20 Oct 2014, In: Journal of Cancer Science & Therapy. 6, 10, p. 116 1 p.

  Research output: Contribution to journal › Conference article › peer-review

  Open Access

  • glucose-regulated proteins 100%
  • Calpain 89%
  • Colonic Neoplasms 65%
  • Endoplasmic Reticulum Stress 24%
  • Apoptosis 21%
• 2013

  Anti-tumor and anti-metastatic potential of ast with attenuated hematologic side effects of chemotherapeutic drugs in human colon cancer (abstract)

  Ko, K. S. J. & Au Yeung, K. W., May 2013, In: Gastroenterology. 144, 5, Supplement 1, p. S290-S291 2 p.

  Research output: Contribution to journal › Conference article › peer-review

  Open Access
• 2012

  Aptamer facilitates osteogenic sirnas specifically targeting osteoblast and reducing their exporsure to hepatocyte in vivo

  Liang, C., Wu, H., Guo, B., Zhang, L., Lyu, A. & Zhang, G., Dec 2012, In: Osteoporosis International. 23, 7 supplement, p. S761-S762 2 p.

  Research output: Contribution to journal › Conference article

• Can bone erosion in Rheumatoid arthritis be repaired by current therapeutics? The past, the present and the future

  Jiang, M., Zhang, C., Li, J., Yang, J., Zhang, G. & Lyu, A., Dec 2012, In: Osteoporosis International. 23, 7 supplement, p. S821-S821 1 p.

  Research output: Contribution to journal › Conference article

• Electroacupuncture is better than cox-2 inhibitor celecoxib for neuropathic pain in rat

  Zhang, H. Q., Lau, W. K., Lau, Y. M., Wong, S. C. & Yip, T. P., 6 Jan 2012, In: European Journal of Pain Supplements. 4, S1, p. 63-64 2 p.

  Research output: Contribution to journal › Conference article › peer-review

• P159 Astragalus saponins inhibit LPS-induced inflammatory effects in macrophages

  Ko, K. S. J. & Au Yeung, K. W., Sept 2012, In: Cytokine. 59, 3, p. 570-571 2 p.

  Research output: Contribution to journal › Conference article › peer-review

  Open Access

• Traditional Chinese medicine for irritable bowel syndrome: From classic formula to modern medicine development

  Bian, Z., Jun 2012, In: Journal of Translational Medicine. 10, Supplement 2, 30230.

  Research output: Contribution to journal › Conference article

  Open Access
• 2011

  Complementary and alternative therapies in the treatment of inflammatory bowel disease: a systematic review of human studies

  Ng, S. C., Tsoi, K. K. F., Lam, Y. T., Bian, Z., Lao, L. X., Berman, B., Che, C. T., Sung, J. J. Y. & Wu, J. C. Y., Oct 2011, In: Journal of Gastroenterology and Hepatology. 26, S5, p. 106-106 1 p.

  Research output: Contribution to journal › Conference article

  Open Access
• 2010

  437 The synergistic antitumorigenic effects of vinblastine and total Astragalus saponins (AST) with reduced invasiveness of colon cancer cells

  Ko, K. S. J., Au Yeung, K. W. & Law, P. C., Nov 2010, In: European Journal of Cancer. 8, 7 Suppl, p. 138 1 p.

  Research output: Contribution to journal › Conference article › peer-review

• Biomarkers discovery for evidence-based Chinese medicines using the proteomic technology platform

  Tai, C. S., Wong, W. Y., Chiu, J. F. & Hsiao, W. W., Apr 2010, In: New Biotechnology. 27, Supplement 1, p. S74 1 p.

  Research output: Contribution to journal › Conference article

• The combined effect of salvianolic acid B and laminar shear stress on TNF-α-stimulated adhesion molecule expression in human aortic endothelial cells

  Li, M., Xie, L. X., Durairajan, S. S. K., Lu, J. H., Liu, L. F., Wang, Y., Wu, W. K., Han, D. & Liao, F., 14 Jun 2010, In: Circulation. 122, 2, 13611.

  Research output: Contribution to journal › Conference article

  Open Access
• 2008

  Astragalus saponins (AST) modulate mTOR and ERK signaling with NF-kappa B as target in native and cytokine-induced HT-29 colon cancer cells (Poster Abstract)

  Ko, J. K. S., Mok, N. L., Wong, C. M. & Auyeung, K. K. W., Oct 2008, In: European Journal of Cancer Supplements. 6, 12, p. 179-180 2 p.

  Research output: Contribution to journal › Conference article › peer-review
• 2007

  Astragalus saponins induce transcriptional activation of NSAID-activated gene (NAG-1) in colon cancer cells via a PI3K-Akt/Egr-1 signaling pathway (Abstract)

  Ko, J. K., Auyeung, K. K., Tin, M. M. & Cho, C., Apr 2007, In: Gastroenterology. 132, 4, Supplement 2, p. A423 1 p.

  Research output: Contribution to journal › Conference article › peer-review

  Open Access