School of Chinese Medicine

2025

Bromelain hydrolysis and CaCl₂ coordination promote the fibrillation of quinoa protein at pH 7

Fu, L., Feng, X., Wu, C., Wei, J., Chen, L., Yu, X., Liu, Q. & Tang, X., Feb 2025, In: Food Hydrocolloids. 159, 110659.

Research output: Contribution to journal › Journal article › peer-review

1 Citation (Scopus)

2024

20(S)-Ginsenoside Rh2 induces apoptosis and autophagy in melanoma cells via suppressing Src/STAT3 signaling

Li, J. K., Jiang, X. L., Zhang, Z., Chen, W. Q., Peng, J. J., Liu, B., Yung, K. K. L. & Zhu, P. L., Nov 2024, In: Journal of Ginseng Research. 48, 6, p. 559-569 11 p.

Research output: Contribution to journal › Journal article › peer-review

Open Access

6PPD-quinone exposure induces neuronal mitochondrial dysfunction to exacerbate Lewy neurites formation induced by α-synuclein preformed fibrils seeding

Fang, J., Wang, X., Cao, G., Wang, F., Ru, Y., Wang, B., Zhang, Y., Zhang, D., Yan, J., Xu, J., Ji, J., Ji, F., Zhou, Y., Guo, L., Li, M., Liu, W., Cai, X. & Cai, Z., 5 Mar 2024, In: Journal of Hazardous Materials. 465, 133312.

Research output: Contribution to journal › Journal article › peer-review

19 Citations (Scopus)

Abietane diterpenoids from Isodon amethystoides and their biological activities

Zhou, L., Zhao, C. L., Xu, C. Y., Dong, M. H., Ye, J. H., Zhang, J. J., Pan, L. T., Zou, J. & Zhang, H. J., Sept 2024, In: Phytochemistry. 225, 10 p., 114171.

Research output: Contribution to journal › Journal article › peer-review

A cross-disease, pleiotropy-driven approach for therapeutic target prioritization and evaluation

Bao, C., Tan, T., Wang, S., Gao, C., Lu, C., Yang, S., Diao, Y., Jiang, L., Jing, D., Chen, L., Lv, H. & Fang, H., 22 Apr 2024, In: Cell Reports Methods. 4, 4, 21 p., 100757.

Research output: Contribution to journal › Journal article › peer-review

Open Access

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1 Citation (Scopus)

43 Downloads (Pure)

Activation of APE1 modulates Nrf2 protected against acute liver injury by inhibit hepatocyte ferroptosis and promote hepatocyte autophagy

Diao, J., Fan, H., Zhang, J., Fu, X., Liao, R., Zhao, P., Huang, W., Huang, S., Liao, H., Yu, J., Pan, D., Wang, M., Xiao, W. & Wen, X., 20 Feb 2024, In: International Immunopharmacology. 128, 11 p., 111529.

Research output: Contribution to journal › Journal article › peer-review

Open Access

Activation of hepatic adenosine A1 receptor ameliorates MASH via inhibiting SREBPs maturation

Zhu, W., Hong, Y., Tong, Z., He, X., Li, Y., Wang, H., Gao, X., Song, P., Zhang, X., Wu, X., Tan, Z., Huang, W., Liu, Z., Bao, Y., Ma, J., Zheng, N., Xie, C., Ke, X., Zhou, W. & Jia, W. & 4 others, Li, M., Zhong, J., Sheng, L. & Li, H., 19 Mar 2024, In: Cell Reports Medicine. 5, 3, 28 p., 101477.

Research output: Contribution to journal › Journal article › peer-review

Open Access

1 Citation (Scopus)

Add-on astragalus in type 2 diabetes and chronic kidney disease: A multi-center, assessor-blind, randomized controlled trial

Chan, K. W., Kwong, A. S. K., Tsui, P. N., Chan, G. C. W., Choi, W. F., Yiu, W. H., Cheung, S. C. Y., Wong, M. M. Y., Zhang, Z. J., Tan, K. C. B., Lao, L., Lai, K. N., Tang, S. C. W. & READY and SCHEMATIC research group, 25 Jul 2024, In: Phytomedicine. 130, 11 p., 155457.

Research output: Contribution to journal › Journal article › peer-review

1 Citation (Scopus)

ADMETlab 3.0: an updated comprehensive online ADMET prediction platform enhanced with broader coverage, improved performance, API functionality and decision support

Fu, L., Shi, S., Yi, J., Wang, N., He, Y., Wu, Z., Peng, J., Deng, Y., Wang, W., Wu, C., Lyu, A., Zeng, X., Zhao, W., Hou, T. & Cao, D., 5 Jul 2024, In: Nucleic Acids Research. 52, W1, p. W422-W431 10 p.

Research output: Contribution to journal › Journal article › peer-review

Open Access

49 Citations (Scopus)

Advancing targeted combination chemotherapy in triple negative breast cancer: nucleolin aptamer-mediated controlled drug release

Ma, Y., Xie, D., Chen, Z., Shen, X., Wu, X., Ding, F., Ding, S., Pan, Y., Li, F., Lu, A. & Zhang, G., 1 Jul 2024, In: Journal of Translational Medicine. 22, 1, 13 p., 604.

Research output: Contribution to journal › Journal article › peer-review

Open Access

1 Citation (Scopus)

Aloperine Suppresses Cancer Progression by Interacting with VPS4A to Inhibit Autophagosome-lysosome Fusion in NSCLC

Guo, W., Zhou, H., Wang, J., Lu, J., Dong, Y., Kang, Z., Qiu, X., Ouyang, X., Chen, Q., Li, J., Cheng, X., Du, K., Li, M., Lin, Z., Jin, M., Zhang, L., Sarapultsev, A., Shi, K., Li, F. & Zhang, G. & 8 others, Wu, K., Rong, Y., Heissmeyer, V., Liu, Y., Li, Y., Huang, K., Luo, S. & Hu, D., 21 Aug 2024, In: Advanced Science. 11, 31, 21 p., 2308307.

Research output: Contribution to journal › Journal article › peer-review

Open Access

A Novel Multiple-Network Analysis Integrating Metabolomics and Pharmacology for Mechanism Study of Medicine: A Case Study of CDD-2101 Against Constipation

Shi, J., Xiang, L., Lam, Y. Y., Ning, Z., Liu, J., Li, Y., Zhou, Y., Zhai, L., Lin, C., Zhu, L. & Bian, Z., Dec 2024, In: Journal of Analysis and Testing. 8, 4, p. 415–430 16 p.

Research output: Contribution to journal › Journal article › peer-review

Open Access

1 Citation (Scopus)

A novel network pharmacology strategy to decode mechanism of Wuling Powder in treating liver cirrhosis

Liu, Q., Li, X., Li, Y., Luo, Q., Fan, Q., Lu, A., Guan, D. & Li, J., 1 Mar 2024, In: Chinese Medicine (United Kingdom). 19, 1, 17 p., 36.

Research output: Contribution to journal › Journal article › peer-review

Open Access

Aptamer AS411 interacts with the KRAS promoter/hnRNP A1 complex and shows increased potency against drug-resistant lung cancer

Zhu, Y., Li, X., Zhang, Q., Yang, X., Sun, X., Pan, Y., Yuan, X., Ma, Y., Xu, B. & Yang, Z., 1 May 2024, In: RSC Medicinal Chemistry. 15, 5, p. 1515-1526 12 p.

Research output: Contribution to journal › Journal article › peer-review

Aptamer Functionalized Hypoxia-potentiating Agent and Hypoxia-inducible Factor Inhibitor Combined with Hypoxia-activated Prodrug for Enhanced Tumor Therapy

Ma, Y., Zhang, H., Shen, X., Yang, X., Deng, Y., Tian, Y., Chen, Z., Pan, Y., Luo, H., ZHONG, C., Yu, S., Lu, A., Zhang, B., Tang, T. & Zhang, G., 28 Aug 2024, In: Cancer Letters. 598, 12 p., 217102.

Research output: Contribution to journal › Journal article › peer-review

Open Access

2 Citations (Scopus)

Aptamer-functionalized triptolide with release controllability as a promising targeted therapy against triple-negative breast cancer

Chen, Y., Yang, J., Wang, C., Wang, T., Zeng, Y., Li, X., Zuo, Y., Chen, H., Zhang, C., Cao, Y., Sun, C., Wang, M., Cao, X., Ge, X., Liu, Y., Zhang, G., Deng, Y., Peng, C., Lu, A. & Lu, J., 25 Jul 2024, In: Journal of Experimental and Clinical Cancer Research. 43, 1, 18 p., 207.

Research output: Contribution to journal › Journal article › peer-review

Open Access

2 Citations (Scopus)

Are Tai Chi and Qigong effective in the treatment of traumatic brain injury? A systematic review

Laskosky, N. A., Huston, P., Lam, W. C., Anderson, C. & Zhong, L. L. D., 6 Feb 2024, In: BMC Complementary Medicine and Therapies. 24, 1, 13 p., 78.

Research output: Contribution to journal › Journal article › peer-review

Open Access

Artesunate treats obesity in male mice and non-human primates through GDF15/GFRAL signalling axis

Guo, X., Asthana, P., Zhai, L., Cheng, K. W., Gurung, S., Huang, J., Wu, J., Zhang, Y., Mahato, A. K., Saarma, M., Ustav, M., Kwan, H. Y., Lyu, A., Chan, K. M., Xu, P., Bian, Z. X. & Wong, H. L. X., 3 Feb 2024, In: Nature Communications. 15, 1, 14 p., 1034.

Research output: Contribution to journal › Journal article › peer-review

Open Access

5 Citations (Scopus)

Artificial intelligence with mass spectrometry-based multimodal molecular profiling methods for advancing therapeutic discovery of infectious diseases

Liu, J., Bao, C., Zhang, J., Han, Z., Fang, H. & Lu, H., Nov 2024, In: Pharmacology and Therapeutics. 263, 108712.

Research output: Contribution to journal › Journal article › peer-review

Aspartame Causes Developmental Defects and Teratogenicity in Zebra Fish Embryo: Role of Impaired SIRT1/FOXO3a Axis in Neuron Cells

Pandaram, A., Paul, J., Wankhar, W., Thakur, A., Verma, S., Vasudevan, K., Wankhar, D., Kammala, A. K., Sharma, P., Jaganathan, R., Iyaswamy, A. & Rajan, R., Apr 2024, In: Biomedicines. 12, 4, 19 p., 855.

Research output: Contribution to journal › Journal article › peer-review

Open Access

4 Citations (Scopus)

Assessing the influence of latency variability on EEG classifiers - a case study of face repetition priming

Li, Y., Sommer, W., Tian, L. & Zhou, C., 21 Oct 2024, (E-pub ahead of print) In: Cognitive Neurodynamics. 15 p.

Research output: Contribution to journal › Journal article › peer-review

Open Access

Assessment of Spatial Variability of Polycyclic Aromatic Hydrocarbons (PAHs) in Urban Soils and Fungal Disease Status of Trees Grown in Hong Kong Areas

Sung, K. C., Leung, H. M., Lee, C. F., Fatemeh, T., Mo, W. Y., Woo, L. Y., Cheung, K. C., Ogbonnaya, U., Yung, K. K. L. & Li, W. C., Dec 2024, In: International Journal of Environmental Research. 18, 6, 14 p., 101.

Research output: Contribution to journal › Journal article › peer-review

Associations between fine particulate matter and colorectal cancer: a systematic review and meta-analysis

Fu, P., Li, R., Sze, S. C. W. & Yung, K. K. L., 25 Sept 2024, In: Reviews on Environmental Health. 39, 3, p. 447-457 11 p.

Research output: Contribution to journal › Journal article › peer-review

2 Citations (Scopus)

A systematic approach for authentication of medicinal Patrinia species using an integration of morphological, chemical and molecular methods

Wong, K.-H., Zhang, T., Yue, G. G. L., Li, M.-C., Wu, H. Y., Tong, M. H., Zhao, X.-L., Chen, H., Lau, C. B. S., Shaw, P. C. & Lau, D. T. W., 19 Mar 2024, In: Scientific Reports. 14, 1, 14 p., 6566.

Research output: Contribution to journal › Journal article › peer-review

Open Access

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1 Citation (Scopus)

20 Downloads (Pure)

Atractylenolide II combined with Interferon-γ synergistically ameliorates colorectal cancer progression in vivo and in vitro by blocking the NF-kB p65/PD-L1 pathway

Wu, Y., Dai, S., Zhang, Y. J., Li, Z., Zhu, B., Liu, Q., Wo, L., Yu, Z., Yuan, X. & Dou, X., 11 Jun 2024, In: Journal of Cancer. 15, 13, p. 4328-4344 17 p.

Research output: Contribution to journal › Journal article › peer-review

Open Access

Bile acid signaling in the regulation of whole body metabolic and immunological homeostasis

Jia, W., Li, Y., Cheung, K. C. P. & Zheng, X., May 2024, In: Science China Life Sciences. 67, 5, p. 865–878 14 p.

Research output: Contribution to journal › Journal article › peer-review

29 Citations (Scopus)

BindingSiteDTI: differential-scale binding site modelling for drug–target interaction prediction

Pan, F., Yin, C., Liu, S. Q., Huang, T., Bian, Z. & Yuen, P. C., May 2024, In: Bioinformatics. 40, 5, 8 p., btae308.

Research output: Contribution to journal › Journal article › peer-review

Open Access

Biotin-decorated celastrol-loaded ZIF-8 nanoparticles induce ferroptosis for colorectal cancer therapy

Chen, J., Liu, Y., You, Y., Zhou, R., Li, Y., Zhou, X., Chen, X., Yang, Y., Chen, J., Kwan, H. Y., Zhao, X. & Wu, Y., Mar 2024, In: Materials and Design. 239, 13 p., 112814.

Research output: Contribution to journal › Journal article › peer-review

Open Access

2 Citations (Scopus)

Bridging the Gap: A Comprehensive Study on Traditional Chinese Medicine Strategies for Managing Adult Irritable Bowel Syndrome

Wei, D. J., Li, H. J., Lyu, A. P., Bian, Z. X., Siah, K. T. H. & Zhong, L. L. D., 30 Sept 2024, (E-pub ahead of print) In: American Journal of Chinese Medicine. 52, 6, p. 1-23 23 p.

Research output: Contribution to journal › Journal article › peer-review

Carrier-free self-assembled nanomedicine based on celastrol and galactose for targeting therapy of hepatocellular carcinoma via inducing ferroptosis

Zhang, X., Chen, Y., Li, X., Xu, H., Yang, J., Wang, C., Zhang, C., Deng, Y., Lu, A., Zheng, C. & Lu, J., 5 Mar 2024, In: European Journal of Medicinal Chemistry. 267, 14 p., 116183.

Research output: Contribution to journal › Journal article › peer-review

15 Citations (Scopus)

Case report: Staged tension-reducing excision of giant acquired vulvar lymphangioma secondary to cervical cancer surgery

Hu, L. J., Fang, H. M., Lin, H. M., Kang, X., Lin, Y. & Xiao, J., 6 Sept 2024, In: Frontiers in Oncology. 14, 5 p., 1418829.

Research output: Contribution to journal › Journal article › peer-review

Open Access

CD31 orchestrates metabolic regulation in autophagy pathways of rheumatoid arthritis

Cheung, K. C. P., Ma, J., Wang, L., Chen, X., Fanti, S., Li, M., Azevedo, L. R., Gosselet, F., Shen, H., Zheng, X., Lu, A. & Jia, W., Sept 2024, In: Pharmacological Research. 207, 12 p., 107346.

Research output: Contribution to journal › Journal article › peer-review

Open Access

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Centipeda minima (L.) A. Braun & Asch. and its representative active compound alleviate DSS-induced ulcerative colitis via inhibition of NLRP3 inflammasome activation and regulation of gut microbiota

Tan, J., Wang, S., Gan, S., Chen, H., Zhong, K., Kwan, H. Y., Fan, X., Xiao, B., Liang, Q., Liu, Z. & Su, T., Jun 2024, In: Journal of Functional Foods. 117, 12 p., 106207.

Research output: Contribution to journal › Journal article › peer-review

Open Access

ChemFH: an integrated tool for screening frequent false positives in chemical biology and drug discovery

Shi, S., Fu, L., Yi, J., Yang, Z., Zhang, X., Deng, Y., Wang, W., Wu, C., Zhao, W., Hou, T., Zeng, X., Lyu, A. & Cao, D., 5 Jul 2024, In: Nucleic Acids Research. 52, W1, p. W439–W449 11 p.

Research output: Contribution to journal › Journal article › peer-review

Open Access

ChemMORT: an automatic ADMET optimization platform using deep learning and multi-objective particle swarm optimization

Yi, J. C., Yang, Z. Y., Zhao, W. T., Yang, Z. J., Zhang, X. C., Wu, C. K., Lu, A. P. & Cao, D. S., Mar 2024, In: Briefings in Bioinformatics. 25, 2, 10 p., bbae008.

Research output: Contribution to journal › Journal article › peer-review

Open Access

3 Citations (Scopus)

Chinese herbal medicine combined with Western medicine for Mycoplasma pneumoniae pneumonia in children: An overview of systematic reviews

Zhang, S., Zhang, X., Cui, Y., Huang, J., Fan, F., Wang, S. & Han, F., Jan 2024, In: Journal of Traditional Chinese Medical Sciences. 11, 1, p. 131-139 9 p.

Research output: Contribution to journal › Journal article › peer-review

Open Access

Comparation of abdominal aortic balloon occlusion versus uterine artery embolization in the treatment of cesarean scar pregnancy

Rui, T., Wei, H., Huaibo, J., Han, M., Cheung, K. C. P. & Yang, C., 25 Oct 2024, In: Frontiers in Medicine. 11, 8 p., 1472239.

Research output: Contribution to journal › Journal article › peer-review

Open Access

Corynoxine promotes TFEB/TFE3-mediated autophagy and alleviates Aβ pathology in Alzheimer’s disease models

Guan, X.-J., Deng, Z.-Q., Liu, J., Su, C.-F., Tong, B. C. K., Zhu, Z., Sreenivasmurthy, S. G., Kan, Y.-X., Lu, K., Chu, C. P. K., Pi, R.-B., Cheung, K.-H., Iyaswamy, A., Song, J.-X. & Li, M., May 2024, In: Acta Pharmacologica Sinica. 45, 5, p. 900–913 14 p.

Research output: Contribution to journal › Journal article › peer-review

9 Citations (Scopus)

CRISPRa engineered Elite macrophages enable adoptive cell therapy for rheumatoid arthritis

Huang, Y., Wang, Z., Zhong, C., Chen, H., Chen, X., Cao, C., Qiu, F., Xie, D., Li, J., Li, J., Yang, X., Lu, A., Fu, X. & Liang, C., 20 Mar 2024, In: The Innovation Medicine. 2, 1, 20 p., 100050.

Research output: Contribution to journal › Journal article › peer-review

Open Access

Critical review on the research of chemical structure, bioactivities, and mechanism of actions of Dendrobium officinale polysaccharide

Lai, C. H., Huo, C. Y., Xu, J., Han, Q. B. & Li, L. F., Apr 2024, In: International Journal of Biological Macromolecules. 263, 12 p., 130315.

Research output: Contribution to journal › Journal article › peer-review

8 Citations (Scopus)

Design and synthesis of nucleotidyl lipids and their application in the targeted delivery of siG12D for pancreatic cancer therapy

Pan, Y., Zhu, Y., Ma, Y., Hong, J., Zhao, W., Gao, Y., Guan, J., Ren, R., Zhang, Q., Yu, J., Guan, Z. & Yang, Z., Mar 2024, In: Biomedicine and Pharmacotherapy. 172, 14 p., 116239.

Research output: Contribution to journal › Journal article › peer-review

Open Access

1 Citation (Scopus)

Design of clinical trials in integrative medicine: The issue of personalization

Chan, K. W., Liu, J. P. & Bian, Z. X., Jun 2024, In: European Journal of Integrative Medicine. 68, 102365.

Research output: Contribution to journal › Journal article › peer-review

2 Citations (Scopus)

Determination of mycobiota and aflatoxin contamination in commercial bee pollen from eight provinces and one autonomous region of China

Guo, M., Zhang, J., Wang, Y., Chen, H., Lv, J., Kong, D., Jin, Z., Ke, T., Zhang, H., Luo, J. & Yang, M., 2 Feb 2024, In: International Journal of Food Microbiology. 411, 110511.

Research output: Contribution to journal › Journal article › peer-review

1 Citation (Scopus)

Developing Stapled Aptamers with a Constrained Conformation for Osteogenesis Imperfect Therapeutics

Gubu , A., Zhang, G., Jing, N. & Ma, Y., 14 Nov 2024, In: Journal of Medicinal Chemistry. 67, 21, p. 18883–18894 12 p.

Research output: Contribution to journal › Journal article › peer-review

Development of a therapeutic monoclonal antibody against circulating adipocyte fatty acid binding protein to treat ischaemic stroke

Liao, B., Yang, S., Geng, L., Zong, J., Zhang, Z., Jiang, M., Jiang, X., Li, S., Xu, A., Chang, J. & Hoo, R. L. C., Apr 2024, In: British Journal of Pharmacology. 181, 8, p. 1238-1255 18 p.

Research output: Contribution to journal › Journal article › peer-review

Open Access

2 Citations (Scopus)

Dietary ellagic acid therapy for CNS autoimmunity: Targeting on Alloprevotella rava and propionate metabolism

Han, B., Shi, L., Bao, M. Y., Yu, F. L., Zhang, Y., Lu, X. Y., Wang, Y., Li, D. X., Lin, J. C., Jia, W., Li, X. & Zhang, Y., 24 Jun 2024, In: Microbiome. 12, 1, 18 p., 114.

Research output: Contribution to journal › Journal article › peer-review

Open Access

2 Citations (Scopus)

Discovery of plasma biomarkers for Parkinson's disease diagnoses based on metabolomics and lipidomics

Wang, X., Wang, B., Ji, F., Yan, J., Fang, J., Zhang, D., Xu, J., Ji, J., Hao, X., Luan, H., Hong, Y., Qiu, S., Li, M., Yang, Z., Liu, W., Cai, X. & Cai, Z., Nov 2024, In: Chinese Chemical Letters. 35, 11, 109653.

Research output: Contribution to journal › Journal article › peer-review

1 Citation (Scopus)

Discovery of the small molecular inhibitors against sclerostin loop3 as potential anti-osteoporosis agents by structural based virtual screening and molecular design

Yu, S., Huang, W., Zhang, H., Guo, Y., Zhang, B., Zhang, G. & Lei, J., 5 May 2024, In: European Journal of Medicinal Chemistry. 271, 9 p., 116414.

Research output: Contribution to journal › Journal article › peer-review

2 Citations (Scopus)

DNA methylation of miR-181a-5p mediated by DNMT3b drives renal interstitial fibrosis developed from acute kidney injury

Liu, H., Deng, Y., Luo, G., Yang, Y., Xie, B., Diao, H., Chen, M., Chen, L., Xie, P., Kwan, H. Y., Zhao, X. & Sun, X., Sept 2024, In: Epigenomics. 16, 13, p. 945-960 16 p.

Research output: Contribution to journal › Journal article › peer-review

Open Access

Does the Dose of Standard Adjuvant Chemotherapy Affect the Triple-negative Breast Cancer Benefit from Extended Capecitabine Metronomic Therapy? An Exploratory Analysis of the SYSUCC-001 Trial

Chen, Y., Li, W. X., Wu, J. H., Chen, G. H., Yang, C. M., Lu, H., Wang, X., Wang, S. S., Huang, H., Cai, L., Zhao, L., Peng, R. J., Lin, Y., Tang, J., Zeng, J., Zhang, L. H., Ke, Y. L., Wang, X. M., Liu, X. M. & Zhang, A. Q. & 21 others, Xu, F., Bi, X. W., Huang, J. J., Li, J. B., Pang, D. M., Xue, C., Shi, Y. X., He, Z. Y., Lin, H. X., An, X., Xia, W., Cao, Y., Guo, Y., Hong, R. X., Jiang, K. K., Zhong, Y. Y., Zhang, G., Tienchaiananda, P., Oikawa, M., Yuan, Z. Y. & Chen, Q. J., 12 Apr 2024, In: Breast Cancer: Targets and Therapy. 16, p. 223-231 9 p.

Research output: Contribution to journal › Journal article › peer-review

Open Access

2 Citations (Scopus)

School of Chinese Medicine

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