Mr. & Mrs. Ko Chi Ming Centre for Parkinson's Disease Research

2025

The rheumatoid arthritis drug Auranofin targets peroxiredoxin 1 and peroxiredoxin 2 to trigger ROS-endoplasmic reticulum stress axis-mediated cell death and cytoprotective autophagy

Yang, W., Zhu, Z., Zhou, C., Chen, J., Ou, J., Tong, H., Iyaswamy, A., Chen, P., Wei, X., Yang, C., Xiao, W., Wang, J. & Zhang, W., Jun 2025, In: Free Radical Biology and Medicine. 233, p. 1-12 12 p.

Research output: Contribution to journal › Journal article › peer-review

1 Citation (Scopus)

2024

6PPD-quinone exposure induces neuronal mitochondrial dysfunction to exacerbate Lewy neurites formation induced by α-synuclein preformed fibrils seeding

Fang, J., Wang, X., Cao, G., Wang, F., Ru, Y., Wang, B., Zhang, Y., Zhang, D., Yan, J., Xu, J., Ji, J., Ji, F., Zhou, Y., Guo, L., Li, M., Liu, W., Cai, X. & Cai, Z., 5 Mar 2024, In: Journal of Hazardous Materials. 465, 133312.

Research output: Contribution to journal › Journal article › peer-review

30 Citations (Scopus)

Aspartame Causes Developmental Defects and Teratogenicity in Zebra Fish Embryo: Role of Impaired SIRT1/FOXO3a Axis in Neuron Cells

Pandaram, A., Paul, J., Wankhar, W., Thakur, A., Verma, S., Vasudevan, K., Wankhar, D., Kammala, A. K., Sharma, P., Jaganathan, R., Iyaswamy, A. & Rajan, R., Apr 2024, In: Biomedicines. 12, 4, 19 p., 855.

Research output: Contribution to journal › Journal article › peer-review

Open Access

6 Citations (Scopus)

Corynoxine promotes TFEB/TFE3-mediated autophagy and alleviates Aβ pathology in Alzheimer’s disease models

Guan, X.-J., Deng, Z.-Q., Liu, J., Su, C.-F., Tong, B. C. K., Zhu, Z., Sreenivasmurthy, S. G., Kan, Y.-X., Lu, K., Chu, C. P. K., Pi, R.-B., Cheung, K.-H., Iyaswamy, A., Song, J.-X. & Li, M., May 2024, In: Acta Pharmacologica Sinica. 45, 5, p. 900–913 14 p.

Research output: Contribution to journal › Journal article › peer-review

12 Citations (Scopus)

Discovery of plasma biomarkers for Parkinson's disease diagnoses based on metabolomics and lipidomics

Wang, X., Wang, B., Ji, F., Yan, J., Fang, J., Zhang, D., Xu, J., Ji, J., Hao, X., Luan, H., Hong, Y., Qiu, S., Li, M., Yang, Z., Liu, W., Cai, X. & Cai, Z., Nov 2024, In: Chinese Chemical Letters. 35, 11, 109653.

Research output: Contribution to journal › Journal article › peer-review

1 Citation (Scopus)

Interaction of Tau with Kinesin-1: Effect of Kinesin-1 Heavy Chain Elimination on Autophagy-Mediated Mutant Tau Degradation

Selvarasu, K., Singh, A. K., Dakshinamoorthy, A., Sreenivasmurthy, S. G., Iyaswamy, A., Radhakrishnan, M., Patnaik, S., Huang, J. D., Williams, L. L., Senapati, S. & Durairajan, S. S. K., Jan 2024, In: Biomedicines. 12, 1, 17 p., 5.

Research output: Contribution to journal › Journal article › peer-review

Open Access

4 Citations (Scopus)

Molecular engineering of a theranostic molecule that detects Aβ plaques, inhibits Iowa and Dutch mutation Aβ self-aggregation and promotes lysosomal biogenesis for Alzheimer's disease

Iyaswamy, A., Wang, X., Zhang, H., Vasudevan, K., Wankhar, D., Lu, K., Krishnamoorthi, S., Guan, X.-J., Su, C.-F., Liu, J., Kan, Y., Jaganathan, R., Deng, Z., Li, H. W., Wong, M. S. & Li, M., 21 Aug 2024, In: Journal of Materials Chemistry B. 12, 31, p. 7543-7556 14 p.

Research output: Contribution to journal › Journal article › peer-review

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2 Citations (Scopus)

24 Downloads (Pure)

Peptide-Conjugated Vascular Endothelial Extracellular Vesicles Encapsulating Vinorelbine for Lung Cancer Targeted Therapeutics

Gaurav, I., Thakur, A., Zhang, K., Thakur, S., Hu, X., Xu, Z., Kumar, G., Jaganathan, R., Iyaswamy, A., Li, M., Zhang, G. & Yang, Z., 17 Oct 2024, In: Nanomaterials. 14, 20, 22 p., 1669.

Research output: Contribution to journal › Journal article › peer-review

Open Access

Role of Candida species in pathogenesis, immune regulation, and prognostic tools for managing ulcerative colitis and Crohn's disease

Patnaik, S., Durairajan, S. S. K., Singh, A. K., Krishnamoorthi, S., Iyaswamy, A., Mandavi, S. P., Jeewon, R. & Williams, L. L., 28 Dec 2024, In: World Journal of Gastroenterology. 30, 48, p. 5212-5220 9 p.

Research output: Contribution to journal › Journal article › peer-review

Open Access

2023

Chemical mitophagy modulators: Drug development strategies and novel regulatory mechanisms

Dong, Y., Zhuang, X. X., Wang, Y. T., Tan, J., Feng, D., Li, M., Zhong, Q., Song, Z., Shen, H. M., Fang, E. F. & Lu, J. H., Aug 2023, In: Pharmacological Research. 194, 15 p., 106835.

Research output: Contribution to journal › Journal article › peer-review

Open Access

16 Citations (Scopus)

Fe65-engineered neuronal exosomes encapsulating corynoxine-B ameliorate cognition and pathology of Alzheimer’s disease

Iyaswamy, A., Thakur, A., Guan, X. J., Krishnamoorthi, S., Fung, T. Y., Lu, K., Gaurav, I., Yang, Z., Su, C.-F., Lau, K.-F., Zhang, K., Ng, R. C. L., Lian, Q., Cheung, K. H., Ye, K., Chen, H. J. & Li, M., 23 Oct 2023, In: Signal Transduction and Targeted Therapy. 8, 1, 404.

Research output: Contribution to journal › Journal article › peer-review

Open Access

40 Citations (Scopus)

Impact and Advances in the Role of Bacterial Extracellular Vesicles in Neurodegenerative Disease and Its Therapeutics

Iyaswamy, A., Lu, K., Guan, X. J., Kan, Y., Su, C., Liu, J., Jaganathan, R., Vasudevan, K., Paul, J., Thakur, A. & Li, M., Jul 2023, In: Biomedicines. 11, 7, 13 p., 2056.

Research output: Contribution to journal › Journal article › peer-review

Open Access

12 Citations (Scopus)

Real-Time Detection and Visualization of Amyloid-β Aggregates Induced by Hydrogen Peroxide in Cell and Mouse Models of Alzheimer’s Disease

Wang, X., Iyaswamy, A., Xu, D., Krishnamoorthi, S., Sreenivasmurthy, S. G., Yang, Y., Li, Y., Chen, C., Li, M., Li, H.-W. & Wong, M. S., 11 Jan 2023, In: ACS Applied Materials and Interfaces. 15, 1, p. 39–47 9 p.

Research output: Contribution to journal › Journal article › peer-review

Open Access

42 Citations (Scopus)

TNEA therapy promotes the autophagic degradation of NLRP3 inflammasome in a transgenic mouse model of Alzheimer’s disease via TFEB/TFE3 activation

Lin, W., Li, Z., Liang, G., Zhou, R., Zheng, X., Tao, R., Huo, Q., Su, C., Li, M., Xu, N., Tang, C. & Song, J. X., 2 Feb 2023, In: Journal of Neuroinflammation. 20, 1, 16 p., 21.

Research output: Contribution to journal › Journal article › peer-review

Open Access

15 Citations (Scopus)

Urine biomarkers discovery by metabolomics and machine learning for Parkinson's disease diagnoses

Wang, X., Hao, X., Yan, J., Xu, J., Hu, D., Ji, F., Zeng, T., Wang, F., Wang, B., Fang, J., Ji, J., Luan, H., Hong, Y., Zhang, Y., Chen, J., Li, M., Yang, Z., Zhang, D., Liu, W. & Cai, X. & 1 others, Cai, Z., Oct 2023, In: Chinese Chemical Letters. 34, 10, 108230.

Research output: Contribution to journal › Journal article › peer-review

11 Citations (Scopus)

2022

3-Acetylpyridine On-Tissue Paternò–Büchi Derivatization Enabling High Coverage Lipid C═C Location-Resolved MS Imaging in Biological Tissues

Chen, Y., Xie, C., Wang, X., Cao, G., Ru, Y., Song, Y., Iyaswamy, A., Li, M., Wang, J. & Cai, Z., 8 Nov 2022, In: Analytical Chemistry. 94, 44, p. 15367-15376 10 p.

Research output: Contribution to journal › Journal article › peer-review

23 Citations (Scopus)

Bromo-protopine, a novel protopine derivative, alleviates tau pathology by activating chaperone-mediated autophagy for Alzheimer’s disease therapy

Sreenivasmurthy, S. G., Iyaswamy, A., Krishnamoorthi, S., Reddi, R. N., Kammala, A. K., Vasudevan, K., Senapati, S., Zhu, Z., Su, C. F., Liu, J., Guan, X. J., Chua, K. K., Cheung, K. H., Chen, H., Zhang, H. J., Zhang, Y., Song, J. X., Kumar Durairajan, S. S. & Li, M., 26 Oct 2022, In: Frontiers in Molecular Biosciences. 9, 1030534.

Research output: Contribution to journal › Journal article › peer-review

Open Access

27 Citations (Scopus)

Celastrol Downmodulates Alpha-Synuclein-Specific T Cell Responses by Mediating Antigen Trafficking in Dendritic Cells

NG, L., WANG, X., YANG, C., SU, C., LI, M. & CHEUNG, A. K. L., 2 Mar 2022, In: Frontiers in Immunology. 13, 17 p., 833515.

Research output: Contribution to journal › Journal article › peer-review

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6 Citations (Scopus)

Celastrol enhances transcription factor EB (TFEB)-mediated autophagy and mitigates Tau pathology: Implications for Alzheimer's disease therapy

Yang, C., Su, C., Iyaswamy, A., Krishnamoorthi, S. K., Zhu, Z., Yang, S., Tong, B. C., Liu, J., Sreenivasmurthy, S. G., Guan, X., Kan, Y., Wu, A. J., Huang, A. S., Tan, J., Cheung, K., Song, J. & Li, M., Apr 2022, In: Acta Pharmaceutica Sinica B. 12, 4, p. 1707-1722 16 p.

Research output: Contribution to journal › Journal article › peer-review

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73 Citations (Scopus)

Chinese herbal medicine treatment based on subgroup differentiation as adjunct therapy for Parkinson’s disease: study protocol of a pilot add-on, randomised, controlled, pragmatic clinical trial

Yuen, S. C. S., Chua, K. K., Zhong, L. L. D., Chan, K. W., Chan, C. K. H., Chan, K. L., Lin, Z., Mok, V., Lau, A. Y. & Li, M., 24 Jan 2022, In: Chinese Medicine. 17, 1, 9 p., 16.

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1 Citation (Scopus)

118 Downloads (Pure)

Corrigendum: Celastrol Downmodulates Alpha-Synuclein-Specific T Cell Responses by Mediating Antigen Trafficking in Dendritic Cells

Ng, L., Wang, X., Yang, C., Su, C., Li, M. & Cheung, A. K. L., 20 May 2022, In: Frontiers in Immunology. 13, 1 p., 907993.

Research output: Contribution to journal › Journal article › peer-review

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5 Citations (Scopus)

Corynoxine B derivative CB6 prevents Parkinsonian toxicity in mice by inducing PIK3C3 complex-dependent autophagy

Zhu, Z., Liu, L.-F., Su, C.-F., Liu, J., Tong, B. C. K., Iyaswamy, A., Krishnamoorthi, S., Sreenivasmurthy, S. G., Guan, X.-J., Kan, Y.-X., Xie, W.-J., Zhao, C.-L., Cheung, K.-H., Lu, J.-H., Tan, J.-Q., Zhang, H.-J., Song, J.-X. & Li, M., Oct 2022, In: Acta Pharmacologica Sinica. 43, 10, p. 2511-2526 16 p.

Research output: Contribution to journal › Journal article › peer-review

21 Citations (Scopus)

Enhancing autophagy maturation with CCZ1-MON1A complex alleviates neuropathology and memory defects in Alzheimer disease models

Cai, C. Z., Zhuang, X. X., Zhu, Q., Wu, M. Y., Su, H., Wang, X. J., Iyaswamy, A., Yue, Z., Wang, Q., Zhang, B., Xue, Y., Tan, J., Li, M., He, H. & Lu, J. H., 24 Jan 2022, In: Theranostics. 12, 4, p. 1738-1755 18 p.

Research output: Contribution to journal › Journal article › peer-review

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16 Citations (Scopus)

Lysosomal TPCN (two pore segment channel) inhibition ameliorates beta-amyloid pathology and mitigates memory impairment in Alzheimer disease

Tong, B. C. K., Wu, A. J., Huang, A. S., Dong, R., Malampati, S., Iyaswamy, A., Krishnamoorthi, S., Sreenivasmurthy, S. G., Zhu, Z., Su, C., Liu, J., Song, J., Lu, J. H., Tan, J., Pan, W., Li, M. & Cheung, K. H., 4 Mar 2022, In: Autophagy. 18, 3, p. 624-642 19 p.

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35 Citations (Scopus)

38 Downloads (Pure)

Mechanistic Insights into Selective Autophagy Subtypes in Alzheimer’s Disease

Guan, X., Iyaswamy, A., Sreenivasmurthy, S. G., Su, C., Zhu, Z., Liu, J., Kan, Y., Cheung, K. H., Lu, J., Tan, J. & Li, M., Apr 2022, In: International Journal of Molecular Sciences. 23, 7, 22 p., 3609.

Research output: Contribution to journal › Journal article › peer-review

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17 Citations (Scopus)

Protopine promotes the proteasomal degradation of pathological tau in Alzheimer's disease models via HDAC6 inhibition

Sreenivasmurthy, S. G., Iyaswamy, A., Krishnamoorthi, S., Senapati, S., Malampati, S., Zhu, Z., Su, C. F., Liu, J., Guan, X. J., Tong, B. C. K., Cheung, K. H., Tan, J. Q., Lu, J. H., Durairajan, S. S. K., Song, J. X. & Li, M., Feb 2022, In: Phytomedicine. 96, 14 p., 153887.

Research output: Contribution to journal › Journal article › peer-review

41 Citations (Scopus)

Reduction of kinesin I heavy chain decreases tau hyperphosphorylation, aggregation, and memory impairment in Alzheimer’s disease and tauopathy models

Selvarasu, K., Singh, A. K., Iyaswamy, A., Sreenivasmurthy, S. G., Krishnamoorthi, S., Bera, A. K., Huang, J. D. & Durairajan, S. S. K., 25 Oct 2022, In: Frontiers in Molecular Biosciences. 9, 16 p., 1050768.

Research output: Contribution to journal › Journal article › peer-review

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21 Citations (Scopus)

Tetrandrine ameliorates cognitive deficits and mitigates tau aggregation in cell and animal models of tauopathies

Tong, B. C. K., Huang, A. S., Wu, A. J., Iyaswamy, A., Ho, O. K. Y., Kong, A. H. Y., Sreenivasmurthy, S. G., Zhu, Z., Su, C., Liu, J., Song, J., Li, M. & Cheung, K. H., 22 Oct 2022, In: Journal of Biomedical Science. 29, 19 p., 85.

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34 Citations (Scopus)

29 Downloads (Pure)

TFEB, a master regulator of autophagy and biogenesis, unexpectedly promotes apoptosis in response to the cyclopentenone prostaglandin 15d-PGJ2

Yang, C. B., Liu, J., Tong, B. C. K., Wang, Z. Y., Zhu, Z., Su, C. F., Sreenivasmurthy, S. G., Wu, J. X., Iyaswamy, A., Krishnamoorthi, S., Huang, S. Y., Cheung, K. H., Song, J. X., Tan, J. Q., Lu, J. H. & Li, M., May 2022, In: Acta Pharmacologica Sinica. 43, 5, p. 1251–1263 13 p.

Research output: Contribution to journal › Journal article › peer-review

20 Citations (Scopus)

Theranostic F-SLOH mitigates Alzheimer's disease pathology involving TFEB and ameliorates cognitive functions in Alzheimer's disease models

Iyaswamy, A., Wang, X., Krishnamoorthi, S., Kaliamoorthy, V., Sreenivasmurthy, S. G., Kumar Durairajan, S. S., Song, J.-X., Tong, B. C. K., Zhu, Z., Su, C.-F., Liu, J., Cheung, K.-H., Lu, J.-H., Tan, J.-Q., Li, H. W., Wong, M. S. & Li, M., May 2022, In: Redox Biology. 51, 21 p., 102280.

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58 Citations (Scopus)

32 Downloads (Pure)

Toosendanin, a late-stage autophagy inhibitor, sensitizes triple-negative breast cancer to irinotecan chemotherapy

Zhang, S., Dong, Y., Chen, X., Tan, C. S. H., Li, M., Miao, K. & Lu, J. H., 6 May 2022, In: Chinese Medicine. 17, 1, 14 p., 55.

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15 Citations (Scopus)

Toosendanin, a novel potent vacuolar-type H⁺-translocating ATPase inhibitor, sensitizes cancer cells to chemotherapy by blocking protective autophagy

Dong, Y., Zhu, G., Wang, S. F., Keon, K. A., Rubinstein, J. L., Zeng, S. X., Zhang, S., Chen, Q. L., Fu, J., Li, M., Shen, H. M., Lu, J. J., Chen, X. P. & Lu, J. H., Mar 2022, In: International Journal of Biological Sciences. 18, 7, p. 2684-2702 19 p.

Research output: Contribution to journal › Journal article › peer-review

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19 Citations (Scopus)

2021

Amyloid-β oligomer targeted theranostic probes for in vivo NIR imaging and inhibition of self-aggregation and amyloid-β induced ROS generation

Wang, X., Wang, C., Chan, H. N., Ashok, I., Krishnamoorthi, S. K., Li, M., Li, H. W. & Wong, R. M. S., 1 Mar 2021, In: Talanta. 224, 121830.

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44 Citations (Scopus)

66 Downloads (Pure)

Chronic oral administration of adipoRon reverses cognitive impairments and ameliorates neuropathology in an Alzheimer’s disease mouse model

Ng, R. C. L., Jian, M., Ma, O. K. F., Bunting, M., Kwan, J. S. C., Zhou, G. J., Krishnamoorthi, S., Iyaswamy, A., Chan, P. K., Li, M., Leung, K. M. Y., Durairajan, S. S. K., Lam, K. S. L., Chu, L. W., Festenstein, R., Chung, S. K. & Chan, K. H., Oct 2021, In: Molecular Psychiatry. 26, 10, p. 5669–5689 21 p.

Research output: Contribution to journal › Journal article › peer-review

60 Citations (Scopus)

Corynoxine Protects Dopaminergic Neurons Through Inducing Autophagy and Diminishing Neuroinflammation in Rotenone-Induced Animal Models of Parkinson’s Disease

Chen, L., Huang, Y., Yu, X., Lu, J., Jia, W., Song, J., Liu, L., Wang, Y., Huang, Y., Xie, J. & Li, M., 13 Apr 2021, In: Frontiers in Pharmacology. 12, 642900.

Research output: Contribution to journal › Journal article › peer-review

Open Access

77 Citations (Scopus)

Electroacupuncture ameliorates beta-amyloid pathology and cognitive impairment in Alzheimer disease via a novel mechanism involving activation of TFEB (transcription factor EB)

Zheng, X., Lin, W., Jiang, Y., Lu, K., Wei, W., Huo, Q., Cui, S., Yang, X., Li, M., Xu, N., Tang, C. & Song, J. X., 2 Nov 2021, In: Autophagy. 17, 11, p. 3833-3847 15 p.

Research output: Contribution to journal › Journal article › peer-review

104 Citations (Scopus)

NRBF2 is a RAB7 effector required for autophagosome maturation and mediates the association of APP-CTFs with active form of RAB7 for degradation

Cai, C. Z., Yang, C., Zhuang, X. X., Yuan, N. N., Wu, M. Y., Tan, J. Q., Song, J. X., Cheung, K. H., Su, H., Wang, Y. T., Tang, B. S., Behrends, C., Durairajan, S. S. K., Yue, Z., Li, M. & Lu, J. H., 4 May 2021, In: Autophagy. 17, 5, p. 1112-1130 19 p.

Research output: Contribution to journal › Journal article › peer-review

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39 Citations (Scopus)

Qingyangshen mitigates amyloid-β and Tau aggregate defects involving PPARα-TFEB activation in transgenic mice of Alzheimer's disease

Iyaswamy, A., Krishnamoorthi, S. K., Zhang, H., SREENIVASA MURTHY, S. G. S., Zhu, Z., Liu, J., Su, C. F., Guan, X. J., Wang, Z. Y., Cheung, K. H., Song, J., Durairajan, S. S. K. & Li, M., Oct 2021, In: Phytomedicine. 91, 153648.

Research output: Contribution to journal › Journal article › peer-review

40 Citations (Scopus)

2020

6-OH-BDE-47 exposure-induced Parkinson's disease pathology in Sprague Dawley rat

Ji, F., Zhu, Z., Zhang, M., Zhang, H., Zhu, L., Cai, X., Liu, W., Song, J., Li, M. & Cai, Z., 1 Apr 2020, In: Science of the Total Environment. 711, 135184.

Research output: Contribution to journal › Journal article › peer-review

11 Citations (Scopus)

A curcumin derivative activates TFEB and protects against parkinsonian neurotoxicity in vitro

Wang, Z., Yang, C., Liu, J., Tong, C. K. B., Zhu, Z., Malampati, S., Sreenivasmurthy, S. G., Cheung, K. H., Iyaswamy, A., Su, C., Lu, J., Song, J. & Li, M., 2 Feb 2020, In: International Journal of Molecular Sciences. 21, 4, 1515.

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42 Citations (Scopus)

23 Downloads (Pure)

A Self-Assembled α-Synuclein Nanoscavenger for Parkinson's Disease

Liu, J., Liu, C., Zhang, J., Zhang, Y., Liu, K., Song, J. X., Sreenivasmurthy, S. G., Wang, Z., Shi, Y., Chu, C., Zhang, Y., Wu, C., Deng, X., Liu, X., Song, J., Zhuang, R., Huang, S., Zhang, P., Li, M. & Wen, L. & 2 others, Zhang, Y. W. & Liu, G., 25 Feb 2020, In: ACS Nano. 14, 2, p. 1533-1549 17 p.

Research output: Contribution to journal › Journal article › peer-review

80 Citations (Scopus)

A small molecule transcription factor EB activator ameliorates beta-amyloid precursor protein and Tau pathology in Alzheimer's disease models

Song, J. X., Malampati, S., Zeng, Y., Durairajan, S. S. K., Yang, C., Tong, C. K. B., Iyaswamy, A., Shang, W. B., Sreenivasmurthy, S. G., Zhu, Z., Cheung, K. H., Lu, J. H., Tang, C., Xu, N. & Li, M., Feb 2020, In: Aging Cell. 19, 2, e13069.

Research output: Contribution to journal › Journal article › peer-review

Open Access

126 Citations (Scopus)

A stress response p38 MAP kinase inhibitor SB202190 promoted TFEB/TFE3-dependent autophagy and lysosomal biogenesis independent of p38

Yang, C., Zhu, Z., Tong, C. K. B., Iyaswamy, A., Xie, W. J., Zhu, Y., Sreenivasmurthy, S. G., Senthilkumar, K., Cheung, K. H., Song, J. X., Zhang, H. & Li, M., May 2020, In: Redox Biology. 32, 101445.

Research output: Contribution to journal › Journal article › peer-review

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42 Citations (Scopus)

NeuroDefend, a novel Chinese medicine, attenuates amyloid-β and tau pathology in experimental Alzheimer's disease models

Iyaswamy, A., Krishnamoorthi, S. K., Song, J. X., Yang, C. B., Kaliyamoorthy, V., Zhang, H., Sreenivasmurthy, S. G., Malampati, S., Wang, Z. Y., Zhu, Z., Tong, B. C. K., Cheung, K. H., Lu, J. H., Durairajan, S. S. K. & Li, M., Jan 2020, In: Journal of Food and Drug Analysis. 28, 1, p. 132-146 15 p.

Research output: Contribution to journal › Journal article › peer-review

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32 Citations (Scopus)

Pharmacological enhancement of TFEB-mediated autophagy alleviated neuronal death in oxidative stress-induced Parkinson’s disease models

Zhuang, X. X., Wang, S. F., Tan, Y., Song, J. X., Zhu, Z., Wang, Z. Y., Wu, M. Y., Cai, C. Z., Huang, Z. J., Tan, J. Q., Su, H. X., Li, M. & Lu, J. H., 18 Feb 2020, In: Cell Death and Disease. 11, 2, 18 p., 128.

Research output: Contribution to journal › Journal article › peer-review

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95 Citations (Scopus)

The Effect of Conduction Exercise and Self-Acupressure in Treatment of Parkinson's Disease: A Pilot Study

Yuen, C. S., Chua, K. K., Lau, W. H., Zhuang, Z. Y., Chow, H. Y. & Li, M., 11 Aug 2020, In: Evidence-based Complementary and Alternative Medicine. 2020, 9 p., 7950131.

Research output: Contribution to journal › Journal article › peer-review

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6 Citations (Scopus)

The Effect of Conduction Exercise and Self-Acupressure in Treatment of Parkinson’s Disease: A Pilot Study

Yuen, C. S., Chua, K. K., Lau, W. H., Zhuang, Z. Y., Chow, H. Y. & Li, M., 11 Aug 2020, In: Evidence-based Complementary and Alternative Medicine. 2020, 9 p., 7950131.

Research output: Contribution to journal › Journal article › peer-review

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Yuan-Hu Zhi Tong Prescription Mitigates Tau Pathology and Alleviates Memory Deficiency in the Preclinical Models of Alzheimer’s Disease

Iyaswamy, A., Krishnamoorthi, S. K., Liu, Y. W., Song, J., Kammala, A. K., Sreenivasmurthy, S. G., Malampati, S., Tong, C. K. B., Selvarasu, K., Cheung, K. H., Lu, J., Tan, J., Huang, C.-Y., Durairajan, S. S. K. & Li, M., 30 Oct 2020, In: Frontiers in Pharmacology. 11, 584770.

Research output: Contribution to journal › Journal article › peer-review

Open Access

26 Citations (Scopus)

2019

A Biocompatible Free Radical Nanogenerator with Real-Time Monitoring Capability for High Performance Sequential Hypoxic Tumor Therapy

Wan, Y., Lu, G., Zhang, J., Wang, Z., Li, X., Chen, R., Cui, X., Huang, Z., Xiao, Y., Chelora, J., Zhang, W., Liu, Y., Li, M., Xie, H. Y. & Lee, C. S., 1 Sept 2019, In: Advanced Functional Materials. 29, 39, 1903436.

Research output: Contribution to journal › Journal article › peer-review

113 Citations (Scopus)

Antidiabetic activity and potential mechanism of amentoflavone in diabetic mice

Su, C., Yang, C., Gong, M., Ke, Y., Yuan, P., Wang, X., Li, M., Zheng, X. & Feng, W., 11 Jun 2019, In: Molecules. 24, 11, 2184.

Research output: Contribution to journal › Journal article › peer-review

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43 Citations (Scopus)

Mr. & Mrs. Ko Chi Ming Centre for Parkinson's Disease Research

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