Office of the Dean of Chinese Medicine

2024

Bridging the Gap: A Comprehensive Study on Traditional Chinese Medicine Strategies for Managing Adult Irritable Bowel Syndrome

Wei, D. J., Li, H. J., Lyu, A. P., Bian, Z. X., Siah, K. T. H. & Zhong, L. L. D., 30 Sept 2024, In: American Journal of Chinese Medicine. 52, 6, p. 1589-1611 23 p.

Research output: Contribution to journal › Journal article › peer-review

ChemFH: an integrated tool for screening frequent false positives in chemical biology and drug discovery

Shi, S., Fu, L., Yi, J., Yang, Z., Zhang, X., Deng, Y., Wang, W., Wu, C., Zhao, W., Hou, T., Zeng, X., Lyu, A. & Cao, D., 5 Jul 2024, In: Nucleic Acids Research. 52, W1, p. W439–W449 11 p.

Research output: Contribution to journal › Journal article › peer-review

Open Access

Corynoxine promotes TFEB/TFE3-mediated autophagy and alleviates Aβ pathology in Alzheimer’s disease models

Guan, X.-J., Deng, Z.-Q., Liu, J., Su, C.-F., Tong, B. C. K., Zhu, Z., Sreenivasmurthy, S. G., Kan, Y.-X., Lu, K., Chu, C. P. K., Pi, R.-B., Cheung, K.-H., Iyaswamy, A., Song, J.-X. & Li, M., May 2024, In: Acta Pharmacologica Sinica. 45, 5, p. 900–913 14 p.

Research output: Contribution to journal › Journal article › peer-review

9 Citations (Scopus)

Dissecting the anti-obesity components of ginseng: How ginseng polysaccharides and ginsenosides target gut microbiota to suppress high-fat diet-induced obesity

Luo, H.-Y., Fang, J., Zhang, W.-H., Chan, K.-C., Chan, Y.-M., Dong, C. X., Li, S. L., Lyu, A.-P. & Xu, J., 11 Dec 2024, (E-pub ahead of print) In: Journal of Advanced Research. 18 p.

Research output: Contribution to journal › Journal article › peer-review

Open Access

Exploring fructose metabolism as a potential therapeutic approach for pancreatic cancer

Wang, C., Wang, L., Zhao, Q., Ma, J., Li, Y., Kuang, J., Yang, X., Lu, A., Cheung, K. C. P., Melino, G. & Jia, W., Dec 2024, In: Cell Death and Differentiation. 31, 12, p. 1625-1635 11 p.

Research output: Contribution to journal › Journal article › peer-review

Gut microbiota modulation through Traditional Chinese Medicine (TCM) - improving outcomes in Gastrointestinal (GI) cancer prevention and management

Wang, Y., Zeng, Y., Chen, X., Lu, A., Jia, W. & Cheung, K. C., Dec 2024, In: Pharmacological Research - Modern Chinese Medicine. 13, 15 p., 100528.

Research output: Contribution to journal › Journal article › peer-review

Open Access

Inflammatory Processes: Key Mediators of Oncogenesis and Progression in Pancreatic Ductal Adenocarcinoma (PDAC)

Yang, L., Qiao, S., Zhang, G., Lu, A. & Li, F., 12 Oct 2024, In: International Journal of Molecular Sciences. 25, 20, 16 p., 10991.

Research output: Contribution to journal › Journal article › peer-review

Open Access

Pien Tze Huang (PZH) protects endothelial function in diabetic mice

Chen, Q., Hao, H., Guo, Z., Zuo, Y., Cheng, C. K., Zhang, C. L., Wang, L., Lu, A., Huang, Y. & He, L., 15 Jul 2024, In: Life Sciences. 349, 122723.

Research output: Contribution to journal › Journal article › peer-review

1 Citation (Scopus)

Predicting novel targets with Bayesian machine learning by integrating multiple biological signatures

Wei, X., Zhu, T., Yip, H. F., Fu, X., Jiang, D., Deng, Y., Lu, A. & Cao, D., 21 Sept 2024, In: Chemical Science. 15, 35, p. 14471-14484 14 p.

Research output: Contribution to journal › Journal article › peer-review

Open Access

Synergisitic anti-colorectal cancer effects of WNT974 combined with artesunate via cooperative regulation of p21, p27, and AKT

Gong, R. H., Chen, M., Huang, C., Wong, H. L. X., Chen, S., Bian, Z. & Chen, G. Q., Sept 2024, In: Pharmacological Research - Modern Chinese Medicine. 12, 11 p., 100498.

Research output: Contribution to journal › Journal article › peer-review

Open Access

Targeting osteoblastic 11β-HSD1 to combat high-fat diet-induced bone loss and obesity

Zhong, C., Li, N., Wang, S., Li, D., Yang, Z., Du, L., Huang, G., Li, H., Yeung, W. S., He, S., Ma, S., Wang, Z., Jiang, H., Zhang, H., Li, Z., Wen, X., Xue, S., Tao, X., Li, H. & Xie, D. & 22 others, Zhang, Y., Chen, Z., Wang, J., Yan, J., Liang, Z., Zhang, Z., Zhong, Z., Wu, Z., Wan, C., Liang, C., Wang, L., Yu, S., Ma, Y., Yu, Y., Li, F., Chen, Y., Zhang, B., Lyu, A., Ren, F., Zhou, H., Liu, J. & Zhang, G., 4 Oct 2024, In: Nature Communications. 15, 1, 18 p., 8588.

Research output: Contribution to journal › Journal article › peer-review

Open Access

The Landscape of Gut Microbiota and Its Metabolites: A Key to Understanding the Pathophysiology of Pattern in Chinese Medicine

Zhang, Z., Du, L., Ji, Q., Liu, H., Ren, Z., Ji, G., Bian, Z. X. & Zhao, L., 8 Feb 2024, In: American Journal of Chinese Medicine. 52, 1, p. 89-122 34 p.

Research output: Contribution to journal › Journal article › peer-review

Transparency and reporting characteristics of randomized controlled trials with Chinese herbal medicine formulas interventions

Wang, J., Shi, D., Wang, Y., Zhang, X., Li, H., Wang, X., Luo, S., Hu, L., Deng, J., Zhang, L., Lau, C. T., Cheng, C. W., Han, F., Li, J., Wang, P., Lyu, A., Bian, Z. & Zhang, X., Aug 2024, In: Frontiers of Medicine. 18, 4, p. 757–761 5 p.

Research output: Contribution to journal › Journal article › peer-review

Ultrasensitive detection of aggregated α-synuclein using quiescent seed amplification assay for the diagnosis of Parkinson’s disease

Mao, H., Kuang, Y., Feng, D., Chen, X., Lu, L., Xia, W., Gan, T., Huang, W., Guo, W., Yi, H., Yang, Y., Wu, Z., Dai, W., Sun, H., Wu, J., Zhang, R., Zhang, S., Lin, X., Yong, Y. & Yang, X. & 12 others, Li, H., Wu, W., Huang, X., Bian, Z., Wong, H. L. X., Wang, X. L., Poppell, M., Ren, Y., Liu, C., Zou, W. Q., Chen, S. & Xu, P. Y., 24 Jul 2024, In: Translational Neurodegeneration. 13, 1, 16 p., 35.

Research output: Contribution to journal › Journal article › peer-review

Open Access

2 Citations (Scopus)

针刺临床试验中假针刺对照报告指南与清单（SHARE）

Translated title of the contribution: Sham acupuncture reporting guidelines and a checklist in clinical trials刘晓玉, 马培宏, 刘志顺, 郭义, 周科华, 卞兆祥, 孙承颐, 刘婷兰, 熊芝怡, 谢依璇, 陆盈, 劳力行, 何丽云, 刘保延, 刘存志, 闫世艳 & SHARE Workgroup, Jul 2024, In: 中国循证医学杂志. 24, 7, p. 745-750 6 p.

Research output: Contribution to journal › Journal article › peer-review

Open Access

2023

Gut microbiota-derived ursodeoxycholic acid alleviates low birth weight-induced colonic inflammation by enhancing M2 macrophage polarization

Pi, Y., Wu, Y., Zhang, X., Lu, D., Han, D., Zhao, J., Zheng, X., Zhang, S., Ye, H., Lian, S., Bai, Y., Wang, Z., Tao, S., Ni, D., Zou, X., Jia, W., Zhang, G., Li, D. & Wang, J., 31 Jan 2023, In: Microbiome. 11, 19.

Research output: Contribution to journal › Journal article › peer-review

Open Access

47 Citations (Scopus)

2022

Comparative study between the effects of aged and fresh Chinese baijiu on gut microbiota and host metabolism

Fang, C., Lu, W., Liu, Q., Chen, Y., Jia, W. & Xu, Y., Oct 2022, In: Food Bioscience. 49, 101859.

Research output: Contribution to journal › Journal article › peer-review

5 Citations (Scopus)

Gut Microbiome-Linked Metabolites in the Pathobiology of Major Depression With or Without Anxiety—A Role for Bile Acids

MahmoudianDehkordi, S., Bhattacharyya, S., Brydges, C. R., Jia, W., Fiehn, O., Rush, A. J., Dunlop, B. W., Kaddurah-Daouk, R. & Mood Disorders Precision Medicine Consortium, 20 Jul 2022, In: Frontiers in Neuroscience. 16, 937906.

Research output: Contribution to journal › Journal article › peer-review

Open Access

32 Citations (Scopus)

Integrated network pharmacology and metabolomics to reveal the mechanism of QiShenYiQi Dripping Pills against cardiac structural and functional abnormalities

Zhang, J., Yang, Z., Jia, X., Li, X., Wang, X., Rong, H., Liang, Y., Zeng, W., Jia, W. & Ma, X., 24 Oct 2022, In: Frontiers in Pharmacology. 13, 14 p., 1017433.

Research output: Contribution to journal › Journal article › peer-review

Open Access

2 Citations (Scopus)

ReDisX, a machine learning approach, rationalizes rheumatoid arthritis and coronary artery disease patients uniquely upon identifying subpopulation differentiation markers from their genomic data

Yip, H. F., Chowdhury, D., Wang, K., Liu, Y., Gao, Y., Lan, L., Zheng, C., Guan, D., Lam, K. F., Zhu, H., Tai, X. & Lu, A., Aug 2022, In: Frontiers in Medicine. 9, 26 p.

Research output: Contribution to journal › Journal article › peer-review

Open Access

1 Citation (Scopus)

Targeted metabolomics reveals aberrant profiles of serum bile acids in patients with schizophrenia

Qing, Y., Wang, P., Cui, G., Zhang, J., Liang, K., Xia, Z., Wang, P., He, L. & Jia, W., 18 Aug 2022, In: Schizophrenia. 8, 10 p., 65.

Research output: Contribution to journal › Journal article › peer-review

Open Access

8 Citations (Scopus)

2020

基于BV2小胶质细胞极化探索片仔癀抗炎机制

Translated title of the contribution: Exploring Anti-inflammation Mechanism of Pien Tze Huang via Regulating of Microglia Polarization舒海洋, 樊丹采, 赵宁, 吕诚, 吕爱平 & 何小鹃, Mar 2020, In: 中国实验方剂学杂志. 26, 5, p. 48-53 6 p.

Research output: Contribution to journal › Journal article › peer-review

1 Citation (Scopus)

2019

《溫病條辨》濕熱病之用藥規律探討

Translated title of the contribution: Discussion on the rules of herb application for febrile diseases in the “Itemized Differentiation on Febrile Diseases”鄧曉濤, 蔡嘉傑 & 李敏, Oct 2019, In: 香港中醫雜誌. 14, 4, 6 p.

Research output: Contribution to journal › Journal article › peer-review

2016

Characterization of oxygenated metabolites of ginsenoside Rg₁ in plasma and urine of rat

Wang, J. R., Tong, T. T., Yau, L. F., Chen, C. Y., Bai, L. P., MA, J., Hu, M., LIU, L. & JIANG, Z. H., 15 Jul 2016, In: Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 1026, p. 75-86 12 p.

Research output: Contribution to journal › Journal article › peer-review

13 Citations (Scopus)

2015

Characterization of oxygenated metabolites of ginsenoside Rb₁ in plasma and urine of rat

Wang, J. R., Yau, L. F., Tong, T. T., Feng, Q. T., Bai, L. P., Ma, J., Hu, M., Liu, L. & Jiang, Z. H., 18 Mar 2015, In: Journal of Agricultural and Food Chemistry. 63, 10, p. 2689-2700 12 p.

Research output: Contribution to journal › Journal article › peer-review

12 Citations (Scopus)

The Long-Term Consumption of Ginseng Extract Reduces the Susceptibility of Intermediate-Aged Hearts to Acute Ischemia Reperfusion Injury

Luo, P., Dong, G., Liu, L. & Zhou, H., 9 Dec 2015, In: PLoS ONE. 10, 12, 18 p., e0144733.

Research output: Contribution to journal › Journal article › peer-review

Open Access

28 Citations (Scopus)

2014

Catechins and procyanidins of ginkgo biloba show potent activities towards the inhibition of β-amyloid peptide aggregation and destabilization of preformed fibrils

Xie, H., Wang, J. R., Yau, L. F., Liu, Y., Liu, L., Han, S. Q. B., Zhao, Z. & Jiang, Z. H., Apr 2014, In: Molecules. 19, 4, p. 5119-5134 16 p.

Research output: Contribution to journal › Journal article › peer-review

Open Access

File

46 Citations (Scopus)

49 Downloads (Pure)

HMGB1 is involved in autophagy inhibition caused by SNCA/alpha-synuclein overexpression: a process modulated by the natural autophagy inducer corynoxine B

Song, J.-X., Lu, J. H., Liu, L. F., Chen, L. L., DURAIRAJAN, S. S. K., Yue, Z., ZHANG, H. Q. & LI, M., 1 Jan 2014, In: Autophagy. 10, 1, p. 144-54 11 p.

Research output: Contribution to journal › Journal article › peer-review

Open Access

Improved sphingolipidomic approach based on ultra-high performance liquid chromatography and multiple mass spectrometries with application to cellular neurotoxicity

Wang, J. R., Zhang, H., Yau, L. F., Mi, J. N., Lee, S., Lee, K. C., Hu, P., Liu, L. & Jiang, Z. H., 17 Jun 2014, In: Analytical Chemistry. 86, 12, p. 5688-5696 9 p.

Research output: Contribution to journal › Journal article › peer-review

40 Citations (Scopus)

Quantitative analysis of the flavonoid glycosides and terpene trilactones in the extract of ginkgo biloba and evaluation of their inhibitory activity towards fibril formation of β-amyloid peptide

Xie, H., Wang, J. R., Yau, L. F., Liu, Y., Liu, L., Han, S. Q. B., Zhao, Z. & Jiang, Z. H., Apr 2014, In: Molecules. 19, 4, p. 4466-4478 13 p.

Research output: Contribution to journal › Journal article › peer-review

Open Access

File

51 Citations (Scopus)

42 Downloads (Pure)

Quantitative comparison and metabolite profiling of saponins in different parts of the root of panax notoginseng

Wang, J. R., Yau, L. F., Gao, W. N., Liu, Y., Yick, P. W., LIU, L. & JIANG, Z. H., 10 Sept 2014, In: Journal of Agricultural and Food Chemistry. 62, 36, p. 9024-9034 11 p.

Research output: Contribution to journal › Journal article › peer-review

Open Access

106 Citations (Scopus)

Transformation of ginsenosides from notoginseng by artificial gastric juice can increase cytotoxicity toward cancer cells

Wang, J. R., Yau, L. F., Zhang, R., Xia, Y., Ma, J., Ho, H. M., Hu, P., Hu, M., Liu, L. & Jiang, Z. H., 26 Mar 2014, In: Journal of Agricultural and Food Chemistry. 62, 12, p. 2558-2573 16 p.

Research output: Contribution to journal › Journal article › peer-review

56 Citations (Scopus)

2012

A cellular lipidomic study on the Aβ-induced neurotoxicity and neuroprotective effects of EGCG by using UPLC/MS-based glycerolipids profiling and multivariate analysis

Zhang, H., Wang, J. R., Yau, L. F., Ho, H. M., Chan, C. L., Hu, P., Liu, L. & Jiang, Z. H., Dec 2012, In: Molecular BioSystems. 8, 12, p. 3208-3215 8 p.

Research output: Contribution to journal › Journal article › peer-review

19 Citations (Scopus)

Efficacy and safety of Fufangkushen colon-coated capsule in the treatment of ulcerative colitis compared with mesalazine: A double-blinded and randomized study

Gong, Y., Zha, Q., Li, L., Liu, Y., Yang, B., LIU, L., LYU, A., Lin, Y. & Jiang, M., 1 Jun 2012, In: Journal of Ethnopharmacology. 141, 2, p. 592-598 7 p.

Research output: Contribution to journal › Journal article › peer-review

57 Citations (Scopus)

Immunosuppressive decalin derivatives from red yeast rice

Zhu, L., Lu, J. G., Li, T., Zhu, G. Y., Han, S. Q. B., Hsiao, W. W. L., Liu, L. & Jiang, Z. H., 27 Apr 2012, In: Journal of Natural Products. 75, 4, p. 567-571 5 p.

Research output: Contribution to journal › Journal article › peer-review

19 Citations (Scopus)

Paeoniflorin reduced acute toxicity of aconitine in rats is associated with the pharmacokinetic alteration of aconitine

Fan, Y. F., Xie, Y., Liu, L., Ho, H. M., Wong, Y. F., Liu, Z. Q. & Zhou, H., 1 Jun 2012, In: Journal of Ethnopharmacology. 141, 2, p. 701-708 8 p.

Research output: Contribution to journal › Journal article › peer-review

47 Citations (Scopus)

Pharmacokinetics of aconitine as the targeted marker of Fuzi (Aconitum carmichaeli) following single and multiple oral administrations of Fuzi extracts in rat by UPLC/MS/MS

Tang, L., Gong, Y., Lv, C., Ye, L., LIU, L. & Liu, Z., 1 Jun 2012, In: Journal of Ethnopharmacology. 141, 2, p. 736-741 6 p.

Research output: Contribution to journal › Journal article › peer-review

80 Citations (Scopus)

Recent developments in bone anabolic therapy for osteoporosis

Guo, B., Peng, S., Liang, C., He, X., Xiao, C., Lu, C., Jiang, M., Zhao, H., Lyu, A. & Zhang, G., Nov 2012, In: Expert Review of Endocrinology and Metabolism. 7, 6, p. 677-685 9 p.

Research output: Contribution to journal › Journal article › peer-review

6 Citations (Scopus)

Total ginsenosides of radix ginseng modulates tricarboxylic acid cycle protein expression to enhance cardiac energy metabolism in ischemic rat heart tissues

Wang, J. R., Zhou, H., Yi, X. Q., Jiang, Z. H. & Liu, L., Nov 2012, In: Molecules. 17, 11, p. 12746-12757 12 p.

Research output: Contribution to journal › Journal article › peer-review

Open Access

31 Citations (Scopus)

2011

Ginseng protects rodent hearts from acute myocardial ischemia-reperfusion injury through GR/ER-activated RISK pathway in an endothelial NOS-dependent mechanism

Zhou, H., Hou, S. Z., Luo, P., Zeng, B., Wang, J. R., Wong, Y. F., JIANG, Z. H. & LIU, L., 17 May 2011, In: Journal of Ethnopharmacology. 135, 2, p. 287-298 12 p.

Research output: Contribution to journal › Journal article › peer-review

70 Citations (Scopus)

Perspective: The clinical trial barriers

LIU, L., Leung, E. L. H. & TIAN, X. Y., 22 Dec 2011, In: Nature. 480, 7378, p. S100 1 p.

Research output: Contribution to journal › Journal article › peer-review

Open Access

26 Citations (Scopus)

Role of the interaction between puerarin and the erythrocyte membrane in puerarin-induced hemolysis

Hou, S. Z., Su, Z. R., Chen, S. X., Ye, M. R., Huang, S., LIU, L., Zhou, H. & Lai, X. P., 15 Jul 2011, In: Chemico-Biological Interactions. 192, 3, p. 184-192 9 p.

Research output: Contribution to journal › Journal article › peer-review

37 Citations (Scopus)

The in vitro structure-related anti-cancer activity of ginsenosides and their derivatives

Dong, H., Bai, L. P., Wong, V. K. W., Zhou, H., Wang, J. R., Liu, Y., Jiang, Z. H. & Liu, L., Dec 2011, In: Molecules. 16, 12, p. 10619-10630 12 p.

Research output: Contribution to journal › Journal article › peer-review

Open Access

86 Citations (Scopus)

2010

Anti-inflammatory and analgesic effect of plumbagin through inhibition of nuclear factor-κB activation

Luo, P., Wong, Y. F., Ge, L., Zhang, Z. F., Liu, Y., LIU, L. & Zhou, H., Dec 2010, In: Journal of Pharmacology and Experimental Therapeutics. 335, 3, p. 735-742 8 p.

Research output: Contribution to journal › Journal article › peer-review

101 Citations (Scopus)

Asian ginseng extract inhibits in vitro and in vivo growth of mouse lewis lung carcinoma via modulation of ERK-p53 and NF-κB signaling

Wong, V. K. W., Cheung, S. S. F., Li, T., JIANG, Z. H., Wang, J. R., Dong, H., Yi, X. Q., Zhou, H. & LIU, L., Nov 2010, In: Journal of Cellular Biochemistry. 111, 4, p. 899-910 12 p.

Research output: Contribution to journal › Journal article › peer-review

51 Citations (Scopus)

Development of liposomal salbutamol sulfate dry powder inhaler formulation

Huang, W. H., Yang, Z., Wu, H., Wong, Y. F., Zhao, Z. & Liu, L., Mar 2010, In: Biological and Pharmaceutical Bulletin. 33, 3, p. 512-517 6 p.

Research output: Contribution to journal › Journal article › peer-review

Open Access

22 Citations (Scopus)

Herbal interactions with anticancer drugs: Mechanistic and clinical considerations

Yang, A. K., He, S. M., LIU, L., Liu, J. P., Wei, M. Q. & Zhou, S. F., 2010, In: Current Medicinal Chemistry. 17, 16, p. 1635-1678 44 p.

Research output: Contribution to journal › Journal article › peer-review

81 Citations (Scopus)

Matrine induces cell anergy in human jurkat T cells through modulation of mitogen-activated protein kinases and nuclear factor of activated t-cells signaling with concomitant up-regulation of anergy-associated genes expression

Li, T., Wong, V. K. W., Yi, X. Q., Wong, Y. F., Zhou, H. & LIU, L., Jan 2010, In: Biological and Pharmaceutical Bulletin. 33, 1, p. 40-46 7 p.

Research output: Contribution to journal › Journal article › peer-review

Open Access

29 Citations (Scopus)

Total ginsenosides increase coronary perfusion flow in isolated rat hearts through activation of PI3K/Akt-eNOS signaling

Yi, X. Q., Li, T., Wang, J. R., Wong, V. K. W., Luo, P., Wong, I. Y. F., Jiang, Z. H., Liu, L. & Zhou, H., Nov 2010, In: Phytomedicine. 17, 13, p. 1006-1015 10 p.

Research output: Contribution to journal › Journal article › peer-review

39 Citations (Scopus)

口服中药治疗肺癌的作用与优势

Translated title of the contribution: Effect and advantage of orally taking Chinese herbal medicine for treatment of lung cancer田晓英 & 刘良, 1 Nov 2010, In: 中国中药杂志. 35, 21, p. 2795-2800 6 p.

Research output: Contribution to journal › Journal article › peer-review

7 Citations (Scopus)

Office of the Dean of Chinese Medicine

Research Output

Search results