Research output per year
Research output per year
- 1 - 50 out of 2,714 results
Search results
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2024
20(S)-Ginsenoside Rh2 induces apoptosis and autophagy in melanoma cells via suppressing Src/STAT3 signaling
Li, J. K., Jiang, X. L., Zhang, Z., Chen, W. Q., Peng, J. J., Liu, B., Yung, K. K. L. & Zhu, P. L., Nov 2024, In: Journal of Ginseng Research. 48, 6, p. 559-569 11 p.Research output: Contribution to journal › Journal article › peer-review
Open Access -
Abietane diterpenoids from Isodon amethystoides and their biological activities
Zhou, L., Zhao, C. L., Xu, C. Y., Dong, M. H., Ye, J. H., Zhang, J. J., Pan, L. T., Zou, J. & Zhang, H. J., Sept 2024, In: Phytochemistry. 225, 10 p., 114171.Research output: Contribution to journal › Journal article › peer-review
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A critical review on intestinal mucosal barrier protection effects of dietary polysaccharides
Yan, W., Luo, J., Yu, Z. & Xu, B., Jan 2024, In: Food and Function. 15, 2, p. 481-492 12 p.Research output: Contribution to journal › Review article › peer-review
5 Citations (Scopus) -
A cross-disease, pleiotropy-driven approach for therapeutic target prioritization and evaluation
Bao, C., Tan, T., Wang, S., Gao, C., Lu, C., Yang, S., Diao, Y., Jiang, L., Jing, D., Chen, L., Lv, H. & Fang, H., 22 Apr 2024, In: Cell Reports Methods. 4, 4, 21 p., 100757.Research output: Contribution to journal › Journal article › peer-review
Open AccessFile1 Citation (Scopus)43 Downloads (Pure) -
Activation of APE1 modulates Nrf2 protected against acute liver injury by inhibit hepatocyte ferroptosis and promote hepatocyte autophagy
Diao, J., Fan, H., Zhang, J., Fu, X., Liao, R., Zhao, P., Huang, W., Huang, S., Liao, H., Yu, J., Pan, D., Wang, M., Xiao, W. & Wen, X., 20 Feb 2024, In: International Immunopharmacology. 128, 11 p., 111529.Research output: Contribution to journal › Journal article › peer-review
Open Access -
Activation of hepatic adenosine A1 receptor ameliorates MASH via inhibiting SREBPs maturation
Zhu, W., Hong, Y., Tong, Z., He, X., Li, Y., Wang, H., Gao, X., Song, P., Zhang, X., Wu, X., Tan, Z., Huang, W., Liu, Z., Bao, Y., Ma, J., Zheng, N., Xie, C., Ke, X., Zhou, W. & Jia, W. & 4 others, , 19 Mar 2024, In: Cell Reports Medicine. 5, 3, 28 p., 101477.Research output: Contribution to journal › Journal article › peer-review
Open Access1 Citation (Scopus) -
Add-on astragalus in type 2 diabetes and chronic kidney disease: A multi-center, assessor-blind, randomized controlled trial
Chan, K. W., Kwong, A. S. K., Tsui, P. N., Chan, G. C. W., Choi, W. F., Yiu, W. H., Cheung, S. C. Y., Wong, M. M. Y., Zhang, Z. J., Tan, K. C. B., Lao, L., Lai, K. N., Tang, S. C. W. & READY and SCHEMATIC research group, 25 Jul 2024, In: Phytomedicine. 130, 11 p., 155457.Research output: Contribution to journal › Journal article › peer-review
1 Citation (Scopus) -
ADMETlab 3.0: an updated comprehensive online ADMET prediction platform enhanced with broader coverage, improved performance, API functionality and decision support
Fu, L., Shi, S., Yi, J., Wang, N., He, Y., Wu, Z., Peng, J., Deng, Y., Wang, W., Wu, C., Lyu, A., Zeng, X., Zhao, W., Hou, T. & Cao, D., 5 Jul 2024, In: Nucleic Acids Research. 52, W1, p. W422-W431 10 p.Research output: Contribution to journal › Journal article › peer-review
Open Access48 Citations (Scopus) -
Advancing targeted combination chemotherapy in triple negative breast cancer: nucleolin aptamer-mediated controlled drug release
Ma, Y., Xie, D., Chen, Z., Shen, X., Wu, X., Ding, F., Ding, S., Pan, Y., Li, F., Lu, A. & Zhang, G., 1 Jul 2024, In: Journal of Translational Medicine. 22, 1, 13 p., 604.Research output: Contribution to journal › Journal article › peer-review
Open Access1 Citation (Scopus) -
Aloperine Suppresses Cancer Progression by Interacting with VPS4A to Inhibit Autophagosome-lysosome Fusion in NSCLC
Guo, W., Zhou, H., Wang, J., Lu, J., Dong, Y., Kang, Z., Qiu, X., Ouyang, X., Chen, Q., Li, J., Cheng, X., Du, K., Li, M., Lin, Z., Jin, M., Zhang, L., Sarapultsev, A., Shi, K., Li, F. & Zhang, G. & 8 others, , 21 Aug 2024, In: Advanced Science. 11, 31, 21 p., 2308307.Research output: Contribution to journal › Journal article › peer-review
Open Access -
A Novel Multiple-Network Analysis Integrating Metabolomics and Pharmacology for Mechanism Study of Medicine: A Case Study of CDD-2101 Against Constipation
Shi, J., Xiang, L., Lam, Y. Y., Ning, Z., Liu, J., Li, Y., Zhou, Y., Zhai, L., Lin, C., Zhu, L. & Bian, Z., Dec 2024, In: Journal of Analysis and Testing. 8, 4, p. 415–430 16 p.Research output: Contribution to journal › Journal article › peer-review
Open Access1 Citation (Scopus) -
Aptamer AS411 interacts with the KRAS promoter/hnRNP A1 complex and shows increased potency against drug-resistant lung cancer
Zhu, Y., Li, X., Zhang, Q., Yang, X., Sun, X., Pan, Y., Yuan, X., Ma, Y., Xu, B. & Yang, Z., 1 May 2024, In: RSC Medicinal Chemistry. 15, 5, p. 1515-1526 12 p.Research output: Contribution to journal › Journal article › peer-review
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Aptamer Functionalized Hypoxia-potentiating Agent and Hypoxia-inducible Factor Inhibitor Combined with Hypoxia-activated Prodrug for Enhanced Tumor Therapy
Ma, Y., Zhang, H., Shen, X., Yang, X., Deng, Y., Tian, Y., Chen, Z., Pan, Y., Luo, H., ZHONG, C., Yu, S., Lu, A., Zhang, B., Tang, T. & Zhang, G., 28 Aug 2024, In: Cancer Letters. 598, 12 p., 217102.Research output: Contribution to journal › Journal article › peer-review
Open Access2 Citations (Scopus) -
Are Tai Chi and Qigong effective in the treatment of traumatic brain injury? A systematic review
Laskosky, N. A., Huston, P., Lam, W. C., Anderson, C. & Zhong, L. L. D., 6 Feb 2024, In: BMC Complementary Medicine and Therapies. 24, 1, 13 p., 78.Research output: Contribution to journal › Journal article › peer-review
Open Access -
Artesunate treats obesity in male mice and non-human primates through GDF15/GFRAL signalling axis
Guo, X., Asthana, P., Zhai, L., Cheng, K. W., Gurung, S., Huang, J., Wu, J., Zhang, Y., Mahato, A. K., Saarma, M., Ustav, M., Kwan, H. Y., Lyu, A., Chan, K. M., Xu, P., Bian, Z. X. & Wong, H. L. X., 3 Feb 2024, In: Nature Communications. 15, 1, 14 p., 1034.Research output: Contribution to journal › Journal article › peer-review
Open Access5 Citations (Scopus) -
Artificial intelligence with mass spectrometry-based multimodal molecular profiling methods for advancing therapeutic discovery of infectious diseases
Liu, J., Bao, C., Zhang, J., Han, Z., Fang, H. & Lu, H., Nov 2024, In: Pharmacology and Therapeutics. 263, 108712.Research output: Contribution to journal › Journal article › peer-review
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Aspartame Causes Developmental Defects and Teratogenicity in Zebra Fish Embryo: Role of Impaired SIRT1/FOXO3a Axis in Neuron Cells
Pandaram, A., Paul, J., Wankhar, W., Thakur, A., Verma, S., Vasudevan, K., Wankhar, D., Kammala, A. K., Sharma, P., Jaganathan, R., Iyaswamy, A. & Rajan, R., Apr 2024, In: Biomedicines. 12, 4, 19 p., 855.Research output: Contribution to journal › Journal article › peer-review
Open Access4 Citations (Scopus) -
A systematic approach for authentication of medicinal Patrinia species using an integration of morphological, chemical and molecular methods
Wong, K.-H., Zhang, T., Yue, G. G. L., Li, M.-C., Wu, H. Y., Tong, M. H., Zhao, X.-L., Chen, H., Lau, C. B. S., Shaw, P. C. & Lau, D. T. W., 19 Mar 2024, In: Scientific Reports. 14, 1, 14 p., 6566.Research output: Contribution to journal › Journal article › peer-review
Open AccessFile1 Citation (Scopus)20 Downloads (Pure) -
Atractylenolide II combined with Interferon-γ synergistically ameliorates colorectal cancer progression in vivo and in vitro by blocking the NF-kB p65/PD-L1 pathway
Wu, Y., Dai, S., Zhang, Y. J., Li, Z., Zhu, B., Liu, Q., Wo, L., Yu, Z., Yuan, X. & Dou, X., 11 Jun 2024, In: Journal of Cancer. 15, 13, p. 4328-4344 17 p.Research output: Contribution to journal › Journal article › peer-review
Open Access -
Bile acid signaling in the regulation of whole body metabolic and immunological homeostasis
Jia, W., Li, Y., Cheung, K. C. P. & Zheng, X., May 2024, In: Science China Life Sciences. 67, 5, p. 865–878 14 p.Research output: Contribution to journal › Journal article › peer-review
29 Citations (Scopus) -
Biotin-decorated celastrol-loaded ZIF-8 nanoparticles induce ferroptosis for colorectal cancer therapy
Chen, J., Liu, Y., You, Y., Zhou, R., Li, Y., Zhou, X., Chen, X., Yang, Y., Chen, J., Kwan, H. Y., Zhao, X. & Wu, Y., Mar 2024, In: Materials and Design. 239, 13 p., 112814.Research output: Contribution to journal › Journal article › peer-review
Open Access2 Citations (Scopus) -
CD31 orchestrates metabolic regulation in autophagy pathways of rheumatoid arthritis
Cheung, K. C. P., Ma, J., Wang, L., Chen, X., Fanti, S., Li, M., Azevedo, L. R., Gosselet, F., Shen, H., Zheng, X., Lu, A. & Jia, W., Sept 2024, In: Pharmacological Research. 207, 12 p., 107346.Research output: Contribution to journal › Journal article › peer-review
Open AccessFile51 Downloads (Pure) -
Centipeda minima (L.) A. Braun & Asch. and its representative active compound alleviate DSS-induced ulcerative colitis via inhibition of NLRP3 inflammasome activation and regulation of gut microbiota
Tan, J., Wang, S., Gan, S., Chen, H., Zhong, K., Kwan, H. Y., Fan, X., Xiao, B., Liang, Q., Liu, Z. & Su, T., Jun 2024, In: Journal of Functional Foods. 117, 12 p., 106207.Research output: Contribution to journal › Journal article › peer-review
Open Access -
ChemFH: an integrated tool for screening frequent false positives in chemical biology and drug discovery
Shi, S., Fu, L., Yi, J., Yang, Z., Zhang, X., Deng, Y., Wang, W., Wu, C., Zhao, W., Hou, T., Zeng, X., Lyu, A. & Cao, D., 5 Jul 2024, In: Nucleic Acids Research. 52, W1, p. W439–W449 11 p.Research output: Contribution to journal › Journal article › peer-review
Open Access -
ChemMORT: an automatic ADMET optimization platform using deep learning and multi-objective particle swarm optimization
Yi, J. C., Yang, Z. Y., Zhao, W. T., Yang, Z. J., Zhang, X. C., Wu, C. K., Lu, A. P. & Cao, D. S., Mar 2024, In: Briefings in Bioinformatics. 25, 2, 10 p., bbae008.Research output: Contribution to journal › Journal article › peer-review
Open Access3 Citations (Scopus) -
Comparation of abdominal aortic balloon occlusion versus uterine artery embolization in the treatment of cesarean scar pregnancy
Rui, T., Wei, H., Huaibo, J., Han, M., Cheung, K. C. P. & Yang, C., 25 Oct 2024, In: Frontiers in Medicine. 11, 8 p., 1472239.Research output: Contribution to journal › Journal article › peer-review
Open Access -
Connective Tissue Growth Factor: Regulation, Diseases, and Drug Discovery
Ren, M., Yao, S., Chen, T., Luo, H., Tao, X., Jiang, H., Yang, X., Zhang, H., Yu, S., Wang, Y., Lu, A. & Zhang, G., 1 May 2024, In: International Journal of Molecular Sciences. 25, 9, 23 p., 4692.Research output: Contribution to journal › Review article › peer-review
Open Access -
Corynoxine promotes TFEB/TFE3-mediated autophagy and alleviates Aβ pathology in Alzheimer’s disease models
Guan, X.-J., Deng, Z.-Q., Liu, J., Su, C.-F., Tong, B. C. K., Zhu, Z., Sreenivasmurthy, S. G., Kan, Y.-X., Lu, K., Chu, C. P. K., Pi, R.-B., Cheung, K.-H., Iyaswamy, A., Song, J.-X. & Li, M., May 2024, In: Acta Pharmacologica Sinica. 45, 5, p. 900–913 14 p.Research output: Contribution to journal › Journal article › peer-review
9 Citations (Scopus) -
CRISPRa engineered Elite macrophages enable adoptive cell therapy for rheumatoid arthritis
Huang, Y., Wang, Z., Zhong, C., Chen, H., Chen, X., Cao, C., Qiu, F., Xie, D., Li, J., Li, J., Yang, X., Lu, A., Fu, X. & Liang, C., 20 Mar 2024, In: The Innovation Medicine. 2, 1, 20 p., 100050.Research output: Contribution to journal › Journal article › peer-review
Open Access -
Critical review on the research of chemical structure, bioactivities, and mechanism of actions of Dendrobium officinale polysaccharide
Lai, C. H., Huo, C. Y., Xu, J., Han, Q. B. & Li, L. F., Apr 2024, In: International Journal of Biological Macromolecules. 263, 12 p., 130315.Research output: Contribution to journal › Journal article › peer-review
8 Citations (Scopus) -
Design and synthesis of nucleotidyl lipids and their application in the targeted delivery of siG12D for pancreatic cancer therapy
Pan, Y., Zhu, Y., Ma, Y., Hong, J., Zhao, W., Gao, Y., Guan, J., Ren, R., Zhang, Q., Yu, J., Guan, Z. & Yang, Z., Mar 2024, In: Biomedicine and Pharmacotherapy. 172, 14 p., 116239.Research output: Contribution to journal › Journal article › peer-review
Open Access1 Citation (Scopus) -
Design of clinical trials in integrative medicine: The issue of personalization
Chan, K. W., Liu, J. P. & Bian, Z. X., Jun 2024, In: European Journal of Integrative Medicine. 68, 102365.Research output: Contribution to journal › Journal article › peer-review
2 Citations (Scopus) -
Determination of mycobiota and aflatoxin contamination in commercial bee pollen from eight provinces and one autonomous region of China
Guo, M., Zhang, J., Wang, Y., Chen, H., Lv, J., Kong, D., Jin, Z., Ke, T., Zhang, H., Luo, J. & Yang, M., 2 Feb 2024, In: International Journal of Food Microbiology. 411, 110511.Research output: Contribution to journal › Journal article › peer-review
1 Citation (Scopus) -
Developing Stapled Aptamers with a Constrained Conformation for Osteogenesis Imperfect Therapeutics
Gubu , A., Zhang, G., Jing, N. & Ma, Y., 14 Nov 2024, In: Journal of Medicinal Chemistry. 67, 21, p. 18883–18894 12 p.Research output: Contribution to journal › Journal article › peer-review
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Development of a therapeutic monoclonal antibody against circulating adipocyte fatty acid binding protein to treat ischaemic stroke
Liao, B., Yang, S., Geng, L., Zong, J., Zhang, Z., Jiang, M., Jiang, X., Li, S., Xu, A., Chang, J. & Hoo, R. L. C., Apr 2024, In: British Journal of Pharmacology. 181, 8, p. 1238-1255 18 p.Research output: Contribution to journal › Journal article › peer-review
Open Access2 Citations (Scopus) -
Dietary ellagic acid therapy for CNS autoimmunity: Targeting on Alloprevotella rava and propionate metabolism
Han, B., Shi, L., Bao, M. Y., Yu, F. L., Zhang, Y., Lu, X. Y., Wang, Y., Li, D. X., Lin, J. C., Jia, W., Li, X. & Zhang, Y., 24 Jun 2024, In: Microbiome. 12, 1, 18 p., 114.Research output: Contribution to journal › Journal article › peer-review
Open Access2 Citations (Scopus) -
Discovery of a core inflammatory gene network associated with poor prognosis and characterized immune infiltration pattern in pancreatic ductal adenocarcinoma
Yang, L., Chen, Z., Sheng, Y., Chowdhury, D., Yip, H. F., Qiao, S., Sun, M., Lu, A. & Li, F., 15 Jan 2024, In: Cancer Research. 84, 2 (Supplement), C042.Research output: Contribution to journal › Conference article › peer-review
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Discovery of plasma biomarkers for Parkinson's disease diagnoses based on metabolomics and lipidomics
Wang, X., Wang, B., Ji, F., Yan, J., Fang, J., Zhang, D., Xu, J., Ji, J., Hao, X., Luan, H., Hong, Y., Qiu, S., Li, M., Yang, Z., Liu, W., Cai, X. & Cai, Z., Nov 2024, In: Chinese Chemical Letters. 35, 11, 109653.Research output: Contribution to journal › Journal article › peer-review
1 Citation (Scopus) -
Discovery of the small molecular inhibitors against sclerostin loop3 as potential anti-osteoporosis agents by structural based virtual screening and molecular design
Yu, S., Huang, W., Zhang, H., Guo, Y., Zhang, B., Zhang, G. & Lei, J., 5 May 2024, In: European Journal of Medicinal Chemistry. 271, 9 p., 116414.Research output: Contribution to journal › Journal article › peer-review
2 Citations (Scopus) -
Diversified Chemical Structures and Bioactivities of the Chemical Constituents Found in the Brown Algae Family Sargassaceae
Peng, Y., Yang, X., Huang, R., Ren, B., Chen, B., Liu, Y. & Zhang, H., 24 Jan 2024, In: Marine Drugs. 22, 2, 30 p., 59.Research output: Contribution to journal › Review article › peer-review
Open Access1 Citation (Scopus) -
Does the Dose of Standard Adjuvant Chemotherapy Affect the Triple-negative Breast Cancer Benefit from Extended Capecitabine Metronomic Therapy? An Exploratory Analysis of the SYSUCC-001 Trial
Chen, Y., Li, W. X., Wu, J. H., Chen, G. H., Yang, C. M., Lu, H., Wang, X., Wang, S. S., Huang, H., Cai, L., Zhao, L., Peng, R. J., Lin, Y., Tang, J., Zeng, J., Zhang, L. H., Ke, Y. L., Wang, X. M., Liu, X. M. & Zhang, A. Q. & 21 others, , 12 Apr 2024, In: Breast Cancer: Targets and Therapy. 16, p. 223-231 9 p.Research output: Contribution to journal › Journal article › peer-review
Open Access2 Citations (Scopus) -
Editorial for the Special Issue “Cytokines in Inflammatory Signaling”
Chong, W. P., 1 Jun 2024, In: International Journal of Molecular Sciences. 25, 11, 3 p., 5799.Research output: Contribution to journal › Editorial
Open Access -
Effect of home-based acupressure on constipation in people with spinal cord injury: A study protocol for a randomized controlled trial with a mixed-method approach
Li, Y., Li, J., Li, M., Ho, Y. S., Sun, T. C., Wang, S., Wong, W. K., Zhang, S., Kwan, R., Wong, A. Y. & Yeung, W. F., Jun 2024, In: European Journal of Integrative Medicine. 68, 8 p., 102360.Research output: Contribution to journal › Journal article › peer-review
Open Access1 Citation (Scopus) -
Effect of Huaier granule on prognosis of breast cancer: A single-center propensity score matching retrospective study
Guo, Q., Peng, Y., Zhang, G., Lin, H. & Chen, Q., 25 Jan 2024, (E-pub ahead of print) In: Chinese Medical Journal. 6 p.Research output: Contribution to journal › Journal article › peer-review
Open Access -
Efficacy and Safety of Chinese Herbal Formula CDD-2103 for Remission Maintenance of Ulcerative Colitis: Study Protocol for a Randomized, Double-blinded, Placebo-controlled Trial
Zhang, X., Tan, H. Y., To, W. L., Ning, Z., Cheng, K. W., Zhang, J., Au, E., Zhou, K., Wong, H. K., Mok, H. L., Xu, J., Koh, M. & Bian, Z., Aug 2024, In: European Journal of Integrative Medicine. 69, 7 p., 102375.Research output: Contribution to journal › Journal article › peer-review
Open Access5 Downloads (Pure) -
Efficacy and safety of Chinese herbal medicine to prevent and treat COVID-19 household close contacts in Hong Kong: an open-label, randomized controlled trial
Du, P., Lam, W. C., Leung, C., Li, H., Lyu, Z., Yuen, C. S., Cheung, C. H., Lam, T. F., Bian, Z. & Zhong, L., 10 May 2024, In: Frontiers in Immunology. 15, 11 p., 1359331.Research output: Contribution to journal › Journal article › peer-review
Open Access -
Electro-acupuncture for central obesity: a patient-assessor blinded, randomized sham-controlled clinical trial
Lam, T. F., Lyu, Z., Wu, X., Wong, Y. P., Cao, P., Wong, E. Y., Hung, H. B., Zhang, S., Bian, Z. & Zhong, L. L. D., 29 Jan 2024, In: BMC Complementary Medicine and Therapies. 24, 1, 10 p., 62.Research output: Contribution to journal › Journal article › peer-review
Open Access5 Citations (Scopus) -
Elevated extracellular matrix protein 1 in circulating extracellular vesicles supports breast cancer progression under obesity conditions
Xu, K., Fu, A., Li, Z., Miao, L., Lou, Z., Jiang, K., Lau, C., Su, T., Tong, T., Bao, J., Lu, A. & Kwan, H. Y., 24 Feb 2024, In: Nature Communications. 15, 1, 17 p., 1685.Research output: Contribution to journal › Journal article › peer-review
Open Access1 Citation (Scopus) -
Enhancing Multi-species Liver Microsomal Stability Prediction through Artificial Intelligence
Long, T. Z., Jiang, D. J., Shi, S. H., Deng, Y. C., Wang, W. X. & Cao, D. S., 22 Apr 2024, In: Journal of Chemical Information and Modeling. 64, 8, p. 3222-3236 15 p.Research output: Contribution to journal › Journal article › peer-review
4 Citations (Scopus) -
EXOSOMAL COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASES
LI, M. (Inventor), IYASWAMY, A. (Inventor), Chen, H. J. (Inventor) & Thakur, A. (Inventor), 18 Jul 2024, IPC No. A61-LM-Fe65-PT01, 9 Jan 2024, Priority date 13 Jan 2023, Priority No. PCT/CN2024/071455Research output: Patent