Chinese Medicine - Clinical Division - Research Output

2024

Artesunate treats obesity in male mice and non-human primates through GDF15/GFRAL signalling axis

Guo, X., Asthana, P., Zhai, L., Cheng, K. W., Gurung, S., Huang, J., Wu, J., Zhang, Y., Mahato, A. K., Saarma, M., Ustav, M., Kwan, H. Y., Lyu, A., Chan, K. M., Xu, P., Bian, Z. X. & Wong, H. L. X., 3 Feb 2024, In: Nature Communications. 15, 1, 14 p., 1034.

Research output: Contribution to journal › Journal article › peer-review

Open Access

8 Citations (Scopus)

Artificial intelligence with mass spectrometry-based multimodal molecular profiling methods for advancing therapeutic discovery of infectious diseases

Liu, J., Bao, C., Zhang, J., Han, Z., Fang, H. & Lu, H., Nov 2024, In: Pharmacology and Therapeutics. 263, 108712.

Research output: Contribution to journal › Journal article › peer-review

BindingSiteDTI: differential-scale binding site modelling for drug–target interaction prediction

Pan, F., Yin, C., Liu, S. Q., Huang, T., Bian, Z. & Yuen, P. C., May 2024, In: Bioinformatics. 40, 5, 8 p., btae308.

Research output: Contribution to journal › Journal article › peer-review

Open Access

1 Citation (Scopus)

Case report: Staged tension-reducing excision of giant acquired vulvar lymphangioma secondary to cervical cancer surgery

Hu, L. J., Fang, H. M., Lin, H. M., Kang, X., Lin, Y. & Xiao, J., 6 Sept 2024, In: Frontiers in Oncology. 14, 5 p., 1418829.

Research output: Contribution to journal › Journal article › peer-review

Open Access

Chinese herbal medicine combined with Western medicine for Mycoplasma pneumoniae pneumonia in children: An overview of systematic reviews

Zhang, S., Zhang, X., Cui, Y., Huang, J., Fan, F., Wang, S. & Han, F., Jan 2024, In: Journal of Traditional Chinese Medical Sciences. 11, 1, p. 131-139 9 p.

Research output: Contribution to journal › Journal article › peer-review

Open Access

Effects of different treatment frequencies of electromagnetic stimulation for urinary incontinence in women: Study protocol for a randomized controlled trial

Chen, C., Zhang, J., Zhang, H., Li, H., Yu, J., Yao, P. & Fang, Y., 26 Apr 2024, In: Trials. 25, 1, 11 p., 285.

Research output: Contribution to journal › Journal article › peer-review

Open Access

Efficacy and Safety of Chinese Herbal Formula CDD-2103 for Remission Maintenance of Ulcerative Colitis: Study Protocol for a Randomized, Double-blinded, Placebo-controlled Trial

Zhang, X., Tan, H. Y., To, W. L., Ning, Z., Cheng, K. W., Zhang, J., Au, E., Zhou, K., Wong, H. K., Mok, H. L., Xu, J., Koh, M. & Bian, Z., Aug 2024, In: European Journal of Integrative Medicine. 69, 7 p., 102375.

Research output: Contribution to journal › Journal article › peer-review

Open Access

5 Downloads (Pure)

Efficacy and safety of Chinese herbal medicine to prevent and treat COVID-19 household close contacts in Hong Kong: an open-label, randomized controlled trial

Du, P., Lam, W. C., Leung, C., Li, H., Lyu, Z., Yuen, C. S., Cheung, C. H., Lam, T. F., Bian, Z. & Zhong, L., 10 May 2024, In: Frontiers in Immunology. 15, 11 p., 1359331.

Research output: Contribution to journal › Journal article › peer-review

Open Access

Electro-acupuncture for central obesity: a patient-assessor blinded, randomized sham-controlled clinical trial

Lam, T. F., Lyu, Z., Wu, X., Wong, Y. P., Cao, P., Wong, E. Y., Hung, H. B., Zhang, S., Bian, Z. & Zhong, L. L. D., 29 Jan 2024, In: BMC Complementary Medicine and Therapies. 24, 1, 10 p., 62.

Research output: Contribution to journal › Journal article › peer-review

Open Access

5 Citations (Scopus)

Evaluation of compliance of CONSORT-CHM formula 2017 in randomized controlled trials of Chinese herbal medicine formulas: protocol of a five-year review

Wang, J., Cheng, C. W., Jiao, Y., SHI, D., Wang, Y., LI, H., Wang, N., Wang, X., Li, Y., Liang, F., Luo, S., Han, F., Li, J., Wang, P., Lu, A., Bian, Z. & Zhang, X., 23 Feb 2024, In: Frontiers in Pharmacology. 15, 8 p., 1287262.

Research output: Contribution to journal › Journal article › peer-review

Open Access

1 Citation (Scopus)

Evaluation of the reliability and usability of CARE-Radiology: A descriptive-analytic study

Wang, M., Luo, X., Estill, J., Spruyt, K., Kurokawa, R., Persaud, N., Shimamura, Y., Raison, H., Franco, P. N., Maino, C., Elkhayat, H., Galal, R. A., Kimura, D., Omata, S., Ryzhkin, S. A., Izmailov, T. R., Bashirov, R. A., Bian, Z., Tian, J. & Lei, J., Sept 2024, In: Journal of Evidence-Based Medicine. 17, 3, p. 597-603 7 p.

Research output: Contribution to journal › Journal article › peer-review

Integrated metabolomics and serum-feces pharmacochemistry-based network pharmacology to reveal the mechanisms of an herbal prescription against ulcerative colitis

Cheng, K. W., Shi, J., Huang, C., Tan, H. Y., Ning, Z., Lyu, C., Xu, Y., Mok, H. L., Zhai, L., Xiang, L., Qin, H., Lin, C., Zhu, L. & Bian, Z., Aug 2024, In: Computers in Biology and Medicine. 178, 11 p., 108775.

Research output: Contribution to journal › Journal article › peer-review

Osteoprotegerin mediates adipogenesis in obesity

Lyu, Z., Chan, Y. T., Lu, Y., Fung Lam, T., Wu, X., Wu, J., Xu, L., Yang, W., Zhang, C., Lidan Zhong, L. & Wang, N., Aug 2024, In: Journal of Advanced Research. 62, p. 245-255 11 p.

Research output: Contribution to journal › Journal article › peer-review

Open Access

1 Citation (Scopus)

Placebo and Nocebo Responses in Pharmacological Trials of Tic Disorders: A Meta-Analysis

Wang, S., Xiong, Z., Cui, Y., Fan, F., Zhang, S., Jia, R., Hu, Y., Li, L., Zhang, X. & Han, F., Mar 2024, In: Movement Disorders. 39, 3, p. 585-595 11 p.

Research output: Contribution to journal › Journal article › peer-review

Open Access

3 Citations (Scopus)

Protocol for the reporting assessment of clinical trials with non-pharmacological therapies in Chinese medicine

Tan, H., Wang, N., Li, H., Cheng, C. W., Jiao, Y., Shi, D., Wang, J., Deng, J., Li, J., Han, F., Wang, P., Bian, Z. & Zhang, X., Aug 2024, In: European Journal of Integrative Medicine. 69, 12 p., 102381.

Research output: Contribution to journal › Journal article › peer-review

Open Access

1 Citation (Scopus)

Reporting characteristics and quality of randomized controlled trial protocols in traditional Chinese medicine: a cross-sectional study

Zhang, L., Li, H., Hu, L., Ou, X., Tan, H., Zhang, X., Lau, C. T., Lu, A., Bian, Z. & Zhang, X., 7 Jun 2024, In: Frontiers in Pharmacology. 15, 16 p., 1389808.

Research output: Contribution to journal › Journal article › peer-review

Open Access

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20 Downloads (Pure)

Suboptimal reporting of randomized controlled trials on non-pharmacological therapies in Chinese medicine

Zhang, X., Li, H., Tan, H., Wang, N., Cheng, C. W., Wang, J., Shi, D., Zhang, L., Liu, Y., Wang, Y., Luo, S., Lin, Y., Hu, L., Zhang, X., Li, J., Han, F., Wang, P., Lu, A. & Bian, Z., Oct 2024, In: Frontiers of Medicine. 18, 5, p. 798-813 16 p.

Research output: Contribution to journal › Journal article › peer-review

Synergisitic anti-colorectal cancer effects of WNT974 combined with artesunate via cooperative regulation of p21, p27, and AKT

Gong, R. H., Chen, M., Huang, C., Wong, H. L. X., Chen, S., Bian, Z. & Chen, G. Q., Sept 2024, In: Pharmacological Research - Modern Chinese Medicine. 12, 11 p., 100498.

Research output: Contribution to journal › Journal article › peer-review

Open Access

The Impact of Social Media Use on Sleep and Mental Health in Youth: a Scoping Review

Yu, D. J., Wing, Y. K., Li, T. M. H. & Chan, N. Y., Mar 2024, In: Current Psychiatry Reports. 26, 3, p. 104-119 16 p.

Research output: Contribution to journal › Journal article › peer-review

Open Access

7 Citations (Scopus)

Transparency and reporting characteristics of randomized controlled trials with Chinese herbal medicine formulas interventions

Wang, J., Shi, D., Wang, Y., Zhang, X., Li, H., Wang, X., Luo, S., Hu, L., Deng, J., Zhang, L., Lau, C. T., Cheng, C. W., Han, F., Li, J., Wang, P., Lyu, A., Bian, Z. & Zhang, X., Aug 2024, In: Frontiers of Medicine. 18, 4, p. 757–761 5 p.

Research output: Contribution to journal › Journal article › peer-review

中醫藥臨床試驗報告規範在醫學期刊中的應用情況

Translated title of the contribution: Application status of reporting guidelines of TCM clinical studies in medical journals李涵 & 張軒, Jan 2024, In: 香港中醫雜誌. 19, 1, p. 56-60 5 p.

Research output: Contribution to journal › Journal article › peer-review

人工智能技術在中醫臨床試驗中的應用現狀與問題淺析

Translated title of the contribution: The current appliction status and analysis of the problems associated with artificial intelligence used in clinical trials of Chinese medicine趙宣博 & 張軒, Jul 2024, In: 香港中醫雜誌. 19, 3, p. 19-22 4 p.

Research output: Contribution to journal › Journal article › peer-review

Open Access

基于“中医整体观”探讨针刺补泻手法治疗膝关节炎的运用

Translated title of the contribution: Application of Acupuncture Manipulation for Reinforcement and Reduction in Treating Knee Osteoarthritis from the Holistic View of Traditional Chinese Medicine陈欣红, 唐平, 张全明 & 柯兰, 20 Jun 2024, In: 基层中医药. 3, 6, p. 94-99 6 p.

Research output: Contribution to journal › Journal article › peer-review

2023

A cross-sectional study of the endorsement proportion of reporting guidelines in 1039 Chinese medical journals

Duan, Y., Zhao, L., Ma, Y., Luo, J., Chen, J., Miao, J., Zhang, X., Moher, D. & Bian, Z., 21 Jan 2023, In: BMC Medical Research Methodology. 23, 10 p., 20.

Research output: Contribution to journal › Journal article › peer-review

Open Access

5 Citations (Scopus)

Acupuncture for chemotherapy-associated insomnia in breast cancer patients: An assessor-participant blinded, randomized, sham-controlled trial

Zhang, J., Qin, Z., So, T. H., Chang, T. Y., Yang, S., Chen, H., Yeung, W. F., Chung, K. F., Chan, P. Y., Huang, Y., Xu, S., Chiang, C. Y., Lao, L. & Zhang, Z.-J., 26 Apr 2023, In: Breast Cancer Research. 25, 15 p., 49.

Research output: Contribution to journal › Journal article › peer-review

Open Access

19 Citations (Scopus)

Acupuncture for olfactory dysfunction in infected COVID-19 patients: Study protocol for a randomized, sham-controlled clinical trial

Zhong, L. L., Wong, Y., Leung, C., Choy, C., Cho, H., Wong, A. Y., Yau, K., Wong, R. H., Ng, B. F. & Bian, Z., Jan 2023, In: Journal of Traditional Chinese Medical Sciences. 10, 1, p. 118-124 7 p.

Research output: Contribution to journal › Journal article › peer-review

Open Access

Acupuncture versus sham acupuncture and usual care for Antiandrogen-Induced hot fLashes in prostate cancer (AVAIL): Study protocol for a randomized clinical trial

Qin, Z., Zang, Z., Yu, J., Lv, J., Li, N., Zhang, J., Yang, M., Kwong, J. S. W., Pang, R., Wang, J., Cui, Z., Yu, Y., Wang, H., Zhu, Y., Yuan, Y., Li, X., Wu, Y. & Wu, J., 27 Oct 2023, In: BMC Complementary Medicine and Therapies. 23, 8 p., 388.

Research output: Contribution to journal › Journal article › peer-review

Open Access

Altered gut microbiota–host bile acid metabolism in IBS-D patients with liver depression and spleen deficiency pattern

Du, L., Zhang, Z., Zhai, L., Xu, S., Yang, W., Huang, C., Lin, C., Zhong, L. L. D., Bian, Z. & Zhao, L., 19 Jul 2023, In: Chinese Medicine. 18, 13 p., 87.

Research output: Contribution to journal › Journal article › peer-review

Open Access

6 Citations (Scopus)

Comparative efficacy of traditional Chinese herbal injection for chronic renal failure: A systematic review and network meta-analysis of randomized controlled trials

Shi, D., Liang, F., Wang, X., Wang, N., Zhang, L., Cui, W., Deng, J., Lau, C. T., Zhang, L. & Zhang, X., Jan 2023, In: Journal of Traditional Chinese Medical Sciences. 10, 1, p. 83-99 17 p.

Research output: Contribution to journal › Journal article › peer-review

Open Access

Comparison of moderate and vigorous walking exercise on reducing depression in middle-aged and older adults: A pilot randomized controlled trial

Yu, D. J., Yu, A. P., Leung, C. K., Chin, E. C., Fong, D. Y., Cheng, C. P., Yau, S. Y. & Siu, P. M., Jun 2023, In: European Journal of Sport Science. 23, 6, p. 1018-1027 10 p.

Research output: Contribution to journal › Journal article › peer-review

15 Citations (Scopus)

Construction of a virtual reality platform for computer-aided navigation Lingnan bone setting technique

Huang, R., Xu, Z., Guan, H., Zhou, J., Yang, K., Peng, S., Yu, H., Fu, M., He, L., Zhu, Y., Jiang, Y., Zhang, G., Zhou, H. & Chow, C. H., 1 Dec 2023, In: Bioengineered. 14, 1, p. 165-178 14 p.

Research output: Contribution to journal › Journal article › peer-review

Open Access

1 Citation (Scopus)

Dose–response effects of exercise and caloric restriction on visceral adiposity in overweight and obese adults: a systematic review and meta-analysis of randomised controlled trials

Recchia, F., Leung, C. K., Yu, A. P., Leung, W., Yu, D. J., Fong, D. Y., Montero, D., Lee, C. H., Wong, S. H. S. & Siu, P. M., Aug 2023, In: British Journal of Sports Medicine. 57, 16, p. 1035-1041 7 p.

Research output: Contribution to journal › Journal article › peer-review

Open Access

22 Citations (Scopus)

Effectiveness of Chinese Herbal Medicine in Patients with COVID-19 During the Omicron Wave in Hong Kong: A Retrospective Case-Controlled Study

Zhang, J., Luo, J., Tang, H. T., Wong, H. K., Ma, Y., Xie, D., Peng, B., Lyu, A., Cheung, C. H. & Bian, Z., Aug 2023, In: The American Journal of Chinese Medicine. 51, 7, p. 1615-1626 12 p.

Research output: Contribution to journal › Journal article › peer-review

1 Citation (Scopus)

Effectiveness of Exercise, Cognitive Behavioral Therapy, and Pharmacotherapy on Improving Sleep in Adults with Chronic Insomnia: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials

Yu, D. J., Recchia, F., Bernal, J. D. K., Yu, A. P., Fong, D. Y., Li, S. X., Chan, R. N. Y., Hu, X. & Siu, P. M., 1 Aug 2023, In: Healthcare. 11, 15, 12 p., 2207.

Research output: Contribution to journal › Journal article › peer-review

Open Access

5 Citations (Scopus)

Effects of Tai Chi and cognitive behavioral therapy for insomnia on improving sleep in older adults: Study protocol for a non-inferiority trial

Yu, D. J., Yu, A. P., Li, S. X., Chan, R. N. Y., Fong, D. Y., Chan, D. K. C., Hui, S. S., Chung, K. F., Woo, J., Wang, C., Irwin, M. R. & Siu, P. M., Jan 2023, In: Journal of Exercise Science and Fitness. 21, 1, p. 67-73 7 p.

Research output: Contribution to journal › Journal article › peer-review

Open Access

2 Citations (Scopus)

Evidence-based Chinese medicine clinical practice guideline on menopausal syndrome in Hong Kong

Li, H., Yeung, T. C., Zhang, C., Meng, W., Miao, J. X. & Zhong, L. L., Jan 2023, In: European Journal of Integrative Medicine. 57, 9 p., 102213.

Research output: Contribution to journal › Journal article › peer-review

Open Access

2 Citations (Scopus)

Gut microbiota-derived tryptamine and phenethylamine impair insulin sensitivity in metabolic syndrome and irritable bowel syndrome

Zhai, L., Xiao, H., Lin, C., Wong, H. L. X., Lam, Y. Y., Gong, M., Wu, G., Ning, Z., Huang, C., Zhang, Y., Yang, C., Luo, J., Zhang, L., Zhao, L., Zhang, C., Lau, J.Y.-N., Lu, A., Lau, L.-T., Jia, W. & Zhao, L. & 1 others, Bian, Z.-X., 17 Aug 2023, In: Nature Communications. 14, 1, 14 p., 4986.

Research output: Contribution to journal › Journal article › peer-review

Open Access

34 Citations (Scopus)

Minocycline, a classic antibiotic, exerts psychotropic effects by normalizing microglial neuroinflammation-evoked tryptophan-kynurenine pathway dysregulation in chronically stressed male mice

Cheng, D., Qin, Z.-S., Zheng, Y., Xie, J.-Y., Liang, S.-S., Zhang, J.-L., Feng, Y.-B. & Zhang, Z.-J., Jan 2023, In: Brain, Behavior, and Immunity. 107, p. 305-318 14 p.

Research output: Contribution to journal › Journal article › peer-review

24 Citations (Scopus)

Network Pharmacology Study of Bioactive Components and Molecular Mechanisms of the Glycoside Fraction from Picrorhiza scrophulariiflora Against Experimental Colitis

Wu, P., Chang, C., Zhu, G., Zhai, L., Zhang, X., Huan, Q., Gao, Z., Deng, H., Liang, Y. & Xiao, H., 23 May 2023, In: Drug Design, Development and Therapy. 17, p. 1531-1546 16 p.

Research output: Contribution to journal › Journal article › peer-review

Open Access

3 Citations (Scopus)

Physical activity and exercise for cancer-related cognitive impairment among individuals affected by childhood cancer: a systematic review and meta-analysis

Bernal, J. D. K., Recchia, F., Yu, D. J., Fong, D. Y., Wong, S. H. S., Chung, P. K., Chan, D. K. C., Capio, C. M., Yu, C. C. W., Wong, S. W. S., Sit, C. H. P., Chen, Y. J., Thompson, W. R. & Siu, P. M., Jan 2023, In: The Lancet Child and Adolescent Health. 7, 1, p. 47-58 12 p.

Research output: Contribution to journal › Journal article › peer-review

15 Citations (Scopus)

Prevalence and risk factors of long COVID 6–12 months after infection with the Omicron variant among nonhospitalized patients in Hong Kong

Luo, J., Zhang, J., Tang, H. T., Wong, H. K., Lyu, A., Cheung, C. H. & Bian, Z., Jun 2023, In: Journal of Medical Virology. 95, 6, 12 p., e28862.

Research output: Contribution to journal › Journal article › peer-review

Open Access

15 Citations (Scopus)

Protocol for the development of a reporting guideline for clinical trials with integrated Chinese and western medicine interventions: the CONSORT extension for ICWM

Wang, J., Zhang, X., Wang, P., Han, F., Li, J., Lu, A. & Bian, Z., 29 Jun 2023, In: Frontiers in Medicine. 10, 8 p., 1190560.

Research output: Contribution to journal › Journal article › peer-review

Open Access

Protocol of the CONSORT and SPIRIT Extension for multicenter clinical trials

Zhang, X., Dong, C., Wang, N., Chan, C. P., Lau, C. T., Wang, J., Miao, J., Yao, C., Li, Y., Lu, A., Moher, D. & Bian, Z., 15 Sept 2023, In: Frontiers in Public Health. 11, 6 p., 1241152.

Research output: Contribution to journal › Journal article › peer-review

Open Access

1 Citation (Scopus)

Quality of reporting of integrative Chinese and Western medicine intervention in randomized controlled trials of ulcerative colitis: a review

Zhang, J., Deng, J., Wang, N., Wang, P., Li, J., Wang, Y., Cui, W., Liang, F., Chen, P., Wang, J., Han, F., Chan, C. P., Lyu, A., Bian, Z. & Zhang, X., 8 Dec 2023, In: Systematic Reviews. 12, 13 p., 228.

Research output: Contribution to journal › Journal article › peer-review

Open Access

1 Citation (Scopus)

Reporting quality of randomized controlled trials of angina pectoris with integrated traditional Chinese and western medicine interventions: a cross-sectional study

Deng, J., He, J., Wang, J., Cheng, C. W., Jiao, Y., Wang, N., Li, J., Wang, P., Han, F., Lyu, A., Bian, Z. & Zhang, X., 23 May 2023, In: BMC Medical Research Methodology. 23, 1, 12 p., 124.

Research output: Contribution to journal › Journal article › peer-review

Open Access

1 Citation (Scopus)

Ruminococcus gnavus plays a pathogenic role in diarrhea-predominant irritable bowel syndrome by increasing serotonin biosynthesis

Zhai, L., Huang, C., Ning, Z., Zhang, Y., Zhuang, M., Yang, W., Wang, X., Wang, J., Zhang, L., Xiao, H., Zhao, L., Asthana, P., Lam, Y. Y., Chow, C. F. W., Huang, J. D., Yuan, S., Chan, K. M., Yuan, C. S., Lau, J. Y. N. & Wong, H. L. X. & 1 others, Bian, Z. X., 11 Jan 2023, In: Cell Host and Microbe. 31, 1, p. 33-44.e5 12 p.

Research output: Contribution to journal › Journal article › peer-review

55 Citations (Scopus)

STandards for Reporting Interventions in Clinical Trials Of Tuina/Massage (STRICTOTM): Extending the CONSORT statement

Zhang, X., Liang, F., Lau, C. T., Chan, J. C., Wang, N., Deng, J., Wang, J., Ma, Y., Zhong, L. L. D., Zhao, C., Yao, L., Wu, T., Lyu, A., Tian, G., Shang, H., Miao, J., Bian, Z. & STRICTOTM Working Group, 14 Mar 2023, In: Journal of Evidence-Based Medicine. 16, 1, p. 68-81 14 p.

Research output: Contribution to journal › Journal article › peer-review

Open Access

9 Citations (Scopus)

Validation of evidence-based questionnaire for TCM syndrome differentiation of heart failure and evaluation of expert consensus

Leung, A. Y. L., Zhang, J., Chan, C. Y., Chen, X., Mao, J., Jia, Z., Li, X. & Shen, J., 9 Jun 2023, In: Chinese Medicine. 18, 20 p., 70.

Research output: Contribution to journal › Journal article › peer-review

Open Access

4 Citations (Scopus)

Validation of the Cantonese Version of the Traditional Chinese Medicine (TCM) Body Constitution Questionnaire in Elderly People

Wong, Y. L., Zhang, J., Wu, X., Wong, S. Y., Wang, Z., Zhong, L. & Bian, Z., 11 Oct 2023, In: Chinese Medicine. 18, 1, 19 p., 129.

Research output: Contribution to journal › Journal article › peer-review

Open Access

2 Citations (Scopus)

Weekly symptom profiles of nonhospitalized individuals infected with SARS-CoV-2 during the Omicron outbreak in Hong Kong: A retrospective observational study from a telemedicine center

Luo, J., Zhang, J., Tang, H. T., Wong, H. K., Ma, Y., Xie, D., Peng, B., Lyu, A., Cheung, C. H. & Bian, Z., Feb 2023, In: Journal of Medical Virology. 95, 2, 10 p., e28447.

Research output: Contribution to journal › Journal article › peer-review

Open Access

7 Citations (Scopus)

Chinese Medicine - Clinical Division

Research Output

Search results