The HKBU’s “Outstanding Research Output Award 2024” honours two researchers in the School of Chinese Medicine (SCM).
The researchers’ award-winning papers in the Health and Drug Discovery cluster focus on potential therapeutic interventions for Alzheimer’s Disease and obesity.
Dr. Iyaswamy’s study, “Fe65-engineered neuronal exosomes encapsulating corynoxineB ameliorate cognition and pathology of Alzheimer’s disease,” focuses on the interaction between two proteins – APP and Fe65 – in an AD brain and a novel approach to deliver Corynoxine-B to the brain using engineered exosomes. This leads to the amelioration of cognitive functions such as learning and memory and reducing Aβ pathogenesis in AD preclinical models, demonstrating the potential of Fe65-EXO-Cory-B as an e ective therapeutic intervention for AD.