Mr. & Mrs. Ko Chi Ming Centre for Parkinson's Disease Research

2024

6PPD-quinone exposure induces neuronal mitochondrial dysfunction to exacerbate Lewy neurites formation induced by α-synuclein preformed fibrils seeding

Fang, J., Wang, X., Cao, G., Wang, F., Ru, Y., Wang, B., Zhang, Y., Zhang, D., Yan, J., Xu, J., Ji, J., Ji, F., Zhou, Y., Guo, L., Li, M., Liu, W., Cai, X. & Cai, Z., 5 Mar 2024, In: Journal of Hazardous Materials. 465, 133312.

Research output: Contribution to journal › Journal article › peer-review

13 Citations (Scopus)

Aspartame Causes Developmental Defects and Teratogenicity in Zebra Fish Embryo: Role of Impaired SIRT1/FOXO3a Axis in Neuron Cells

Pandaram, A., Paul, J., Wankhar, W., Thakur, A., Verma, S., Vasudevan, K., Wankhar, D., Kammala, A. K., Sharma, P., Jaganathan, R., Iyaswamy, A. & Rajan, R., Apr 2024, In: Biomedicines. 12, 4, 19 p., 855.

Research output: Contribution to journal › Journal article › peer-review

Open Access

3 Citations (Scopus)

Corynoxine promotes TFEB/TFE3-mediated autophagy and alleviates Aβ pathology in Alzheimer’s disease models

Guan, X., Deng, Z., Liu, J., Su, C., Tong, B. C. K., Zhu, Z., Sreenivasmurthy, S. G., Kan, Y., Lu, K., Chu, C. P. K., Pi, R., Cheung, K., Iyaswamy, A., Song, J. & Li, M., May 2024, In: Acta Pharmacologica Sinica. 45, 5, p. 900–913 14 p.

Research output: Contribution to journal › Journal article › peer-review

6 Citations (Scopus)

Discovery of plasma biomarkers for Parkinson's disease diagnoses based on metabolomics and lipidomics

Wang, X., Wang, B., Ji, F., Yan, J., Fang, J., Zhang, D., Xu, J., Ji, J., Hao, X., Luan, H., Hong, Y., Qiu, S., Li, M., Yang, Z., Liu, W., Cai, X. & Cai, Z., Nov 2024, In: Chinese Chemical Letters. 35, 11, 109653.

Research output: Contribution to journal › Journal article › peer-review

Interaction of Tau with Kinesin-1: Effect of Kinesin-1 Heavy Chain Elimination on Autophagy-Mediated Mutant Tau Degradation

Selvarasu, K., Singh, A. K., Dakshinamoorthy, A., Sreenivasmurthy, S. G., Iyaswamy, A., Radhakrishnan, M., Patnaik, S., Huang, J. D., Williams, L. L., Senapati, S. & Durairajan, S. S. K., Jan 2024, In: Biomedicines. 12, 1, 17 p., 5.

Research output: Contribution to journal › Journal article › peer-review

Open Access

1 Citation (Scopus)

Molecular engineering of a theranostic molecule that detects Aβ plaques, inhibits Iowa and Dutch mutation Aβ self-aggregation and promotes lysosomal biogenesis for Alzheimer's disease

Iyaswamy, A., Wang, X., Zhang, H., Vasudevan, K., Wankhar, D., Lu, K., Krishnamoorthi, S., Guan, X-J., Su, C-F., Liu, J., Kan, Y., Jaganathan, R., Deng, Z., Li, H. W., Wong, M. S. & Li, M., 21 Aug 2024, In: Journal of Materials Chemistry B. 12, 31, p. 7543-7556 14 p.

Research output: Contribution to journal › Journal article › peer-review

Open Access

File

9 Downloads (Pure)

2023

Editorial: Advances in Alzheimer’s disease diagnostics, brain delivery systems, and therapeutics

Iyaswamy, A., Vasudevan, K., Jayaraman, S., Jaganathan, R., Thakur, A., Chang, R. C. C. & Yang, C., 17 Mar 2023, In: Frontiers in Molecular Biosciences. 10, 3 p., 1162879.

Research output: Contribution to journal › Editorial

Open Access

3 Citations (Scopus)

Editorial: Autophagy in diseases—From basic to clinic

Yang, J., Ni, Z., Pi, H., Bohnert, A. & Deng, Z., 4 Jan 2023, In: Frontiers in Physiology. 13, 3 p., 1115511.

Research output: Contribution to journal › Editorial

Open Access

Fe65-engineered neuronal exosomes encapsulating corynoxine-B ameliorate cognition and pathology of Alzheimer’s disease

Iyaswamy, A., Thakur, A., Guan, X. J., Krishnamoorthi, S., Fung, T. Y., Lu, K., Gaurav, I., Yang, Z., Su, C-F., Lau, K-F., Zhang, K., Ng, R. C. L., Lian, Q., Cheung, K. H., Ye, K., Chen, H. J. & Li, M., 23 Oct 2023, In: Signal Transduction and Targeted Therapy. 8, 1, 404.

Research output: Contribution to journal › Journal article › peer-review

Open Access

21 Citations (Scopus)

Impact and Advances in the Role of Bacterial Extracellular Vesicles in Neurodegenerative Disease and Its Therapeutics

Iyaswamy, A., Lu, K., Guan, X. J., Kan, Y., Su, C., Liu, J., Jaganathan, R., Vasudevan, K., Paul, J., Thakur, A. & Li, M., Jul 2023, In: Biomedicines. 11, 7, 13 p., 2056.

Research output: Contribution to journal › Journal article › peer-review

Open Access

10 Citations (Scopus)

Real-Time Detection and Visualization of Amyloid-β Aggregates Induced by Hydrogen Peroxide in Cell and Mouse Models of Alzheimer’s Disease

Wang, X., Iyaswamy, A., Xu, D., Krishnamoorthi, S., Sreenivasmurthy, S. G., Yang, Y., Li, Y., Chen, C., Li, M., Li, H-W. & Wong, M. S., 11 Jan 2023, In: ACS Applied Materials and Interfaces. 15, 1, p. 39–47 9 p.

Research output: Contribution to journal › Journal article › peer-review

Open Access

38 Citations (Scopus)

Urine biomarkers discovery by metabolomics and machine learning for Parkinson's disease diagnoses

Wang, X., Hao, X., Yan, J., Xu, J., Hu, D., Ji, F., Zeng, T., Wang, F., Wang, B., Fang, J., Ji, J., Luan, H., Hong, Y., Zhang, Y., Chen, J., Li, M., Yang, Z., Zhang, D., Liu, W., Cai, X., & 1 othersCai, Z., Oct 2023, In: Chinese Chemical Letters. 34, 10, 108230.

Research output: Contribution to journal › Journal article › peer-review

5 Citations (Scopus)

2022

3-Acetylpyridine On-Tissue Paternò–Büchi Derivatization Enabling High Coverage Lipid C═C Location-Resolved MS Imaging in Biological Tissues

Chen, Y., Xie, C., Wang, X., Cao, G., Ru, Y., Song, Y., Iyaswamy, A., Li, M., Wang, J. & Cai, Z., 8 Nov 2022, In: Analytical Chemistry. 94, 44, p. 15367-15376 10 p.

Research output: Contribution to journal › Journal article › peer-review

18 Citations (Scopus)

Alzheimer's Disease and other Tauopathies: Exploring Efficacy of Medicinal Plant-Derived Compounds in Alleviating Tau-Mediated Neurodegeneration

Durairajan, S. S. K., Selvarasu, K., Bera, M. R., Rajaram, K., Iyaswamy, A. & Li, M., Apr 2022, In: Current Molecular Pharmacology. 15, 2, p. 361-379 19 p.

Research output: Contribution to journal › Review article › peer-review

17 Citations (Scopus)

Bromo-protopine, a novel protopine derivative, alleviates tau pathology by activating chaperone-mediated autophagy for Alzheimer’s disease therapy

Sreenivasmurthy, S. G., Iyaswamy, A., Krishnamoorthi, S., Reddi, R. N., Kammala, A. K., Vasudevan, K., Senapati, S., Zhu, Z., Su, C. F., Liu, J., Guan, X. J., Chua, K. K., Cheung, K. H., Chen, H., Zhang, H. J., Zhang, Y., Song, J. X., Kumar Durairajan, S. S. & Li, M., 26 Oct 2022, In: Frontiers in Molecular Biosciences. 9, 1030534.

Research output: Contribution to journal › Journal article › peer-review

Open Access

23 Citations (Scopus)

Celastrol Downmodulates Alpha-Synuclein-Specific T Cell Responses by Mediating Antigen Trafficking in Dendritic Cells

NG, L., WANG, X., YANG, C., SU, C., LI, M. & CHEUNG, A. K. L., 2 Mar 2022, In: Frontiers in Immunology. 13, 17 p., 833515.

Research output: Contribution to journal › Journal article › peer-review

Open Access

4 Citations (Scopus)

Celastrol enhances transcription factor EB (TFEB)-mediated autophagy and mitigates Tau pathology: Implications for Alzheimer's disease therapy

Yang, C., Su, C., Iyaswamy, A., Krishnamoorthi, S. K., Zhu, Z., Yang, S., Tong, B. C., Liu, J., Sreenivasmurthy, S. G., Guan, X., Kan, Y., Wu, A. J., Huang, A. S., Tan, J., Cheung, K., Song, J. & Li, M., Apr 2022, In: Acta Pharmaceutica Sinica B. 12, 4, p. 1707-1722 16 p.

Research output: Contribution to journal › Journal article › peer-review

Open Access

61 Citations (Scopus)

Chinese herbal medicine treatment based on subgroup differentiation as adjunct therapy for Parkinson’s disease: study protocol of a pilot add-on, randomised, controlled, pragmatic clinical trial

Yuen, S. C. S., Chua, K. K., Zhong, L. L. D., Chan, K. W., Chan, C. K. H., Chan, K. L., Lin, Z., Mok, V., Lau, A. Y. & Li, M., 24 Jan 2022, In: Chinese Medicine. 17, 1, 9 p., 16.

Research output: Contribution to journal › Journal article › peer-review

Open Access

File

1 Citation (Scopus)

96 Downloads (Pure)

Corrigendum: Celastrol Downmodulates Alpha-Synuclein-Specific T Cell Responses by Mediating Antigen Trafficking in Dendritic Cells

Ng, L., Wang, X., Yang, C., Su, C., Li, M. & Cheung, A. K. L., 20 May 2022, In: Frontiers in Immunology. 13, 1 p., 907993.

Research output: Contribution to journal › Journal article › peer-review

Open Access

4 Citations (Scopus)

Corynoxine B derivative CB6 prevents Parkinsonian toxicity in mice by inducing PIK3C3 complex-dependent autophagy

Zhu, Z., Liu, L., Su, C., Liu, J., Tong, B. C. K., Iyaswamy, A., Krishnamoorthi, S., Sreenivasmurthy, S. G., Guan, X., Kan, Y., Xie, W., Zhao, C., Cheung, K., Lu, J., Tan, J., Zhang, H., Song, J. & Li, M., Oct 2022, In: Acta Pharmacologica Sinica. 43, 10, p. 2511-2526 16 p.

Research output: Contribution to journal › Journal article › peer-review

20 Citations (Scopus)

Editorial: Assessing the Pharmacological Effects and Therapeutic Potential of Traditional Chinese Medicine in Neurological Disease Models: An Update

Deng, Z., Kan, Y., Li, M., Song, J. & Lu, J. H., 27 Apr 2022, In: Frontiers in Pharmacology. 13, 909153.

Research output: Contribution to journal › Editorial

Open Access

2 Citations (Scopus)

Enhancing autophagy maturation with CCZ1-MON1A complex alleviates neuropathology and memory defects in Alzheimer disease models

Cai, C. Z., Zhuang, X. X., Zhu, Q., Wu, M. Y., Su, H., Wang, X. J., Iyaswamy, A., Yue, Z., Wang, Q., Zhang, B., Xue, Y., Tan, J., Li, M., He, H. & Lu, J. H., 24 Jan 2022, In: Theranostics. 12, 4, p. 1738-1755 18 p.

Research output: Contribution to journal › Journal article › peer-review

Open Access

15 Citations (Scopus)

Klotho an Autophagy Stimulator as a Potential Therapeutic Target for Alzheimer’s Disease: A Review

Fung, T. Y., Iyaswamy, A., Sreenivasmurthy, S. G., Krishnamoorthi, S., Guan, X. J., Zhu, Z., Su, C. F., Liu, J., Kan, Y., Zhang, Y., Wong, H. L. X. & Li, M., 18 Mar 2022, In: Biomedicines. 10, 3, 705.

Research output: Contribution to journal › Review article › peer-review

Open Access

18 Citations (Scopus)

Lysosomal TPCN (two pore segment channel) inhibition ameliorates beta-amyloid pathology and mitigates memory impairment in Alzheimer disease

Tong, B. C. K., Wu, A. J., Huang, A. S., Dong, R., Malampati, S., Iyaswamy, A., Krishnamoorthi, S., Sreenivasmurthy, S. G., Zhu, Z., Su, C., Liu, J., Song, J., Lu, J. H., Tan, J., Pan, W., Li, M. & Cheung, K. H., 4 Mar 2022, In: Autophagy. 18, 3, p. 624-642 19 p.

Research output: Contribution to journal › Journal article › peer-review

Open Access

File

29 Citations (Scopus)

30 Downloads (Pure)

Mechanistic Insights into Selective Autophagy Subtypes in Alzheimer’s Disease

Guan, X., Iyaswamy, A., Sreenivasmurthy, S. G., Su, C., Zhu, Z., Liu, J., Kan, Y., Cheung, K. H., Lu, J., Tan, J. & Li, M., Apr 2022, In: International Journal of Molecular Sciences. 23, 7, 22 p., 3609.

Research output: Contribution to journal › Journal article › peer-review

Open Access

14 Citations (Scopus)

Pleiotropic effects of DCLK1 in cancer and cancer stem cells

Chhetri, D., Vengadassalapathy, S., Venkadassalapathy, S., Balachandran, V., Umapathy, V. R., Veeraraghavan, V. P., Jayaraman, S., Patil, S., Iyaswamy, A., Palaniyandi, K. & Gnanasampanthapandian, D., 26 Sept 2022, In: Frontiers in Molecular Biosciences. 9, 25 p., 965730.

Research output: Contribution to journal › Review article › peer-review

Open Access

13 Citations (Scopus)

Protopine promotes the proteasomal degradation of pathological tau in Alzheimer's disease models via HDAC6 inhibition

Sreenivasmurthy, S. G., Iyaswamy, A., Krishnamoorthi, S., Senapati, S., Malampati, S., Zhu, Z., Su, C. F., Liu, J., Guan, X. J., Tong, B. C. K., Cheung, K. H., Tan, J. Q., Lu, J. H., Durairajan, S. S. K., Song, J. X. & Li, M., Feb 2022, In: Phytomedicine. 96, 14 p., 153887.

Research output: Contribution to journal › Journal article › peer-review

33 Citations (Scopus)

Reduction of kinesin I heavy chain decreases tau hyperphosphorylation, aggregation, and memory impairment in Alzheimer’s disease and tauopathy models

Selvarasu, K., Singh, A. K., Iyaswamy, A., Sreenivasmurthy, S. G., Krishnamoorthi, S., Bera, A. K., Huang, J. D. & Durairajan, S. S. K., 25 Oct 2022, In: Frontiers in Molecular Biosciences. 9, 16 p., 1050768.

Research output: Contribution to journal › Journal article › peer-review

Open Access

17 Citations (Scopus)

Tetrandrine ameliorates cognitive deficits and mitigates tau aggregation in cell and animal models of tauopathies

Tong, B. C. K., Huang, A. S., Wu, A. J., Iyaswamy, A., Ho, O. K. Y., Kong, A. H. Y., Sreenivasmurthy, S. G., Zhu, Z., Su, C., Liu, J., Song, J., Li, M. & Cheung, K. H., 22 Oct 2022, In: Journal of Biomedical Science. 29, 19 p., 85.

Research output: Contribution to journal › Journal article › peer-review

Open Access

File

23 Citations (Scopus)

30 Downloads (Pure)

TFEB, a master regulator of autophagy and biogenesis, unexpectedly promotes apoptosis in response to the cyclopentenone prostaglandin 15d-PGJ2

Yang, C. B., Liu, J., Tong, B. C. K., Wang, Z. Y., Zhu, Z., Su, C. F., Sreenivasmurthy, S. G., Wu, J. X., Iyaswamy, A., Krishnamoorthi, S., Huang, S. Y., Cheung, K. H., Song, J. X., Tan, J. Q., Lu, J. H. & Li, M., May 2022, In: Acta Pharmacologica Sinica. 43, 5, p. 1251–1263 13 p.

Research output: Contribution to journal › Journal article › peer-review

19 Citations (Scopus)

Theranostic F-SLOH mitigates Alzheimer's disease pathology involving TFEB and ameliorates cognitive functions in Alzheimer's disease models

Iyaswamy, A., Wang, X., Krishnamoorthi, S., Kaliamoorthy, V., Sreenivasmurthy, S. G., Kumar Durairajan, S. S., Song, J-X., Tong, B. C. K., Zhu, Z., Su, C-F., Liu, J., Cheung, K-H., Lu, J-H., Tan, J-Q., Li, H. W., Wong, M. S. & Li, M., May 2022, In: Redox Biology. 51, 21 p., 102280.

Research output: Contribution to journal › Journal article › peer-review

Open Access

File

49 Citations (Scopus)

35 Downloads (Pure)

Toosendanin, a late-stage autophagy inhibitor, sensitizes triple-negative breast cancer to irinotecan chemotherapy

Zhang, S., Dong, Y., Chen, X., Tan, C. S. H., Li, M., Miao, K. & Lu, J. H., 6 May 2022, In: Chinese Medicine. 17, 1, 14 p., 55.

Research output: Contribution to journal › Journal article › peer-review

Open Access

11 Citations (Scopus)

Toosendanin, a novel potent vacuolar-type H⁺-translocating ATPase inhibitor, sensitizes cancer cells to chemotherapy by blocking protective autophagy

Dong, Y., Zhu, G., Wang, S. F., Keon, K. A., Rubinstein, J. L., Zeng, S. X., Zhang, S., Chen, Q. L., Fu, J., Li, M., Shen, H. M., Lu, J. J., Chen, X. P. & Lu, J. H., Mar 2022, In: International Journal of Biological Sciences. 18, 7, p. 2684-2702 19 p.

Research output: Contribution to journal › Journal article › peer-review

Open Access

17 Citations (Scopus)

2021

Amyloid-β oligomer targeted theranostic probes for in vivo NIR imaging and inhibition of self-aggregation and amyloid-β induced ROS generation

Wang, X., Wang, C., Chan, H. N., Ashok, I., Krishnamoorthi, S. K., Li, M., Li, H. W. & Wong, R. M. S., 1 Mar 2021, In: Talanta. 224, 121830.

Research output: Contribution to journal › Journal article › peer-review

Open Access

File

41 Citations (Scopus)

63 Downloads (Pure)

Chronic oral administration of adipoRon reverses cognitive impairments and ameliorates neuropathology in an Alzheimer’s disease mouse model

Ng, R. C. L., Jian, M., Ma, O. K. F., Bunting, M., Kwan, J. S. C., Zhou, G. J., Krishnamoorthi, S., Iyaswamy, A., Chan, P. K., Li, M., Leung, K. M. Y., Durairajan, S. S. K., Lam, K. S. L., Chu, L. W., Festenstein, R., Chung, S. K. & Chan, K. H., Oct 2021, In: Molecular Psychiatry. 26, 10, p. 5669–5689 21 p.

Research output: Contribution to journal › Journal article › peer-review

50 Citations (Scopus)

Corynoxine Protects Dopaminergic Neurons Through Inducing Autophagy and Diminishing Neuroinflammation in Rotenone-Induced Animal Models of Parkinson’s Disease

Chen, L., Huang, Y., Yu, X., Lu, J., Jia, W., Song, J., Liu, L., Wang, Y., Huang, Y., Xie, J. & Li, M., 13 Apr 2021, In: Frontiers in Pharmacology. 12, 642900.

Research output: Contribution to journal › Journal article › peer-review

Open Access

76 Citations (Scopus)

Electroacupuncture ameliorates beta-amyloid pathology and cognitive impairment in Alzheimer disease via a novel mechanism involving activation of TFEB (transcription factor EB)

Zheng, X., Lin, W., Jiang, Y., Lu, K., Wei, W., Huo, Q., Cui, S., Yang, X., Li, M., Xu, N., Tang, C. & Song, J. X., 2 Nov 2021, In: Autophagy. 17, 11, p. 3833-3847 15 p.

Research output: Contribution to journal › Journal article › peer-review

83 Citations (Scopus)

Factors affecting extracellular vesicles based drug delivery systems

Gaurav, I., Thakur, A., Iyaswamy, A., Wang, X., Chen, X. & Yang, Z., 2 Mar 2021, In: Molecules. 26, 6, 19 p., 1544.

Research output: Contribution to journal › Review article › peer-review

Open Access

51 Citations (Scopus)

NRBF2 is a RAB7 effector required for autophagosome maturation and mediates the association of APP-CTFs with active form of RAB7 for degradation

Cai, C. Z., Yang, C., Zhuang, X. X., Yuan, N. N., Wu, M. Y., Tan, J. Q., Song, J. X., Cheung, K. H., Su, H., Wang, Y. T., Tang, B. S., Behrends, C., Durairajan, S. S. K., Yue, Z., Li, M. & Lu, J. H., 4 May 2021, In: Autophagy. 17, 5, p. 1112-1130 19 p.

Research output: Contribution to journal › Journal article › peer-review

Open Access

31 Citations (Scopus)

Peptide-conjugated nano delivery systems for therapy and diagnosis of cancer

Gaurav, I., Wang, X., Thakur, A., Iyaswamy, A., Thakur, S., Chen, X., Kumar, G., Li, M. & Yang, Z., Sept 2021, In: Pharmaceutics. 13, 9, 1433.

Research output: Contribution to journal › Review article › peer-review

Open Access

24 Citations (Scopus)

Qingyangshen mitigates amyloid-β and Tau aggregate defects involving PPARα-TFEB activation in transgenic mice of Alzheimer's disease

Iyaswamy, A., Krishnamoorthi, S. K., Zhang, H., SREENIVASA MURTHY, S. G. S., Zhu, Z., Liu, J., Su, C. F., Guan, X. J., Wang, Z. Y., Cheung, K. H., Song, J., Durairajan, S. S. K. & Li, M., Oct 2021, In: Phytomedicine. 91, 153648.

Research output: Contribution to journal › Journal article › peer-review

36 Citations (Scopus)

Resveratrol in Rodent Models of Parkinson’s Disease: A Systematic Review of Experimental Studies

Su, C. F., Jiang, L., Zhang, X-W., Iyaswamy, A. & Li, M., 22 Apr 2021, In: Frontiers in Pharmacology. 12, 10 p., 644219.

Research output: Contribution to journal › Review article › peer-review

Open Access

44 Citations (Scopus)

Traditional Chinese medicine compounds regulate autophagy for treating neurodegenerative disease: A mechanism review

Wang, Z. Y., Liu, J., Zhu, Z., Su, C. F., Sreenivasmurthy, S. G., Iyaswamy, A., Lu, J. H., Chen, G., Song, J. X. & Li, M., Jan 2021, In: Biomedicine and Pharmacotherapy. 133, 14 p., 110968.

Research output: Contribution to journal › Review article › peer-review

Open Access

62 Citations (Scopus)

Transcription factor EB: an emerging drug target for neurodegenerative disorders

Song, J. X., Liu, J., Jiang, Y., Wang, Z. Y. & Li, M., Jan 2021, In: Drug Discovery Today. 26, 1, p. 164-172 9 p.

Research output: Contribution to journal › Review article › peer-review

30 Citations (Scopus)

2020

6-OH-BDE-47 exposure-induced Parkinson's disease pathology in Sprague Dawley rat

Ji, F., Zhu, Z., Zhang, M., Zhang, H., Zhu, L., Cai, X., Liu, W., Song, J., Li, M. & Cai, Z., 1 Apr 2020, In: Science of the Total Environment. 711, 135184.

Research output: Contribution to journal › Journal article › peer-review

9 Citations (Scopus)

A curcumin derivative activates TFEB and protects against parkinsonian neurotoxicity in vitro

Wang, Z., Yang, C., Liu, J., Tong, C. K. B., Zhu, Z., Malampati, S., Sreenivasmurthy, S. G., Cheung, K. H., Iyaswamy, A., Su, C., Lu, J., Song, J. & Li, M., 2 Feb 2020, In: International Journal of Molecular Sciences. 21, 4, 1515.

Research output: Contribution to journal › Journal article › peer-review

Open Access

File

38 Citations (Scopus)

23 Downloads (Pure)

A Mechanistic Review on Medicinal Mushrooms-Derived Bioactive Compounds: Potential Mycotherapy Candidates for Alleviating Neurological Disorders

Yadav, S. K., Ir, R., Jeewon, R., Doble, M., Hyde, K. D., Kaliappan, I., Jeyaraman, R., Reddi, R. N., Krishnan, J., Li, M. & Durairajan, S. S. K., 1 Nov 2020, In: Planta Medica. 86, 16, p. 1161-1175 15 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

37 Citations (Scopus)

A Self-Assembled α-Synuclein Nanoscavenger for Parkinson's Disease

Liu, J., Liu, C., Zhang, J., Zhang, Y., Liu, K., Song, J. X., Sreenivasmurthy, S. G., Wang, Z., Shi, Y., Chu, C., Zhang, Y., Wu, C., Deng, X., Liu, X., Song, J., Zhuang, R., Huang, S., Zhang, P., Li, M., Wen, L., & 2 othersZhang, Y. W. & Liu, G., 25 Feb 2020, In: ACS Nano. 14, 2, p. 1533-1549 17 p.

Research output: Contribution to journal › Journal article › peer-review

73 Citations (Scopus)

A small molecule transcription factor EB activator ameliorates beta-amyloid precursor protein and Tau pathology in Alzheimer's disease models

Song, J. X., Malampati, S., Zeng, Y., Durairajan, S. S. K., Yang, C., Tong, C. K. B., Iyaswamy, A., Shang, W. B., Sreenivasmurthy, S. G., Zhu, Z., Cheung, K. H., Lu, J. H., Tang, C., Xu, N. & Li, M., Feb 2020, In: Aging Cell. 19, 2, e13069.

Research output: Contribution to journal › Journal article › peer-review

Open Access

108 Citations (Scopus)

A stress response p38 MAP kinase inhibitor SB202190 promoted TFEB/TFE3-dependent autophagy and lysosomal biogenesis independent of p38

Yang, C., Zhu, Z., Tong, C. K. B., Iyaswamy, A., Xie, W. J., Zhu, Y., Sreenivasmurthy, S. G., Senthilkumar, K., Cheung, K. H., Song, J. X., Zhang, H. & Li, M., May 2020, In: Redox Biology. 32, 101445.

Research output: Contribution to journal › Journal article › peer-review

Open Access

39 Citations (Scopus)

Mr. & Mrs. Ko Chi Ming Centre for Parkinson's Disease Research

Research Output

Search results