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Dive into the research topics where Institute of Integrated Bioinformedicine & Translational Science is active. Topic labels come from the works of this unit's members. Together they form a unique fingerprint.
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Exploring the role of S100A9 in mediating failure of anti-TNF therapy in RA
LYU, A. (PI) & LIANG, C. (CoI)
1/01/25 → 31/12/26
Project: Research project
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Decoding the function of ceRNA-mediated hierarchical regulatory network and constructing its online framework
GUAN, D. (PI)
Project: Research project
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Translational medicine and precision medicine in bone and joint diseases
LIANG, C. (PI)
1/01/20 → 31/12/22
Project: Research project
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Adipocytic sclerostin loop3-LRP4 interaction required by sclerostin to impair whole-body lipid and glucose metabolism
Jiang, H., Tao, X., Yu, S., Zhang, Y., Ma, Y., Li, N., Wang, S., Zhang, N., Yang, X., Ding, S., Zhong, C., Li, H., Li, Z., Wen, X., Zhang, H., Chen, Z., Sun, M., Luo, H., Ren, M. & Lei, C. & 9 others, , 16 Jan 2026, In: Nature Communications. 17, 18 p., 1812.Research output: Contribution to journal › Journal article › peer-review
Open Access1 Citation (Scopus) -
AI-powered therapeutic aptamer drug discovery: Targeting the CT-domain of CTGF for duchenne muscular dystrophy
Yao, S. (Co-first author), Yang, X. (Co-first author), Ren, M. (Co-first author), Zhang, H. (Co-first author), Yu, S. (Co-first author), Chen, T., Ding, S., Pan, Y., Wang, L., Ma, Y., Kang, W., Peng, X., Liu, J., Lyu, A., Zhang, Z., Yu, Y., He, Y., Zhang, G. & Zhang, B. T., 26 Feb 2026, (E-pub ahead of print) In: Acta Pharmaceutica Sinica B. 23 p.Research output: Contribution to journal › Journal article › peer-review
Open Access -
Design, Synthesis, and Evaluation of Nucleolin-Bridged, MDM2-Recruiting IRAK4 Degraders for the Treatment of Autoimmune Diseases
Feng, Z., Zhang, X., Ding, Y., Zhang, K., Qiu, F., Xie, D., Lu, A., Zhang, L. & Liang, C., 26 Feb 2026, In: Journal of Medicinal Chemistry. 69, 4, p. 4855-4872 18 p.Research output: Contribution to journal › Journal article › peer-review
Activities
- 1 Membership of board/committee/council
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Guangdong‐Hong Kong-Macao Greater Bay Area International Research Platform for Aptamer‐Based Translational Medicine and Drug Discovery (External organisation)
YU, Y. (Committee/panel/advisory board member), LYU, A. (Director/non-executive director), ZHANG, G. (Director/non-executive director), LIU, J. (Working group member), LI, F. (Working group member) & MA, Y. (Working group member)
2017 → …Activity: Membership › Membership of board/committee/council